Zobrazeno 1 - 10
of 71
pro vyhledávání: '"François Guérard"'
Autor:
Loris Roncali, Séverine Marionneau-Lambot, Charlotte Roy, Romain Eychenne, Sébastien Gouard, Sylvie Avril, Nicolas Chouin, Jérémie Riou, Mathilde Allard, Audrey Rousseau, François Guérard, François Hindré, Michel Chérel, Emmanuel Garcion
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105202- (2024)
Summary: Background: Glioblastoma (GB), the most aggressive brain cancer, remains a critical clinical challenge due to its resistance to conventional treatments. Here, we introduce a locoregional targeted-α-therapy (TAT) with the rat monoclonal anti
Externí odkaz:
https://doaj.org/article/c893b207ab6f4738b36ea397dd0319b1
Autor:
Justine Perrin, Marisa Capitao, Marie Mougin-Degraef, François Guérard, Alain Faivre-Chauvet, Latifa Rbah-Vidal, Joëlle Gaschet, Yannick Guilloux, Françoise Kraeber-Bodéré, Michel Chérel, Jacques Barbet
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
The impressive development of cancer immunotherapy in the last few years originates from a more precise understanding of control mechanisms in the immune system leading to the discovery of new targets and new therapeutic tools. Since different stages
Externí odkaz:
https://doaj.org/article/917a62510146415d8739dae10daa49e9
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 906 (2021)
Among all existing radionuclides, only a few are of interest for therapeutic applications and more specifically for targeted alpha therapy (TAT). From this selection, actinium-225, astatine-211, bismuth-212, bismuth-213, lead-212, radium-223, terbium
Externí odkaz:
https://doaj.org/article/71e01208e20a4ebd8aa898559bef0639
Autor:
Sébastien Gouard, Catherine Maurel, Séverine Marionneau-Lambot, Delphine Dansette, Clément Bailly, François Guérard, Nicolas Chouin, Ferid Haddad, Cyril Alliot, Joëlle Gaschet, Romain Eychenne, Françoise Kraeber-Bodéré, Michel Chérel
Publikováno v:
Cancers, Vol 12, Iss 9, p 2721 (2020)
Despite therapeutic progress in recent years with the introduction of targeted therapies (daratumumab, elotuzumab), multiple myeloma remains an incurable cancer. The question is therefore to investigate the potential of targeted alpha therapy, combin
Externí odkaz:
https://doaj.org/article/2e4d22a2ffbb4a3cb77aaa9418d641c5
Autor:
Françoise Kraeber-Bodéré, Caroline Rousseau, Caroline Bodet-Milin, Cédric Mathieu, François Guérard, Eric Frampas, Thomas Carlier, Nicolas Chouin, Ferid Haddad, Jean-François Chatal, Alain Faivre-Chauvet, Michel Chérel, Jacques Barbet
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 2, Pp 3932-3954 (2015)
This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the lev
Externí odkaz:
https://doaj.org/article/48f3001a0dda4beab5e565506ebb1458
Autor:
Clément Bailly, Sébastien Gouard, François Guérard, Benjamin Chalopin, Thomas Carlier, Alain Faivre-Chauvet, Patricia Remaud-Le Saëc, Mickaël Bourgeois, Nicolas Chouin, Latifa Rbah-Vidal, Raphaël Tripier, Ferid Haddad, Françoise Kraeber-Bodéré, Caroline Bodet-Milin, Michel Chérel
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2564 (2019)
Although positron emission tomography (PET) imaging with 18-Fluorodeoxyglucose (18F-FDG) is a promising technique in multiple myeloma (MM), the development of other radiopharmaceuticals seems relevant. CD138 is currently used as a standard marker for
Externí odkaz:
https://doaj.org/article/122cd9e6f42646f0947532ad87f73e51
Autor:
Clément Bailly, Rodolphe Leforestier, Bastien Jamet, Thomas Carlier, Mickael Bourgeois, François Guérard, Cyrille Touzeau, Philippe Moreau, Michel Chérel, Françoise Kraeber-Bodéré, Caroline Bodet-Milin
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 2, p 445 (2017)
Multiple myeloma (MM) is a hematological neoplasm characterized by the clonal proliferation of malignant plasma cells in the bone marrow. MM results in diffuse or focal bone infiltration and extramedullary lesions. Over the past two decades, advances
Externí odkaz:
https://doaj.org/article/9c3949fb0ca04ce9ac7647c6d25515dc
Autor:
Clément Bailly, Pierre-François Cléry, Alain Faivre-Chauvet, Mickael Bourgeois, François Guérard, Ferid Haddad, Jacques Barbet, Michel Chérel, Françoise Kraeber-Bodéré, Thomas Carlier, Caroline Bodet-Milin
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 1, p 57 (2016)
Recent advances in molecular characterization of tumors have allowed identification of new molecular targets on tumor cells or biomarkers. In medical practice, the identification of these biomarkers slowly but surely becomes a prerequisite before any
Externí odkaz:
https://doaj.org/article/edd51fca2164481ea92de0dc381be818
Autor:
Gilles Montavon, François Guérard, Jean-François Gestin, Nicolas Galland, Romain Eychenne, Lu Liu, Clémence Maingueneau
Publikováno v:
Accounts of Chemical Research
Accounts of Chemical Research, American Chemical Society, 2021, 54 (16), pp.3264. ⟨10.1021/acs.accounts.1c00327⟩
Accounts of Chemical Research, 2021, 54 (16), pp.3264. ⟨10.1021/acs.accounts.1c00327⟩
Accounts of Chemical Research, American Chemical Society, 2021, 54 (16), pp.3264. ⟨10.1021/acs.accounts.1c00327⟩
Accounts of Chemical Research, 2021, 54 (16), pp.3264. ⟨10.1021/acs.accounts.1c00327⟩
ConspectusAstatine (At) is the rarest on Earth of all naturally occurring elements, situated below iodine in the periodic table. While only short-lived isotopes (t1/2 ≤ 8.1 h) are known, 211At is the object of growing attention due to its emission