Zobrazeno 1 - 10
of 10
pro vyhledávání: '"François Romagne"'
Publikováno v:
Journal of Immunotherapy. 31:313-323
We previously showed that Vdelta2 T cells infiltrate renal tumors and can be expanded as potent cytotoxic effectors from peripheral blood mononuclear cells of most renal cell carcinoma (RCC) patients, using a structural analog of nonconventional T-ce
Autor:
Thierry Rème, François Romagne, Maud Condomines, Bernard Klein, Philippe Quittet, Jean François Rossi, Cécile Lugagne, Z. Y. Lu, Maka Burjanadzé, Pascal Latry, Yanis Morel
Publikováno v:
British Journal of Haematology. 139:206-216
T-cell-mediated immunotherapy is a promising therapeutic option for multiple myeloma (MM). Gamma-delta T cells (gammadelta T cells) recognize phosphoantigens and display strong anti-tumour cytotoxicity. The synthetic agonist Phosphostim (bromohydrin
Autor:
François Dabis, Jean-Luc Taupin, Fabrice Bonnet, Jean-François Moreau, Jean-Luc Pellegrin, Jeannette Texier-Maugein, Stéphane Sire, François Romagne, Denis Lacoste, Jean-Marie Ragnaud, Michel Dupon, Laurence Dequae-Merchadou
Publikováno v:
Microbes and Infection. 1:771-776
In a retrospective study, an increase in double-negative (CD3+ CD4- CD8-) (DN) T lymphocytes has been shown to be an independent predictor of disseminated Mycobacterium avium complex (D.MAC) infection in patients with less than 100 CD4+ T cells per m
Autor:
Samuel, Salot, Catherine, Laplace, Soraya, Saïagh, Sylvain, Bercegeay, Isabelle, Tenaud, Alain, Cassidanius, François, Romagne, Brigitte, Dreno, Jérôme, Tiollier
Publikováno v:
Journal of immunological methods. 326(1-2)
gamma9delta2 T lymphocytes are non-conventional lymphocytes presenting a direct cytotoxic effect against a broad range of tumour targets. These cells also secrete inflammatory cytokines that can boost the other components of the immune system. In con
Autor:
Harout Dersimonian, Michael B. Brenner, Arnaud Dupuy D'Angeac, Thierry Rème, Adolfo Travaglio-Encinozal, Jacques Sany, Christian Jorgensen, François Romagne
Publikováno v:
Annals of the New York Academy of Sciences. 756:201-203
Autor:
Corinne Rocher, Thierry Hercend, François Romagne, Anita Diu, Alain David, Jean-Michel Bruneau, Catherine Genevée, Françchise Praz
Publikováno v:
European journal of immunology. 23(7)
Seven distinct anti-human T cell receptor (TcR) V region monoclonal antibodies (mAb) were generated by immunizing mice with either human T cell lines or transfected murine cells expressing human TcR V beta genes. The specificity of these reagents was
Autor:
Agnès Represa, Patrick Dennler, Yannis Morel, François Romagné, Delphine Bregeon, Angelique Boedec, Florence Lhospice, Roger Schibli, Christian Belmant
Publikováno v:
Cancer Research. 74:2514-2514
Purpose : Bacterial Transglutaminase (BTG) allows coupling on endogenous Q295 from an aglycosylated antibody. Here, the work relates to ADCs synthesis through BTG approach on mAbs with single point mutations and the study of stability, pharmacokineti
Autor:
Ariane Thielens, Stéphanie Cornen, Valentine Peri, Laurent Gauthier, Mathieu Blery, Ivan Perrot, Cécile Bonnafous, Sylvia Trichard, Yannis Morel, François Romagné, Benjamin Rossi, Carine Paturel, Violette Breso
Publikováno v:
Cancer Research. 74:5037-5037
MICA and MICB, along with ULPBs, are ligands for the activating receptor NKG2D expressed on NK cells and subsets of T cells in Human. NKG2D ligands are induced by cellular stress and pathogen infections. Their expression is tightly regulated by compl
Autor:
Mathieu Blery, Isabelle Palacios, Sophie Ugolini, Cécile Bonnafous, Pascale Andre, Ariane Thielens, Nicolas Fuseri, Eric Vivier, Fabien Chanuc, Caroline Sola, François Romagné, Robert F. Graziano
Publikováno v:
Cancer Research. 73:493-493
Natural Killer cells (NK cells) are lymphocytes able to recognize and kill tumors for which the expression of Major Histocompatibility Complex (MHC) class I molecules is altered. This “missing self” recognition is mediated in humans by the lack o
Autor:
Lorenzo Galluzzi, Nils-Petter Rudqvist
Tumor Immunology and Immunotherapy - Integrated Methods Part B, Volume 636 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this update include Quanti