Zobrazeno 1 - 7
of 7
pro vyhledávání: '"François J. Roman"'
Publikováno v:
Journal of Integrative Neuroscience, Vol 23, Iss 5, p 92 (2024)
The evidence of brain–gut interconnections in Alzheimer’s disease (AD) opens novel avenues for the treatment of a pathology for which no definitive treatment exists. Gut microbiota and bacterial translocation may produce peripheral inflammation a
Externí odkaz:
https://doaj.org/article/c89a5ff6c4df45d2aedf8849d9f00d6a
Publikováno v:
Journal of Integrative Neuroscience, Vol 23, Iss 3, p 57 (2024)
Recently, novel non-pharmacological interventions, such as photobiomodulation (PBM) therapy, have shown promise for the treatment of Alzheimer’s disease (AD). This article outlines the translation from the preclinical to clinical stages of an innov
Externí odkaz:
https://doaj.org/article/897cf77769ae4ced8eb27c4aa08a7b01
Autor:
Yukihiro Noda, Kiyofumi Yamada, Taku Nagai, Pascal Romieu, Hung Manh Tran, François J. Roman, Hiroyuki Kamei, Toshitaka Nabeshima, Alexandre Urani, Tangui Maurice
Publikováno v:
European journal of pharmacology. 486(2)
Treatment of depressive symptoms in patients suffering from neurodegenerative disorders remains a challenging issue, since few available antidepressants present an adequate efficacy during pathological aging. Previous reports suggested that selective
Publikováno v:
Behavioural brain research. 134(1-2)
This study examined the antidepressant efficacy of the selective sigma(1) receptor agonists igmesine or PRE-084 in mice injected intracerebroventricularly (i.c.v.) with beta(25-35)-amyloid peptide and submitted to the forced swim test. Beta(25-35) pe
Publikováno v:
Psychopharmacology. 163(1)
Activation of the neuronal sigma(1) (sigma(1)) receptor potentiates calcium mobilization, leading to effective modulation of postsynaptic responses to neurotransmitters. At the behavioral level, sigma(1) agonists modulate learning, response to stress
Publikováno v:
Brain research. 733(2)
A beneficial effect of sigma (sigma) agonists was previously described on several pharmacological models of learning impairments. We examined this effect in senescence-accelerated mice (SAM), which has been developed as a murine model of aging and co
Autor:
François J. Roman, Anneth Doherty, Maria Chovet, Jean Fioramonti, Helene Eutamene, Lionel Bueno, Vassilia Theodorou
Publikováno v:
Gastroenterology. 118:A376