Zobrazeno 1 - 10
of 51
pro vyhledávání: '"François Villinger"'
Autor:
Siqi Gong, Samir K. Lakhashe, Dinesh Hariraju, Hanna Scinto, Antonio Lanzavecchia, Elisabetta Cameroni, Davide Corti, Sarah J. Ratcliffe, Kenneth A. Rogers, Peng Xiao, Jane Fontenot, François Villinger, Ruth M. Ruprecht
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Understanding the interplay between systemic and mucosal anti-HIV antibodies can provide important insights to develop new prevention strategies. We used passive immunization via systemic and/or mucosal routes to establish cause-and-effect between we
Externí odkaz:
https://doaj.org/article/46765fdad160479eb7819948e8f76c25
Autor:
Laury-Anne Leroy, Alice Mac Donald, Aditi Kandlur, Deepanwita Bose, Peng Xiao, Jean Gagnon, François Villinger, Yahia Chebloune
Publikováno v:
Vaccines, Vol 10, Iss 3, p 461 (2022)
HIV-1 remains a major public health issue worldwide in spite of efficacious antiviral therapies, but with no cure or preventive vaccine. The latter has been very challenging, as virus infection is associated with numerous escape mechanisms from host
Externí odkaz:
https://doaj.org/article/777b00cd7c5e4b79a9e31658feafa67e
Autor:
Viswanathan Ramasamy, Upasana Arora, Rahul Shukla, Ankur Poddar, Rajgokul K Shanmugam, Laura J White, Melissa M Mattocks, Rajendra Raut, Ashiya Perween, Poornima Tyagi, Aravinda M de Silva, Siddhartha K Bhaumik, Murali Krishna Kaja, François Villinger, Rafi Ahmed, Robert E Johnston, Sathyamangalam Swaminathan, Navin Khanna
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 1, p e0006191 (2018)
Dengue is one of the fastest spreading vector-borne diseases, caused by four antigenically distinct dengue viruses (DENVs). Antibodies against DENVs are responsible for both protection as well as pathogenesis. A vaccine that is safe for and efficacio
Externí odkaz:
https://doaj.org/article/1493e4510e824e5a9dcf9fc2b8abf687
Autor:
Béatrice Jacquelin, Gaël Petitjean, Désirée Kunkel, Anne-Sophie Liovat, Simon P Jochems, Kenneth A Rogers, Mickaël J Ploquin, Yoann Madec, Françoise Barré-Sinoussi, Nathalie Dereuddre-Bosquet, Pierre Lebon, Roger Le Grand, François Villinger, Michaela Müller-Trutwin
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004241 (2014)
Chronic immune activation (IA) is considered as the driving force of CD4(+) T cell depletion and AIDS. Fundamental clues in the mechanisms that regulate IA could lie in natural hosts of SIV, such as African green monkeys (AGMs). Here we investigated
Externí odkaz:
https://doaj.org/article/fa8de60be3134b30aff1786ab24f2a00
Autor:
Géraldine Arrode-Brusés, Maha Moussa, Monique Baccard-Longere, François Villinger, Yahia Chebloune
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110883 (2014)
Prevention of HIV acquisition and replication requires long lasting and effective immunity. Given the state of HIV vaccine development, innovative vectors and immunization strategies are urgently needed to generate safe and efficacious HIV vaccines.
Externí odkaz:
https://doaj.org/article/71c69a9cfcf2439693c78928b36d4f96
Publikováno v:
PLoS Pathogens, Vol 7, Iss 8, p e1002055 (2011)
Cytokines play a central role in the pathogenesis of many diseases, including HIV infection. However, the role of the cytokine network in early HIV infection is only now starting to be elucidated. A number of studies conducted in recent years have in
Externí odkaz:
https://doaj.org/article/5befb8172cdd415c85b43d7c5183e8b9
Autor:
Prachi Sharma, Kenneth A. Rogers, Suganthi Suppiah, Ross J. Molinaro, Nattawat Onlamoon, John Hackett, Gerald Schochetman, Eric A. Klein, Robert H. Silverman, François Villinger
Publikováno v:
Advances in Virology, Vol 2011 (2011)
Although XMRV dissemination in humans is a matter of debate, the prostate of select patients seem to harbor XMRV, which raises questions about its potential route of transmission. We established a model of infection in rhesus macaques inoculated with
Externí odkaz:
https://doaj.org/article/53adc33165dd47b0a5e93a5a049007d6
Autor:
Samir K Lakhashe, Wendy Wang, Nagadenahalli B Siddappa, Girish Hemashettar, Patricia Polacino, Shiu-Lok Hu, François Villinger, James G Else, Francis J Novembre, John K Yoon, Sandra J Lee, David C Montefiori, Ruth M Ruprecht, Robert A Rasmussen
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22010 (2011)
A safe, efficacious vaccine is required to stop the AIDS pandemic. Disappointing results from the STEP trial implied a need to include humoral anti-HIV-1 responses, a notion supported by RV144 trial data even though correlates of protection are unkno
Externí odkaz:
https://doaj.org/article/8751dd96775544e8b63d061f3c9c7bda
Autor:
Nagadenahalli B Siddappa, Jennifer D Watkins, Klemens J Wassermann, Ruijiang Song, Wendy Wang, Victor G Kramer, Samir Lakhashe, Michael Santosuosso, Mark C Poznansky, Francis J Novembre, François Villinger, James G Else, David C Montefiori, Robert A Rasmussen, Ruth M Ruprecht
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11689 (2010)
HIV-1 clade C (HIV-C) predominates worldwide, and anti-HIV-C vaccines are urgently needed. Neutralizing antibody (nAb) responses are considered important but have proved difficult to elicit. Although some current immunogens elicit antibodies that neu
Externí odkaz:
https://doaj.org/article/2b65cdf4efde4596bb2e19d63df55805
Autor:
Stéphane Pillet, Prabhu S. Arunachalam, Guadalupe Andreani, Nadia Golden, Jane Fontenot, Pyone Pyone Aye, Katharina Röltgen, Gabrielle Lehmicke, Philipe Gobeil, Charlotte Dubé, Sonia Trépanier, Nathalie Charland, Marc-André D’Aoust, Kasi Russell-Lodrigue, Christopher Monjure, Robert V. Blair, Scott D. Boyd, Rudolf P. Bohm, Jay Rappaport, François Villinger, Nathalie Landry, Bali Pulendran, Brian J. Ward
Publikováno v:
Cellular and Molecular Immunology
Although antivirals are important tools to control severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, effective vaccines are essential to control the current coronavirus disease 2019 (COVID-19) pandemic. Plant-derived virus-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196ab61cd1a7251d30167a864e952c12
https://doi.org/10.1038/s41423-021-00809-2
https://doi.org/10.1038/s41423-021-00809-2