Výsledky vyhledávání - "François Kien"

Akademický článek

Ezrin interacts with the SARS coronavirus Spike protein and restrains infection at the entry stage.

Autor: Jean Kaoru Millet, François Kien, Chung-Yan Cheung, Yu-Lam Siu, Wing-Lim Chan, Huiying Li, Hiu-Lan Leung, Martial Jaume, Roberto Bruzzone, Joseph S Malik Peiris, Ralf Marius Altmeyer, Béatrice Nal

Publikováno v: PLoS ONE, Vol 7, Iss 11, p e49566 (2012)

BackgroundEntry of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) and its envelope fusion with host cell membrane are controlled by a series of complex molecular mechanisms, largely dependent on the viral envelope glycoprotein Spike (S). Th

Externí odkaz: https://doaj.org/article/06b9d55ced654719b4caa76f17b3525a

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Cell Cycle-independent Role of Cyclin D3 in Host Restriction of Influenza Virus Infection

Autor: Sumana Sanyal, Chris Ka Pun Mok, François Kien, Roberto Bruzzone, Ying Fan, Béatrice Nal, Yang Zhang, Michael C. W. Chan

Publikováno v: Journal of Biological Chemistry
The Journal of Biological Chemistry

To identify new host factors that modulate the replication of influenza A virus, we performed a yeast two-hybrid screen using the cytoplasmic tail of matrix protein 2 from the highly pathogenic H5N1 strain. The screen revealed a high-score interactio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbe843fcb95109d8aeed119c28b1bbb

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Antibodies against trimeric S glycoprotein protect hamsters against SARS-CoV challenge despite their capacity to mediate FcγRII-dependent entry into B cells in vitro

Autor: Sherif R. Zaki, Anjeanette Roberts, Yan Chung Cheung, Ralf Altmeyer, Yiu Wing Kam, Jane Tse, Shui Ling Chu, Jeannette Guarner, Kanta Subbarao, François Kien, Béatrice Nal, Leatrice Vogel, Elaine W. Lamirande, Malik Peiris

Publikováno v: Vaccine

Vaccine-induced antibodies can prevent or, in the case of feline infectious peritonitis virus, aggravate infections by coronaviruses. We investigated whether a recombinant native full-length S-protein trimer (triSpike) of severe acute respiratory syn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468565f383f341617e4e80c0abb36046
https://doi.org/10.1016/j.vaccine.2006.08.011

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Comparative immunogenicity analysis of modified vaccinia Ankara vectors expressing native or modified forms of hepatitis C virus E1 and E2 glycoproteins

Autor: Birke Bartosch, François Kien, Jean-Daniel Abraham, Thomas Baumert, Nourredine Himoudi, Jean-Luc Berland, Gláucia Paranhos-Baccalà, Catherine Schuster, Marie Paule Kieny, Geneviève Inchauspé, Audrey Codran

Publikováno v: Vaccine. 22:3917-3928

We have evaluated in C57/Bl6 and HLA-A2.1 transgenic mice the immunogenicity of three MVA vectors expressing either native HCV E1E2 polyprotein, truncated and secreted E1 (E'1(311)) and E2 (E'2(661)) proteins, or a chimeric E1E2 heterodimer presented

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ea081fbb3bdbf2bad13485578c2b66
https://doi.org/10.1016/j.vaccine.2004.04.005

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Hepatitis C virus IRES efficiency is unaffected by the genomic RNA 3′NTR even in the presence of viral structural or non-structural proteins

Autor: Marie Paule Kieny, Maria Dimitrova, Catherine Schuster, Isabelle Imbert, François Kien

Publikováno v: Journal of General Virology. 84:1549-1557

Hepatitis C virus (HCV) translation is mediated by an IRES structure. Instead of a poly(A) tail, the 3' end of the genome contains a tripartite 3'NTR composed of a non-conserved region, a polypyrimidine tract and a highly conserved stretch of 98 nt,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd34d9fa4159fff831545ee90f1d06a
https://doi.org/10.1099/vir.0.18907-0

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Analysis of the subcellular localization of hepatitis C virus E2 glycoprotein in live cells using EGFP fusion proteins

Autor: Marie Paule Kieny, Jean-Daniel Abraham, François Kien, Catherine Schuster

Publikováno v: Journal of General Virology. 84:561-566

Hepatitis C virus (HCV) E1 and E2 glycoproteins assemble intracellularly to form a non-covalently linked heterodimer, which is retained in the endoplasmic reticulum (ER). To study the subcellular localization of E2 in live cells, the enhanced green f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab1ce02130700f2521b474169de4a9b
https://doi.org/10.1099/vir.0.18927-0

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Human annexin A6 interacts with influenza a virus protein M2 and negatively modulates infection

Autor: Kong San Tse, Leo L.M. Poon, Maxime Manière, François Kien, Yang Zhang, Huailiang Ma, Nadège Lagarde, Béatrice Nal

Publikováno v: Europe PubMed Central

The influenza A virus M2 ion channel protein has the longest cytoplasmic tail (CT) among the three viral envelope proteins and is well conserved between different viral strains. It is accessible to the host cellular machinery after fusion with the en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e90e280a812b21dc3aaf79562b699c6b
http://hdl.handle.net/10722/161157

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Ezrin Interacts with the SARS Coronavirus Spike Protein and Restrains Infection at the Entry Stage

Autor: Joseph S. M. Peiris, Yu Lam Siu, Ralf Altmeyer, Roberto Bruzzone, François Kien, Huiying Li, Jean K. Millet, Béatrice Nal, Chung Yan Cheung, Wing Lim Chan, Martial Jaume, HL Leung

Publikováno v: PLOS ONE, 7(11):e49566
Plos One 11 (7), e49566. (2012)
PLoS ONE
PLoS ONE, Public Library of Science, 2012, 7 (11), pp.e49566. ⟨10.1371/journal.pone.0049566⟩
PLoS ONE, 2012, 7 (11), pp.e49566. ⟨10.1371/journal.pone.0049566⟩
PLoS ONE, Vol 7, Iss 11, p e49566 (2012)

© 2012 Millet et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020aa00b9ffce3332b27a881345b0801
https://repository.publisso.de/resource/frl:6420436

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Anti-severe acute respiratory syndrome coronavirus spike antibodies trigger infection of human immune cells via a pH- and cysteine protease-independent FcγR pathway

Autor: J. S. Malik Peiris, Martial Jaume, Ralf Altmeyer, François Kien, Isabelle Dutry, Roberto Bruzzone, Benoit Callendret, Chung Y. Cheung, HL Leung, Marc Daëron, Nicolas Escriou, Ming S. Yip, Ping H. Li, Béatrice Nal

Publikováno v: Journal of Virology
Europe PubMed Central

Public health measures successfully contained outbreaks of the severe acute respiratory syndrome coronavirus (SARS-CoV) infection. However, the precursor of the SARS-CoV remains in its natural bat reservoir, and reemergence of a human-adapted SARS-li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0714e5c1c04074918423cc3b4d4d2e56
https://pubmed.ncbi.nlm.nih.gov/21775467

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Identification of human annexin A6 as a novel cellular interactant of influenza A M2 protein: implications for influenza life cycle

Autor: Llm Poon, Jane Tse, Huailiang Ma, Béatrice Nal, François Kien, Yang Zhang

Publikováno v: BMC Proceedings, Vol 5, Iss Suppl 1, p P67 (2011)
Europe PubMed Central
BMC Proceedings

Background During its replication, influenza virus utilizes the host cellular machineries for many aspects of its life cycle. Characterization of such virus-host protein-protein interactions is a must to identify determinants of pathogenesis. The M2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3944ba3487b06d5d3438ae7af2ac97f
https://doi.org/10.1186/1753-6561-5-s1-p67

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