Zobrazeno 1 - 10
of 24
pro vyhledávání: '"François Fossiez"'
Autor:
Silvia Schnyder-Candrian, Isabelle Couillin, François Fossiez, Valérie F. J. Quesniaux, Dieudonnée Togbe, Frank Brombacher, Bruno Schnyder, Bernhard Ryffel, Isabelle Mercier
Publikováno v:
The Journal of Experimental Medicine
T helper (Th)17 cells producing interleukin (IL)-17 play a role in autoimmune and allergic inflammation. Here, we show that IL-23 induces IL-17 in the lung and IL-17 is required during antigen sensitization to develop allergic asthma, as shown in IL-
Autor:
Eric Tartour, Hervé Bachelez, Francette Jean Louis, Sophie Camilleri-Broët, Wolf H. Fridman, Arnaud Ciree, Béatrice Flageul, M. Oster, François Fossiez, Laurence Michel, Patricia Senet
Publikováno v:
International Journal of Cancer. 112:113-120
Interleukin-17 (IL-17) is a proinflammatory cytokine mainly produced by activated CD4+ CD45RO T cells. In mice, we have demonstrated that, depending on the model, IL-17 may act as a tumor growth-promoting or -inhibiting factor. In order to address th
Autor:
Arnaud Ciree, François Fossiez, Virginie Vives, Alain Gey, Fabrice Benchetrit, Wolf H. Fridman, Eric Tartour, Guy Warnier, Nacilla Haicheur, Catherine Sautès-Fridman
Publikováno v:
Blood. 99:2114-2121
Interleukin 17 (IL-17) is a proinflammatory cytokine produced by activated CD4+ memory T cells. We previously showed that IL-17 increased the growth rate of human cervical tumors transplanted into athymic nude mice. To address the possible role of T
Autor:
S. Ho, Serge Lebecque, Hector Martinez-Valdez, François Fossiez, Jean-François Nicolas, M.J. Maat, Florence Malisan, E. Peyron, Christiane Guret, V. Frances
Publikováno v:
Journal of Autoimmunity. 15:459-468
We identified, cloned, and biochemically characterized the full-length cDNAs encoding the heavy and light chains of a human monoclonal antibody (mAb) from the Epstein-Barr virus (EBV)-cell line P22. The cell line P22, which originated from a patient
Autor:
François Fossiez, Pierre-André Guerne, Patrick Garnero, Martine Chabaud, Pierre Miossec, Jean-Michel Dayer
Publikováno v:
Cytokine. 12:1092-1099
Interleukin (IL-)17 is a T cell-derived pro-inflammatory cytokine produced by RA synovium. We studied the role of IL-17 in the synovium cytokine network to determine whether it can influence the inflammatory and destructive pattern characteristic of
Autor:
Paul-Henri Cugnenc, François Fossiez, Anne Berger, Catherine Sautès-Fridman, Virginie Vives, Wolf H. Fridman, Franck Pages, Eric Tartour
Publikováno v:
Immunology Letters. 68:135-139
The local immune reactions may influence the clinical outcome of human tumors. In carcinoma of the cervix, high gene expression of IL6 with tumor invasiveness whereas lack of gene expression of IFNbeta is correlated with poor prognosis. In colorectal
Autor:
Brigitte Rosenwirth, François Fossiez, Serge Lebecque, Mathias Thurau, Andrea Knappe, Jonathan L. Heeney, Jacques Banchereau, Sabine Wittmann, Eva-Maria Kuhn, Helmut Fickenscher, Bernhard Fleckenstein, Christian Hiller, Henk Niphuis
Publikováno v:
Journal of Virology. 72:5797-5801
In comparison to wild-type herpesvirus saimiri, viral interleukin-17 gene knockout mutants have unaltered behavior regarding viral replication, T-cell transformation in vitro, and pathogenicity in cottontop tamarins. Thus, this gene is not required f
Autor:
François Fossiez, Jacques Banchereau, Richard Murray, Cees Van Kooten, Pierre Garrone, Serge Lebecque
Publikováno v:
International Reviews of Immunology. 16:541-551
The particular interest of IL-17, a homodimeric cytokine of about 32 kDa, is the strict requirement for an activation signal to induce its expression from a rather restricted set of cells, human memory T cells or mouse alpha beta TCR+CD4-CD8- thymocy
Publikováno v:
Scandinavian Journal of Immunology. 46:413-418
Neutralizing autoantibodies to interleukin (IL)-1 alpha were detected in a subset of chronic polyarthritis patients characterized by an increased proportion of patients with primary Sjögren's syndrome or self-limiting inflammatory arthritis, disease
Autor:
Marie-Geneviève Mattei, Odette de Bouteiller, Isabelle Fugier-Vivier, Christiane Guret, Jacques Banchereau, Yong-Jun Liu, Serge Lebecque, Eric Garcia, Smina Ait-Yahia, François Fossiez
Publikováno v:
European Journal of Immunology. 27:1824-1827
RP105 is a 105-kDa type I membrane protein of the leucine-rich repeat (LRR) family. Anti-RP105 sensitizes B cells to antigen-receptor-mediated apoptosis, but protects B cells from radiation-induced apoptosis and stimulates B cell proliferation. The s