Zobrazeno 1 - 10
of 24
pro vyhledávání: '"François Nantel"'
Autor:
Emmanouil Rampakakis, Majed Khraishi, Maqbool Sheriff, Dalton Sholter, Allen J Lehman, François Nantel, Regan Arendse
Publikováno v:
BMJ Open, Vol 10, Iss 8 (2020)
Externí odkaz:
https://doaj.org/article/c18b6b42580446cb9bf3656de87a2220
Autor:
Emmanouil Rampakakis, John S Sampalis, Susan Otawa, Proton Rahman, Michel Zummer, Andrew Chow, May Shawi, Majed Khraishi, Denis Choquette, William G Bensen, Saeed Shaikh, Maqbool Sheriff, Sanjay Dixit, Dalton Sholter, Eliofotisti Psaradellis, Vincent Letourneau, Allen J Lehman, François Nantel
Publikováno v:
BMJ Open, Vol 6, Iss 4 (2016)
Objectives To describe the profile of patients with ankylosing spondylitis (AS) treated with infliximab in Canadian routine care and to assess the effectiveness and safety of infliximab in real world.Setting 46 primary care rheumatology practices acr
Externí odkaz:
https://doaj.org/article/d179726233ae4da69c959a990fa648ba
Publikováno v:
Clinical and Experimental Rheumatology. 38:371-371
Publikováno v:
European Journal of Pharmacology. 514:69-78
Diffuse vasculopathy is a common feature of the morbidity and increased mortality associated with insulino-dependent type 1 diabetes. Increased vascular permeability leading to plasma extravasation occurs in surrounding tissues following endothelial
Autor:
Richard Friesen, Gillian Greig, Nicole Sawyer, Bernard Cote, Stacia Kargman, Sonia Lamontagne, Kathleen M. Metters, Richard Frenette, Yves Ducharme, Gary P. O'Neill, François Nantel, Marie-Claude Carrière, Evelyn Martins, Anne Chateauneuf, Danielle Denis, Marc Blouin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1155-1160
The synthesis and the EP(1) receptor binding affinity of 2,3-diarylthiophene derivatives are described. The evaluation of the structure-activity relationship (SAR) in this series led to the identification of compounds 4, 7, and 12a, which exhibit hig
Autor:
Kathleen M. Metters, Martin Desrosiers, Gary P. O'Neill, François G. Gervais, Carolyn Fong, Sonia Lamontagne, François Nantel, D. Hamish Wright, Adel Giaid
Publikováno v:
Prostaglandins & Other Lipid Mediators. 73:87-101
Rationale Prostaglandin D 2 (PGD 2 ) is released from mast cells during the allergic response. Since PGD 2 has been shown to induce nasal congestion in humans, we investigated the distribution of hematopoietic Prostaglandin D synthase (PGDS) and the
Autor:
Anne Chateauneuf, Gary P. O'Neill, Rani P.G. Cruz, Stephen Gale, François G. Gervais, François Nantel, Kathleen M. Metters, Nicole Sawyer
Publikováno v:
Journal of Allergy and Clinical Immunology. 108:982-988
Background: PGD 2 is the major prostanoid released by mast cells during an allergic response. Its role in the allergic response, however, remains unclear. Objective: Because the accumulation of eosinophils is a feature of allergic reactions, we inves
Autor:
François Nantel, Thomas E. Scammell, Takakazu Oka, Kae Oka, Charlotte E. Lee, Joel K. Elmquist, Clifford B. Saper, Joseph Kelly
Publikováno v:
The Journal of Comparative Neurology. 428:20-32
The action of prostaglandin E(2) (PGE(2)) in the preoptic area is thought to play an important role in producing fever. Pharmacologic evidence suggests that, among the four subtypes of E-series prostaglandin (EP) receptors, i.e., EP(1), EP(2), EP(3),
Autor:
Kathleen M. Metters, Maria Cirino, Chi-Chung Chan, François Nantel, Robert Gordon, Angela Northey, Danielle Denis
Publikováno v:
British Journal of Pharmacology. 128:853-859
1 We characterized the regulation of cyclooxygenase-2 (COX-2) at the mRNA, protein and mediator level in two rat models of acute inflammation, carrageenan-induced paw oedema and mechanical hyperalgesia. 2 Carrageenan was injected in the hind paw of r
Autor:
Kathleen M. Metters, Emily Meadows, Brett Connolly, Adel Giaid, Danielle Denis, François Nantel
Publikováno v:
FEBS Letters. 457:475-477
To gain insight into the role of prostanoids in human kidney function, we examined the distribution of cyclooxygenase (COX) 1 and COX-2 by immunofluorescence and immunohistochemistry in human kidneys from adults of various age groups. COX-1 was detec