Zobrazeno 1 - 10
of 98
pro vyhledávání: '"François Mouton‐Liger"'
Autor:
Louise Sindzingre, Elodie Bouaziz-Amar, François Mouton-Liger, Emmanuel Cognat, Julien Dumurgier, Agathe Vrillon, Claire Paquet, Matthieu Lilamand
Publikováno v:
The Journal of Nutrition, Health and Aging, Vol 28, Iss 3, Pp 100166- (2024)
Adiponectin is an adipokine playing a central role in the regulation of energy homeostasis, carbohydrate and lipid metabolism, as well as immunomodulation. The relationship between Alzheimer’s disease (AD) and body composition has highlighted the b
Externí odkaz:
https://doaj.org/article/283fc908e50745bc80613a95ba9c8b60
Autor:
Dominique Gouilly, Agathe Vrillon, Elsa Bertrand, Marie Goubeaud, Hélène Catala, Johanne Germain, Nadéra Ainaoui, Marie Rafiq, Leonor Nogueira, François Mouton-Liger, Mélanie Planton, Anne-Sophie Salabert, Anne Hitzel, Déborah Méligne, Laurence Jasse, Benjamine Sarton, Stein Silva, Béatrice Lemesle, Patrice Péran, Pierre Payoux, Claire Thalamas, Claire Paquet, Jérémie Pariente
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103626- (2024)
Background: PET imaging of the translocator protein (TSPO) is used to assess in vivo brain inflammation. One of the main methodological issues with this method is the allelic dependence of the radiotracer affinity. In Alzheimer’s disease (AD), prev
Externí odkaz:
https://doaj.org/article/3f98282c7a774b81abd90595d8a333d4
Autor:
Agathe Vrillon, François Mouton-Liger, Matthieu Martinet, Emmanuel Cognat, Claire Hourregue, Julien Dumurgier, Elodie Bouaziz-Amar, Ann Brinkmalm, Kaj Blennow, Henrik Zetterberg, Jacques Hugon, Claire Paquet
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-11 (2022)
Abstract Background Synaptic dysfunction is an early core feature of Alzheimer’s disease (AD), closely associated with cognitive symptoms. Neuregulin 1 (NRG1) is a growth and differentiation factor with a key role in the development and maintenance
Externí odkaz:
https://doaj.org/article/041e8a55706645c0bccada9c89ee30db
Autor:
Karl Götze, Agathe Vrillon, Elodie Bouaziz-Amar, François Mouton-Liger, Jacques Hugon, Matthieu Martinet, Julien Dumurgier, Emmanuel Cognat, Henrik Zetterberg, Kaj Blennow, Claire Hourrègue, Claire Paquet, Matthieu Lilamand
Publikováno v:
Neurobiology of Disease, Vol 176, Iss , Pp 105937- (2023)
Objective: To explore the accuracy of plasma neurofilament light chain (NfL) as a biomarker for diagnosis and staging of cognitive impairment, in a large cohort with of previously diagnosed patients in clinical practice. Methods: Retrospective, cross
Externí odkaz:
https://doaj.org/article/9cd361e53791475ba1a459004f177c11
Autor:
François Mouton-Liger, Julien Dumurgier, Emmanuel Cognat, Claire Hourregue, Henrik Zetterberg, Hugo Vanderstichele, Eugeen Vanmechelen, Elodie Bouaziz-Amar, Kaj Blennow, Jacques Hugon, Claire Paquet
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-10 (2020)
Abstract Background The presynaptic protein neuregulin1 (NRG1) is cleaved by beta-site APP cleaving enzyme 1 (BACE1) in a similar way as amyloid precursor protein (APP) NRG1 can activate post-synaptic receptor tyrosine-protein kinase erbB4 (ErbB4) an
Externí odkaz:
https://doaj.org/article/8684adc4a477497daf12a79dafe645b7
Autor:
Matthieu Lilamand, Baptiste Porte, Emmanuel Cognat, Jacques Hugon, François Mouton-Liger, Claire Paquet
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-10 (2020)
Abstract Background Brain amyloid deposition and neurofibrillary tangles in Alzheimer’s disease (AD) are associated with complex neuroinflammatory reactions such as microglial activation and cytokine production. Glucose metabolism is closely relate
Externí odkaz:
https://doaj.org/article/9018620cc7a64355ad53961e4d165a35
Autor:
Matthieu Lilamand, François Mouton-Liger, Emmanuelle Di Valentin, Marta Sànchez Ortiz, Claire Paquet
Publikováno v:
Frontiers in Nutrition, Vol 8 (2022)
Alzheimer's disease (AD) is the most frequent age-related neurodegenerative disorder, with no curative treatment available so far. Alongside the brain deposition of β-amyloid peptide and hyperphosphorylated tau, neuroinflammation triggered by the in
Externí odkaz:
https://doaj.org/article/b9c4a98ba1c84d779bf2be7b3938d3fd
Publikováno v:
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-10 (2017)
Abstract Background Brain lesions in Alzheimer’s disease (AD) are characterized by Aβ accumulation, neurofibrillary tangles, and synaptic and neuronal vanishing. According to the amyloid cascade hypothesis, Aβ1-42 oligomers could trigger a neurot
Externí odkaz:
https://doaj.org/article/84e9262a40074091a1a24d0a568f4a2b
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Alzheimer’s disease (AD) is marked by memory disturbances followed by aphasia, apraxia and agnosia. Brain lesions include the accumulation of the amyloid peptide in extracellular plaques, neurofibrillary tangles with abnormally phosphorylated tau p
Externí odkaz:
https://doaj.org/article/379187ef76e24a49a5a1af62138244b8
Autor:
Thomas G. McWilliams, Erica Barini, Risto Pohjolan-Pirhonen, Simon P. Brooks, François Singh, Sophie Burel, Kristin Balk, Atul Kumar, Lambert Montava-Garriga, Alan R. Prescott, Sidi Mohamed Hassoun, François Mouton-Liger, Graeme Ball, Rachel Hills, Axel Knebel, Ayse Ulusoy, Donato A. Di Monte, Jevgenia Tamjar, Odetta Antico, Kyle Fears, Laura Smith, Riccardo Brambilla, Eino Palin, Miko Valori, Johanna Eerola-Rautio, Pentti Tienari, Olga Corti, Stephen B. Dunnett, Ian G. Ganley, Anu Suomalainen, Miratul M. K. Muqit
Publikováno v:
Open Biology, Vol 8, Iss 11 (2018)
Mutations in PINK1 and Parkin result in autosomal recessive Parkinson's disease (PD). Cell culture and in vitro studies have elaborated the PINK1-dependent regulation of Parkin and defined how this dyad orchestrates the elimination of damaged mitocho
Externí odkaz:
https://doaj.org/article/1d714fdf77f7434a8620cf73ff0a6aee