Zobrazeno 1 - 10
of 13
pro vyhledávání: '"François D'Anjou"'
Autor:
Frédéric Couture, Christine Levesque, Véronique Dumulon-Perreault, Samia Ait-Mohand, François D’Anjou, Robert Day, Brigitte Guérin
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 8, Pp 634-643 (2014)
The potential of PACE4 as a pharmacological target in prostate cancer has been demonstrated as this proprotein convertase is strongly overexpressed in human prostate cancer tissues and its inhibition, using molecular or pharmacological approaches, re
Externí odkaz:
https://doaj.org/article/4385aada31f04e14a1434a0ae825e80e
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 11, Pp 1032-1042 (2012)
Better understanding of the distinct and redundant functions of the proprotein convertase (PC) enzyme family within pathophysiological states has a great importance for potential therapeutic strategies. In this study, we investigated the functional r
Externí odkaz:
https://doaj.org/article/3fe40c5d3fc1461a94c0fa671e5cbfd9
Autor:
Samia Ait-Mohand, Veronique Dumulon-Perreault, Brigitte Guérin, Robert Day, François D'Anjou, Christine Levesque, Frédéric Couture
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 8, Pp 634-643 (2014)
The potential of PACE4 as a pharmacological target in prostate cancer has been demonstrated as this proprotein convertase is strongly overexpressed in human prostate cancer tissues and its inhibition, using molecular or pharmacological approaches, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1be381f2ab6870eebe353fd42abd9a8
http://www.sciencedirect.com/science/article/pii/S1476558614001043
http://www.sciencedirect.com/science/article/pii/S1476558614001043
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 11, Pp 1032-1042 (2012)
Better understanding of the distinct and redundant functions of the proprotein convertase (PC) enzyme family within pathophysiological states has a great importance for potential therapeutic strategies. In this study, we investigated the functional r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786885b032d30f683676fc7bc04846fe
http://www.sciencedirect.com/science/article/pii/S1476558612801151
http://www.sciencedirect.com/science/article/pii/S1476558612801151
Autor:
Eric Leblanc, Robert Day, Isabelle Farre, Rémi Longuespée, Maxence Wisztorski, Isabelle Fournier, François D'Anjou, Denis Vinatier, Charlotte Boyon, Michel Salzet, Annie Desmons, Kévin Ly
Publikováno v:
Cancer and Metastasis Reviews. 31:713-732
Ovarian cancer (OVC) is the fourth leading cause of cancer mortality among women in Europe and the United States. Its early detection is difficult due to the lack of specificity of clinical symptoms. Unfortunately, late diagnosis is a major contribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020223e23bf3b36352ca955e5bb13e6e
https://doi.org/10.1007/s10555-012-9383-7
https://doi.org/10.1007/s10555-012-9383-7
Publikováno v:
Biomolecular Concepts, Vol 2, Iss 5, Pp 421-438 (2011)
There is increasing interest in the therapeutic targeting of proteases for the treatment of important diseases. Additionally new protein-based therapeutic strategies have the potential to widen the available treatments against these pathologies. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a876f767d43b0043086ca6c83922d3
https://doi.org/10.1515/bmc.2011.034
https://doi.org/10.1515/bmc.2011.034
Autor:
François D'Anjou, Jean-Pierre Perreault, Michel Salzet, Nadia Ben Larbi, Isabelle Fournier, Lucien Junior Bergeron, Robert Day
Publikováno v:
Journal of Biological Chemistry. 279:14232-14239
Endoproteolytic processing is carried out by subtilase-like pro-protein convertases in mammalian cells. In order to understand the distinct roles of a member of this family (SPC2), gene silencing in cultured cells is an ideal approach. Previous studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13c7c693a8b05798a09482697fb68c7
https://doi.org/10.1074/jbc.m310632200
https://doi.org/10.1074/jbc.m310632200
Autor:
Anna Kwiatkowska, Robert Day, Sophie Beauchemin, Yves L. Dory, Frédéric Couture, Frédérik Dufour, Hugo Gagnon, Rolland Vaillancourt, François Malouin, Adamy Roberge Desbiens, Christine Levesque, Roxane Desjardins, François D'Anjou, Sylvain Bernard
Publikováno v:
Journal of medicinal chemistry. 57(1)
Proprotein convertases (PCs) are crucial in the processing and entry of viral or bacterial protein precursors and confer increased infectivity of pathogens bearing a PC activation site, which results in increased symptom severity and lethality. Previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8fd0afe96c599d1e130df9ba7183621
https://pubmed.ncbi.nlm.nih.gov/24359257
https://pubmed.ncbi.nlm.nih.gov/24359257
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1103
Gene silencing strategies targeting mRNA are suitable methods to validate the functions of specific genes. In this chapter, we sought to compare two knockdown strategies for the study of proprotein convertases and proliferation in prostate cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8c2504667fc18ffb0922b6b3e7df64c
https://pubmed.ncbi.nlm.nih.gov/24318887
https://pubmed.ncbi.nlm.nih.gov/24318887
Publikováno v:
Methods in Molecular Biology ISBN: 9781627037297
Gene silencing strategies targeting mRNA are suitable methods to validate the functions of specific genes. In this chapter, we sought to compare two knockdown strategies for the study of proprotein convertases and proliferation in prostate cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::712eb6085c2f956499d86cbbc73f8380
https://doi.org/10.1007/978-1-62703-730-3_6
https://doi.org/10.1007/978-1-62703-730-3_6
