Zobrazeno 1 - 10
of 34
pro vyhledávání: '"François Lehembre"'
Autor:
Laetitia Pouzol, Anna Sassi, Nadège Baumlin, Mélanie Tunis, Daniel S. Strasser, François Lehembre, Marianne M. Martinic
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Loss of control in the trafficking of immune cells to the inflamed lung tissue contributes to the pathogenesis of life-threatening acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS). Targeting CXCR7 has been
Externí odkaz:
https://doaj.org/article/87143f960dcd406b842cdbeee31d0c1a
Autor:
Sun-Jin Kim, Jang Seong Kim, Seung Wook Kim, Emily Brantley, Seok Joong Yun, Junqin He, Marva Maya, Fahao Zhang, Qiuyu Wu, François Lehembre, Urs Regenass, Isaiah J. Fidler
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 2, Pp 167-179 (2011)
Potential treatments for ovarian cancers that have become resistant to standard chemotherapies include modulators of tumor cell survival, such as endothelin receptor (ETR) antagonist. We investigated the therapeutic efficacy of the dual ETR antagonis
Externí odkaz:
https://doaj.org/article/7ccd198f6b6b45db91c654b062b68a9e
Autor:
Isaiah J. Fidler, Urs Regenass, François Lehembre, Robert R. Langley, Charles A. Conrad, W.K. Alfred Yung, Jeffrey S. Weinberg, Kenneth Aldape, Qiuyu Wu, Junqin He, Hyun Jin Choi, Mark Seungwook Kim, Ho Jeong Lee, Sun-Jin Kim
Supplementary Figure 4. Macitentan suppresses activation of AKT and MAPK signaling pathways on glioma cells and tumor-associated endothelial cells in TMZresistant D54Res glioblastomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d93d257527c3b72175092b2de2ec8f0
https://doi.org/10.1158/1078-0432.22460225
https://doi.org/10.1158/1078-0432.22460225
Autor:
Isaiah J. Fidler, Urs Regenass, François Lehembre, Robert R. Langley, Charles A. Conrad, W.K. Alfred Yung, Jeffrey S. Weinberg, Kenneth Aldape, Qiuyu Wu, Junqin He, Hyun Jin Choi, Mark Seungwook Kim, Ho Jeong Lee, Sun-Jin Kim
Legends to Supplementary Figures 1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371be4ceabbf22609593d69e30404775
https://doi.org/10.1158/1078-0432.22460216
https://doi.org/10.1158/1078-0432.22460216
Autor:
Isaiah J. Fidler, Urs Regenass, François Lehembre, Robert R. Langley, Charles A. Conrad, W.K. Alfred Yung, Jeffrey S. Weinberg, Kenneth Aldape, Qiuyu Wu, Junqin He, Hyun Jin Choi, Mark Seungwook Kim, Ho Jeong Lee, Sun-Jin Kim
Supplementary Figure 1. Combination therapy with macitentan and TMZ leads to regression of established LN-229 glioblastomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9618b2f61084ccb15683f3a90b92d095
https://doi.org/10.1158/1078-0432.22460234
https://doi.org/10.1158/1078-0432.22460234
Autor:
Isaiah J. Fidler, Urs Regenass, François Lehembre, Robert R. Langley, Charles A. Conrad, W.K. Alfred Yung, Jeffrey S. Weinberg, Kenneth Aldape, Qiuyu Wu, Junqin He, Hyun Jin Choi, Mark Seungwook Kim, Ho Jeong Lee, Sun-Jin Kim
Supplementary Figure 3. Combination therapy with macitentan and TMZ produces durable responses in mice with established LN-229 glioblastomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07519c5f9f524233403ce905e88e62d8
https://doi.org/10.1158/1078-0432.22460228.v1
https://doi.org/10.1158/1078-0432.22460228.v1
Autor:
Isaiah J. Fidler, Urs Regenass, François Lehembre, Robert R. Langley, Charles A. Conrad, W.K. Alfred Yung, Jeffrey S. Weinberg, Kenneth Aldape, Qiuyu Wu, Junqin He, Hyun Jin Choi, Mark Seungwook Kim, Ho Jeong Lee, Sun-Jin Kim
Purpose: The objective of the study was to determine whether astrocytes and brain endothelial cells protect glioma cells from temozolomide through an endothelin-dependent signaling mechanism and to examine the therapeutic efficacy of the dual endothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99a6be4bafc2c5a4bfba5ed2e223f46
https://doi.org/10.1158/1078-0432.c.6524432
https://doi.org/10.1158/1078-0432.c.6524432
Autor:
Isaiah J. Fidler, Urs Regenass, François Lehembre, Robert R. Langley, Charles A. Conrad, W.K. Alfred Yung, Jeffrey S. Weinberg, Kenneth Aldape, Qiuyu Wu, Junqin He, Hyun Jin Choi, Mark Seungwook Kim, Ho Jeong Lee, Sun-Jin Kim
Supplementary Figure 6. Effects of treatment on glioblastoma-associated blood vessels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611322570445401221d1c26d3c3bc254
https://doi.org/10.1158/1078-0432.22460219.v1
https://doi.org/10.1158/1078-0432.22460219.v1
Autor:
Isaiah J. Fidler, Urs Regenass, François Lehembre, Robert R. Langley, Charles A. Conrad, W.K. Alfred Yung, Jeffrey S. Weinberg, Kenneth Aldape, Qiuyu Wu, Junqin He, Hyun Jin Choi, Mark Seungwook Kim, Ho Jeong Lee, Sun-Jin Kim
Supplementary Figure 2. Combination therapy with macitentan plus TMZ eradicates experimental glioblastomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270690700adb4c3fbe9c15dc902a8861
https://doi.org/10.1158/1078-0432.22460231
https://doi.org/10.1158/1078-0432.22460231
Autor:
Sylvia Richard-Bildstein, Gabriel Schäfer, Laetitia Pouzol, Eleanor Lindenberg, François Lehembre, Hamed Aissaoui, Julien Pothier, Philippe Guerry, Carmela Gnerre
Publikováno v:
Journal of Medicinal Chemistry. 63:15864-15882
The chemokine receptor CXCR7, also known as ACKR3, is a seven-transmembrane G-protein-coupled receptor (GPCR) involved in various pathologies such as neurological diseases, autoimmune diseases, and cancers. By binding and scavenging the chemokines CX