Zobrazeno 1 - 10
of 58
pro vyhledávání: '"François St-Pierre"'
Autor:
Ruth R. Sims, Imane Bendifallah, Christiane Grimm, Aysha S. Mohamed Lafirdeen, Soledad Domínguez, Chung Yuen Chan, Xiaoyu Lu, Benoît C. Forget, François St-Pierre, Eirini Papagiakoumou, Valentina Emiliani
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Two-photon voltage imaging has long been heralded as a transformative approach capable of answering many long-standing questions in modern neuroscience. However, exploiting its full potential requires the development of novel imaging approac
Externí odkaz:
https://doaj.org/article/80d79b45194c4cc0934fc6000f7a388a
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Widefield imaging with genetically encoded voltage indicators (GEVIs) is a promising approach for understanding the role of large cortical networks in the neural coding of behavior. However, the limited performance of current GEVIs restricts
Externí odkaz:
https://doaj.org/article/c1aeaafd7f194a15b4104d77223a88d9
Autor:
Shuyuan Yang, Xiaoyu Lu, Michelle Land, Zhuohe Liu, Alex Mcdonald, Yueyang Gou, Yunmiao Wang, Elsayed Zaabout, Xiaoyu Dong, Shujuan Lai, Dieter Jaeger, Jacob Reimer, François St-Pierre
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S264-S265 (2023)
Externí odkaz:
https://doaj.org/article/11e80b2fc5074767a58be6b5de10ce94
Autor:
Benjamin B. Kim, Haodi Wu, Yukun A. Hao, Michael Pan, Mariya Chavarha, Yufeng Zhao, Michael Westberg, François St-Pierre, Joseph C. Wu, Michael Z. Lin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract A ratiometric genetically encoded voltage indicator (GEVI) would be desirable for tracking transmembrane voltage changes in the presence of sample motion. We performed combinatorial multi-site mutagenesis on a cyan-excitable red fluorescent
Externí odkaz:
https://doaj.org/article/1abe5a648e004c5c9e32c66a22320ec1
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Transient plasmid transfection produces a wide distribution of copy numbers and expression heterogeneity. Here the authors present synthetic circuits called Equalizers that buffer copy number variation at the single-cell level and minimize cell-to-ce
Externí odkaz:
https://doaj.org/article/3624485f7c5c49edb625fe43b2b5f8d9
Autor:
Simon Chamberland, Helen H Yang, Michael M Pan, Stephen W Evans, Sihui Guan, Mariya Chavarha, Ying Yang, Charleen Salesse, Haodi Wu, Joseph C Wu, Thomas R Clandinin, Katalin Toth, Michael Z Lin, François St-Pierre
Publikováno v:
eLife, Vol 6 (2017)
Monitoring voltage dynamics in defined neurons deep in the brain is critical for unraveling the function of neuronal circuits but is challenging due to the limited performance of existing tools. In particular, while genetically encoded voltage indica
Externí odkaz:
https://doaj.org/article/50069514a87340df8d7fa70279b37ba0
Autor:
Ruth Sims, Imane Bendifallah, Christiane Grimm, Aysha Lafirdeen, Xiaoyu Lu, François St-Pierre, Eirini Papagiakoumou, Valentina Emiliani
Parallel light-sculpting methods have been used to perform scanless two-photon photostimulation of multiple neurons simultaneously during all-optical neurophysiology experiments. We demonstrate that scanless two-photon excitation also enables high-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72b96e03add1f9f70d17b933c4ec2f17
https://doi.org/10.21203/rs.3.rs-2412371/v1
https://doi.org/10.21203/rs.3.rs-2412371/v1
Autor:
Jihwan Lee, Beatriz Campillo, Shaminta Hamidian, Zhuohe Liu, Matthew Shorey, François St-Pierre
Publikováno v:
Biochemistry.
Over the last 25 years, protein engineers have developed an impressive collection of optical tools to interface with biological systems: indicators to eavesdrop on cellular activity and actuators to poke and prod native processes. To reach the perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff0cf9ed68e7b0b734b05513e818732
https://pubmed.ncbi.nlm.nih.gov/36315460
https://pubmed.ncbi.nlm.nih.gov/36315460
Autor:
Zhuohe Liu, Xiaoyu Lu, Vincent Villette, Yueyang Gou, Kevin L. Colbert, Shujuan Lai, Sihui Guan, Michelle A. Land, Jihwan Lee, Tensae Assefa, Daniel R. Zollinger, Maria M. Korympidou, Anna L. Vlasits, Michelle M. Pang, Sharon Su, Changjia Cai, Emmanouil Froudarakis, Na Zhou, Saumil S. Patel, Cameron L. Smith, Annick Ayon, Pierre Bizouard, Jonathan Bradley, Katrin Franke, Thomas R. Clandinin, Andrea Giovannucci, Andreas S. Tolias, Jacob Reimer, Stéphane Dieudonné, François St-Pierre
Publikováno v:
Cell
Cell, 2022, 185 (18), pp.3408-3425.e29. ⟨10.1016/j.cell.2022.07.013⟩
Cell, 2022, 185 (18), pp.3408-3425.e29. ⟨10.1016/j.cell.2022.07.013⟩
International audience; Genetically encoded voltage indicators are emerging tools for monitoring voltage dynamics with cell-type specificity. However, current indicators enable a narrow range of applications due to poor performance under two-photon m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628e7939a22097f1a78b007bb0e76580
https://hal.science/hal-03795400/document
https://hal.science/hal-03795400/document
Autor:
Christian Behrens, Shubhash Chandra Yadav, Maria M. Korympidou, Yue Zhang, Silke Haverkamp, Stephan Irsen, Anna Schaedler, Xiaoyu Lu, Zhuohe Liu, Jan Lause, François St-Pierre, Katrin Franke, Anna Vlasits, Karin Dedek, Robert G. Smith, Thomas Euler, Philipp Berens, Timm Schubert
Publikováno v:
Curr Biol
Current Biology
Current Biology
In the outer plexiform layer (OPL) of the mammalian retina, cone photoreceptors (cones) provide input to more than a dozen types of cone bipolar cells (CBCs). In the mouse, this transmission is modulated by a single horizontal cell (HC) type. HCs per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a4741933e96e351851d656242b1224
https://europepmc.org/articles/PMC8886496/
https://europepmc.org/articles/PMC8886496/