The stress sigma factor σS/RpoS counteracts Fur repression of genes involved in iron and manganese metabolism and modulates the ionome of Salmonella enterica serovar Typhimurium.

Autor: Selma Metaane, Véronique Monteil, Sophie Ayrault, Louise Bordier, Corinne Levi-Meyreuis, Françoise Norel

Publikováno v: PLoS ONE, Vol 17, Iss 3, p e0265511 (2022)

In many Gram-negative bacteria, the stress sigma factor of RNA polymerase, σS/RpoS, remodels global gene expression to reshape the physiology of quiescent cells and ensure their survival under non-optimal growth conditions. In the foodborne pathogen

Externí odkaz: https://doaj.org/article/9008862b773541a1a85c88578281934b

Proteome remodelling by the stress sigma factor RpoS/σS in Salmonella: identification of small proteins and evidence for post-transcriptional regulation

Autor: Magali Lago, Véronique Monteil, Thibaut Douche, Julien Guglielmini, Alexis Criscuolo, Corinne Maufrais, Mariette Matondo, Françoise Norel

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)

Abstract The RpoS/σS sigma subunit of RNA polymerase is the master regulator of the general stress response in many Gram-negative bacteria. Extensive studies have been conducted on σS-regulated gene expression at the transcriptional level. In contr

Externí odkaz: https://doaj.org/article/269a55cf5d5b4048bfff1bf7dea0c7b7

Escherichia coli Genomic Diversity within Extraintestinal Acute Infections Argues for Adaptive Evolution at Play

Autor: Véronique Robbe-Saule, Antoine Bridier-Nahmias, Sara Dion, Alexandre Bleibtreu, Françoise Norel, Olivier Clermont, Adrien Launay, Violaine Walewski, Erick Denamur, Mélanie Magnan, Olivier Tenaillon, Jérémie Chatel

Publikováno v: mSphere
mSphere, Vol 6, Iss 1 (2021)
MSphere
MSphere, 2021, 6 (1), pp.e01176-20. ⟨10.1128/mSphere.01176-20⟩
MSphere, American Society for Microbiology., 2021, 6 (1), pp.e01176-20. ⟨10.1128/mSphere.01176-20⟩

Little is known about the dynamics of adaptation in acute bacterial infections. By sequencing multiple isolates from monoclonal extraintestinal Escherichia coli infections in several patients, we were able to uncover traces of selection taking place

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d588c6646abbbfa644b3d1d8ed515e28
http://europepmc.org/articles/PMC7845604

Molecular and evolutionary bases of within-patient genotypic and phenotypic diversity in Escherichia coli extraintestinal infections.

Autor: Maxime Levert, Oana Zamfir, Olivier Clermont, Odile Bouvet, Sylvain Lespinats, Marie Claire Hipeaux, Catherine Branger, Bertrand Picard, Claude Saint-Ruf, Françoise Norel, Thierry Balliau, Michel Zivy, Hervé Le Nagard, Stéphane Cruveiller, Béatrice Chane-Woon-Ming, Susanna Nilsson, Ivana Gudelj, Katherine Phan, Thomas Ferenci, Olivier Tenaillon, Erick Denamur

Publikováno v: PLoS Pathogens, Vol 6, Iss 9, p e1001125 (2010)

Although polymicrobial infections, caused by combinations of viruses, bacteria, fungi and parasites, are being recognised with increasing frequency, little is known about the occurrence of within-species diversity in bacterial infections and the mole

Externí odkaz: https://doaj.org/article/e7451ec319ce496eb724fc67d8419d94

The stress sigma factor of RNA polymerase RpoS/σ S is a solvent-exposed open molecule in solution

Autor: Christina Sizun, Julia Chamot-Rooke, Françoise Bonneté, Sébastien Brier, Claudine Mayer, Bertrand Raynal, Françoise Norel, Patrick England, Paola Cavaliere, Fabienne Levi-Acobas, Petr Filipenko, Jacques Bellalou

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2018, 475 (1), pp.341-354. ⟨10.1042/BCJ20170768⟩
Biochemical Journal, Portland Press, 2018, 475 (1), pp.341-354. 〈10.1042/BCJ20170768〉
Biochemical Journal, 2018, 475 (1), pp.341-354. ⟨10.1042/BCJ20170768⟩

International audience; In bacteria, one primary and multiple alternative sigma (σ) factors associate with the RNA polymerase core enzyme (E) to form holoenzymes (Eσ) with different promoter recognition specificities. The alternative σ factor RpoS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af9a5bed177c502c9d4e170be5e4403
https://hal-pasteur.archives-ouvertes.fr/pasteur-01685123/document