Zobrazeno 1 - 10
of 99
pro vyhledávání: '"François D. Boussin"'
Autor:
Amandine Bery, Olivier Etienne, Laura Mouton, Sofiane Mokrani, Christine Granotier-Beckers, Laurent R. Gauthier, Justyne Feat-Vetel, Thierry Kortulewski, Elodie A. Pérès, Chantal Desmaze, Philippe Lestaveal, Vilma Barroca, Antony Laugeray, Fawzi Boumezbeur, Vincent Abramovski, Stéphane Mortaud, Arnaud Menuet, Denis Le Bihan, Jean-Pierre de Villartay, François D. Boussin
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112342- (2023)
Summary: XLF/Cernunnos is a component of the ligation complex used in classical non-homologous end-joining (cNHEJ), a major DNA double-strand break (DSB) repair pathway. We report neurodevelopmental delays and significant behavioral alterations assoc
Externí odkaz:
https://doaj.org/article/932eb1262b3c484399e5f2d802035f1e
Autor:
Marc-André Mouthon, Lise Morizur, Léa Dutour, Donovan Pineau, Thierry Kortulewski, François D. Boussin
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101784- (2020)
Summary: The production of neurons from neural stem cells (NSCs) persists throughout life in the mouse ventricular-subventricular zone (V-SVZ). We have previously reported that NSCs from adult V-SVZ are contained in cell populations expressing the ca
Externí odkaz:
https://doaj.org/article/9e6b35aed5df4132b10eabc8c39e3dff
Autor:
Lise Morizur, Alexandra Chicheportiche, Laurent R. Gauthier, Mathieu Daynac, François D. Boussin, Marc-André Mouthon
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 565-577 (2018)
Summary: Deciphering the mechanisms that regulate the quiescence of adult neural stem cells (NSCs) is crucial for the development of therapeutic strategies based on the stimulation of their endogenous regenerative potential in the damaged brain. We s
Externí odkaz:
https://doaj.org/article/f6de8799444748aa8c0413d23111a340
Autor:
Mathieu Daynac, Linda Tirou, Hélène Faure, Marc-André Mouthon, Laurent R. Gauthier, Heidi Hahn, François D. Boussin, Martial Ruat
Publikováno v:
Stem Cell Reports, Vol 7, Iss 4, Pp 735-748 (2016)
Identifying the mechanisms controlling quiescence and activation of neural stem cells (NSCs) is crucial for understanding brain repair. Here, we demonstrate that Hedgehog (Hh) signaling actively regulates different pools of quiescent and proliferativ
Externí odkaz:
https://doaj.org/article/27a6e426bd4940a6a9431b0a9d15ec0e
Autor:
Pascal Millet, Céline Silva Lages, Stéphane Haïk, Ewa Nowak, Isabelle Allemand, Christine Granotier, François D. Boussin
Publikováno v:
Neurobiology of Disease, Vol 19, Iss 1, Pp 57-65 (2005)
Amyloid-β peptide (Aβ), derived from the amyloid-β precursor protein (APP), plays a central role in the pathogenesis of Alzheimer's disease and induces neuronal apoptosis. Neural progenitor cells persist in the adult mammalian brain and continue t
Externí odkaz:
https://doaj.org/article/fb9bcad3ad564f3093440883f7f4be16
Autor:
Benoit Roch, Vincent Abramowski, Olivier Etienne, Stefania Musilli, Pierre David, Jean-Baptiste Charbonnier, Isabelle Callebaut, François D Boussin, Jean-Pierre de Villartay
Publikováno v:
eLife, Vol 10 (2021)
We developed an Xrcc4M61R separation of function mouse line to overcome the embryonic lethality of Xrcc4-deficient mice. XRCC4M61R protein does not interact with Xlf, thus obliterating XRCC4-Xlf filament formation while preserving the ability to stab
Externí odkaz:
https://doaj.org/article/9f2b7f8042e7416dbee800b5e8f5606b
FigureS3 from AsiDNA Is a Radiosensitizer with no Added Toxicity in Medulloblastoma Pediatric Models
Autor:
Marie Dutreix, Célio Pouponnot, François D. Boussin, Joel Mispelter, Mihaela Lupu, Sophie Heinrich, Magalie Larcher, Alberto Gatto, Chloe Foray, Sofia Ferreira
Effect of the combination of treatments in preclinical high-risk HDMB03 models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0545bd0508683a13750c883231be19da
https://doi.org/10.1158/1078-0432.22477776
https://doi.org/10.1158/1078-0432.22477776
Autor:
Marie Dutreix, Célio Pouponnot, François D. Boussin, Joel Mispelter, Mihaela Lupu, Sophie Heinrich, Magalie Larcher, Alberto Gatto, Chloe Foray, Sofia Ferreira
Legends for supplementary data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d79c3526e1c9de55d91a003816598a
https://doi.org/10.1158/1078-0432.22477770.v1
https://doi.org/10.1158/1078-0432.22477770.v1
Autor:
Marie Dutreix, Célio Pouponnot, François D. Boussin, Joel Mispelter, Mihaela Lupu, Sophie Heinrich, Magalie Larcher, Alberto Gatto, Chloe Foray, Sofia Ferreira
Purpose:Medulloblastoma is an important cause of mortality and morbidity in pediatric oncology. Here, we investigated whether the DNA repair inhibitor, AsiDNA, could help address a significant unmet clinical need in medulloblastoma care, by improving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9da6f13b4476dea6cfe675e8466d02
https://doi.org/10.1158/1078-0432.c.6529755.v1
https://doi.org/10.1158/1078-0432.c.6529755.v1
Autor:
Marie Dutreix, Célio Pouponnot, François D. Boussin, Joel Mispelter, Mihaela Lupu, Sophie Heinrich, Magalie Larcher, Alberto Gatto, Chloe Foray, Sofia Ferreira
Supplementary Table S2 - Significance and variation given by radiation, AsiDNA or interaction (AsiDNA with radiation) calculated by two-way ANOVA test.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3821e2aa944bca283ea8e0f54b50a37b
https://doi.org/10.1158/1078-0432.22477761
https://doi.org/10.1158/1078-0432.22477761