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Publikováno v:
Peptides
Peptides, Elsevier, 1993, 14 (5), pp.983-989
Peptides, Elsevier, 1993, 14 (5), pp.983-989
Neurotensin and neuromedin N are two biologically active, related peptides that are encoded in the same precursor molecule. In the rat, the precursor consists of a 169-residue polypeptide containing in its C- terminal region one copy each of neuroten
Publikováno v:
Annals of the New York Academy of Sciences. 668
Publikováno v:
Brain Research
Brain Research, Elsevier, 1989, 500 (1-2), pp.193-198
Brain Research, Elsevier, 1989, 500 (1-2), pp.193-198
Neuromedin N is a hexapeptide that shares a 4 amino acid homology with the C-terminus of neurotensin and exhibits neurotensin-like effects in the central nervous system. Both peptides were recently shown to be encoded in the same precursor molecule.
Publikováno v:
Biochemical and biophysical research communications. 161(3)
Neurotensin, bradykinin and somatostatin inhibited in a time- and concentration-dependent manner prostaglandin E1- or forskolin-stimulated cAMP production in neuroblastoma N1E115 cells. Cell treatment with 1 microgram/ml pertussis toxin for 6 hours r