Zobrazeno 1 - 10
of 98
pro vyhledávání: '"François Moreau-Gaudry"'
Autor:
Samuel Amintas, Grégoire Cullot, Mehdi Boubaddi, Julie Rébillard, Laura Karembe, Béatrice Turcq, Valérie Prouzet-Mauléon, Aurélie Bedel, François Moreau-Gaudry, David Cappellen, Sandrine Dabernat
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-11 (2024)
Abstract Background The clustered regulatory interspaced short palindromic repeats (CRISPR)-Cas13a system has strong potential for highly sensitive detection of exogenous sequences. The detection of KRAS G12 point mutations with low allele frequencie
Externí odkaz:
https://doaj.org/article/8dc8ff30f63041339c691b909a112cf3
Autor:
Samuel Amintas, Pauline Beaumont, Charles Dupin, Isabelle Moranvillier, Isabelle Lamrissi, Elie Patel, Benjamin Fernandez, Alice Bibeyran, Julian Boutin, Tristan Richard, Stéphanie Krisa, François Moreau-Gaudry, Aurélie Bedel, David Cappellen, Benoît Pinson, Véronique Vendrely, Sandrine Dabernat
Publikováno v:
Journal of Functional Foods, Vol 99, Iss , Pp 105345- (2022)
Resveratrol belongs to the Bioactive Food Component (BFC) family. It seems admitted that its cytotoxic action impacts tumor cells and spares healthy cells, but the published proofs remain rare. We hypothesized that cells may differentially metabolize
Externí odkaz:
https://doaj.org/article/a6b60731bfbd48399c87283fc03376bc
Autor:
Etienne Buscail, Alexandre Chauvet, Pascaline Quincy, Olivier Degrandi, Camille Buscail, Isabelle Lamrissi, Isabelle Moranvillier, Charline Caumont, Severine Verdon, Alain Brisson, Marion Marty, Laurence Chiche, Christophe Laurent, Veronique Vendrely, François Moreau-Gaudry, Aurelie Bedel, Sandrine Dabernat
Publikováno v:
Translational Oncology, Vol 12, Iss 11, Pp 1395-1403 (2019)
Tumor-released extracellular vesicles (EVs) contain tumor-specific cargo distinguishing them from healthy EVs, and making them eligible as circulating biomarkers. Glypican 1 (GPC1)-positive exosome relevance as liquid biopsy elements is still debated
Externí odkaz:
https://doaj.org/article/447e7ab005934ffa9855c3175c2772d0
Autor:
Etienne Buscail, Laurence Chiche, Christophe Laurent, Véronique Vendrely, Quentin Denost, Jérôme Denis, Matthieu Thumerel, Jean‐Marc Lacorte, Aurélie Bedel, François Moreau‐Gaudry, Sandrine Dabernat, Catherine Alix‐Panabières
Publikováno v:
Molecular Oncology, Vol 13, Iss 9, Pp 1811-1826 (2019)
Circulating tumor cell (CTC) detection and numeration are becoming part of the common clinical practice, especially for breast, colon, and prostate cancer. However, their paucity in peripheral blood samples is an obstacle for their identification. Se
Externí odkaz:
https://doaj.org/article/ff9f46931feb4cd7bedc856d058577a1
Autor:
Grégoire Cullot, Julian Boutin, Jérôme Toutain, Florence Prat, Perrine Pennamen, Caroline Rooryck, Martin Teichmann, Emilie Rousseau, Isabelle Lamrissi-Garcia, Véronique Guyonnet-Duperat, Alice Bibeyran, Magalie Lalanne, Valérie Prouzet-Mauléon, Béatrice Turcq, Cécile Ged, Jean-Marc Blouin, Emmanuel Richard, Sandrine Dabernat, François Moreau-Gaudry, Aurélie Bedel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
CRISPR-Cas9 has been rapidly adopted to generate cell line models of disease. Here the authors show, while attempting to establish a congenital erythropoietic porphyria model, unexpected chromosome truncations generated by a p53-dependent mechanism.
Externí odkaz:
https://doaj.org/article/3a225f969b444010a97c3369c573fb50
Next-Generation Cancer Biomarkers: Extracellular Vesicle DNA as a Circulating Surrogate of Tumor DNA
Autor:
Samuel Amintas, Véronique Vendrely, Charles Dupin, Louis Buscail, Christophe Laurent, Barbara Bournet, Jean-Philippe Merlio, Aurélie Bedel, François Moreau-Gaudry, Julian Boutin, Sandrine Dabernat, Etienne Buscail
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Extracellular vesicles (EVs) are produced by healthy tissues and tumor cells and are released in various bodily fluids, including blood. They are limited by bilayer phospholipidic membranes, and they carry a rich content in biomolecules. Their releas
Externí odkaz:
https://doaj.org/article/8b80cec79fc643f28a9fb04db7bebb51
Autor:
Marie-Lise Bats, Benoit Rucheton, Tara Fleur, Arthur Orieux, Clément Chemin, Sébastien Rubin, Brigitte Colombies, Arnaud Desclaux, Claire Rivoisy, Etienne Mériglier, Etienne Rivière, Alexandre Boyer, Didier Gruson, Isabelle Pellegrin, Pascale Trimoulet, Isabelle Garrigue, Rana Alkouri, Charles Dupin, François Moreau-Gaudry, Aurélie Bedel, Sandrine Dabernat
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0250956 (2021)
Clinical and laboratory predictors of COVID-19 severity are now well described and combined to propose mortality or severity scores. However, they all necessitate saturable equipment such as scanners, or procedures difficult to implement such as bloo
Externí odkaz:
https://doaj.org/article/2a22f9729254448980bcec7a73447488
Autor:
Julie Estève, Jean-Marc Blouin, Magalie Lalanne, Lamia Azzi-Martin, Pierre Dubus, Audrey Bidet, Jérôme Harambat, Brigitte Llanas, Isabelle Moranvillier, Aurélie Bedel, François Moreau-Gaudry, Emmanuel Richard
Publikováno v:
Stem Cell Research, Vol 38, Iss , Pp - (2019)
Primary hyperoxaluria type 1 (PH1) is a rare autosomal recessive disorder of the liver metabolism due to functional deficiency of the peroxisomal enzyme alanine:glyoxylate aminotransferase (AGT). AGT deficiency results in overproduction of oxalate wh
Externí odkaz:
https://doaj.org/article/476d4c6bd93d4628976d502a4aa2a62c
Autor:
Samuel Amintas, Aurélie Bedel, François Moreau-Gaudry, Julian Boutin, Louis Buscail, Jean-Philippe Merlio, Véronique Vendrely, Sandrine Dabernat, Etienne Buscail
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2653 (2020)
The presence of circulating tumor cells (CTCs) and CTC clusters, also known as tumor microemboli, in biological fluids has long been described. Intensive research on single CTCs has made a significant contribution in understanding tumor invasion, met
Externí odkaz:
https://doaj.org/article/b55b9e906f8a4afeb112aaf0eade84ad
Autor:
Aurélie Bedel, Jean-Max Pasquet, Eric Lippert, Miguel Taillepierre, Valérie Lagarde, Sandrine Dabernat, Pierre Dubus, Lucie Charaf, François Beliveau, Hubert de Verneuil, Emmanuel Richard, François-Xavier Mahon, François Moreau-Gaudry
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71596 (2013)
Chronic myeloid leukemia disease (CML) found effective therapy by treating patients with tyrosine kinase inhibitors (TKI), which suppress the BCR-ABL1 oncogene activity. However, the majority of patients achieving remission with TKI still have molecu
Externí odkaz:
https://doaj.org/article/20baab42acec45e29178f6ba8784b5bb