Zobrazeno 1 - 6
of 6
pro vyhledávání: '"François Turtaut"'
Autor:
Jean-Yves Winum, Jérémie Mortier, Pascale Joseph, Marie-Rose Abdo, Stephan Köhler, François Turtaut, Bernard Masereel, Jean-Louis Montero
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2011, 9 (10), pp.3681. ⟨10.1039/c1ob05149k⟩
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2011, 9 (10), pp.3681. ⟨10.1039/c1ob05149k⟩
International audience; In the facultative intracellular pathogen Brucella suis, histidinol dehydrogenase (HDH) activity, catalyzing the last step in histidine biosynthesis, is essential for intramacrophagic replication. The inhibition of this virule
Publikováno v:
Organic Letters
Organic Letters, American Chemical Society, 2008, 10 (15), pp.3203-3206. ⟨10.1021/ol801025u⟩
Organic Letters, American Chemical Society, 2008, 10 (15), pp.3203-3206. ⟨10.1021/ol801025u⟩
International audience; We have developed an inexpensive catalytic system using a readily available copper/ligand combination for the Sonogashira-type cross-coupling of aryl iodides and phenyl- and hexyl-acetylene which affords disubstituted alkynes
Publikováno v:
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, 2014, 24 (21), pp.5008-5010. ⟨10.1016/j.bmcl.2014.09.020⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2014, 24 (21), pp.5008-5010. ⟨10.1016/j.bmcl.2014.09.020⟩
Bioorganic and Medicinal Chemistry Letters, 2014, 24 (21), pp.5008-5010. ⟨10.1016/j.bmcl.2014.09.020⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2014, 24 (21), pp.5008-5010. ⟨10.1016/j.bmcl.2014.09.020⟩
International audience; Histidinol dehydrogenase (HDH) has been established as a virulence factor for the human pathogen bacterium Brucella suis. Targeting such a virulence factor is a relevant anti-infectious approach as it could decrease the freque
Autor:
Pascale Joseph, Isao Nishimori, Claudiu T. Supuran, Andrea Scozzafava, Jean-Louis Montero, François Turtaut, Tomoko Minakuchi, Safia Ouahrani-Bettache, Jean-Yves Winum, Stephan Köhler, Daniela Vullo
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2010, 53 (5), pp.2277-85. ⟨10.1021/jm901855h⟩
Journal of Medicinal Chemistry, American Chemical Society, 2010, 53 (5), pp.2277-85. ⟨10.1021/jm901855h⟩
International audience; A beta-carbonic anhydrase (CA, EC 4.2.1.1) from the bacterial pathogen Brucella suis, bsCA 1, has been cloned, purified, and characterized kinetically. bsCA 1 has appreciable activity as catalyst for the hydration of CO(2) to
Publikováno v:
Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ebb1ee188628d99593f5c787942c2eb
https://doi.org/10.1002/9780470508169.ch38
https://doi.org/10.1002/9780470508169.ch38
Publikováno v:
ChemInform. 39