Zobrazeno 1 - 10
of 74
pro vyhledávání: '"François Cossais"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 163, Iss , Pp 114814- (2023)
Neuroinflammation is both cause and effect of many neurodegenerative disorders. Activation of astrocytes and microglia leads to the release of cytokines and reactive oxygen species followed by blood-brain barrier leakage and neurotoxicity. Transient
Externí odkaz:
https://doaj.org/article/4744b2dbc0ab4d06a2ba825a07b1a0fc
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2078 (2024)
Brain diseases are oftentimes life-threatening and difficult to treat. The local administration of drug substances using brain implants can increase on-site concentrations and decrease systemic side effects. However, the biocompatibility of potential
Externí odkaz:
https://doaj.org/article/26c05867cc8246e4b35065d854a4d313
Autor:
Luise Schlotterose, Mariya S. Pravdivtseva, Frowin Ellermann, Olav Jansen, Jan-Bernd Hövener, Frank D. Sönnichsen, François Cossais, Ralph Lucius, Kirsten Hattermann
Publikováno v:
Antioxidants, Vol 12, Iss 6, p 1248 (2023)
The recognition of the role of microglia cells in neurodegenerative diseases has steadily increased over the past few years. There is growing evidence that the uncontrolled and persisting activation of microglial cells is involved in the progression
Externí odkaz:
https://doaj.org/article/64862e6961b145998bdccadd88d4e952
Autor:
Helena U. Zacharias, Christoph Kaleta, François Cossais, Eva Schaeffer, Henry Berndt, Lena Best, Thomas Dost, Svea Glüsing, Mathieu Groussin, Mathilde Poyet, Sebastian Heinzel, Corinna Bang, Leonard Siebert, Tobias Demetrowitsch, Frank Leypoldt, Rainer Adelung, Thorsten Bartsch, Anja Bosy-Westphal, Karin Schwarz, Daniela Berg
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1222 (2022)
Neurodegenerative diseases such as Parkinson’s (PD) and Alzheimer’s disease (AD), the prevalence of which is rapidly rising due to an aging world population and westernization of lifestyles, are expected to put a strong socioeconomic burden on he
Externí odkaz:
https://doaj.org/article/7d8ee761bc3b429883ffe88269a4d956
Publikováno v:
Cells, Vol 11, Iss 19, p 3107 (2022)
Sodium-glucose cotransporter 2 (SGLT2) inhibitors, including empagliflozin, are routinely used as antidiabetic drugs. Recent studies indicate that beside its beneficial effects on blood glucose level, empagliflozin may also exert vascular anti-inflam
Externí odkaz:
https://doaj.org/article/7fe37000d3b246829b6494095d2889bf
Autor:
Yuk Lung Wong, Ingmar Lautenschläger, Lars Hummitzsch, Karina Zitta, François Cossais, Thilo Wedel, Rene Rusch, Rouven Berndt, Matthias Gruenewald, Norbert Weiler, Markus Steinfath, Martin Albrecht
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256957 (2021)
BackgroundIntestinal ischemia/reperfusion (I/R)-injury often results in sepsis and organ failure and is of major importance in the clinic. A potential strategy to reduce I/R-injury is the application of ischemic preconditioning (IPC) during which rep
Externí odkaz:
https://doaj.org/article/8fe7b12984554b22ac6ef67557b5f3d9
Autor:
Martina Barrenschee, François Cossais, Martina Böttner, Jan-Hendrik Egberts, Thomas Becker, Thilo Wedel
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Neuregulin 1 (NRG1) regulates the expression of the nicotinic acetylcholine receptor (nAChR) and is suggested to promote the survival and maintenance of the enteric nervous system (ENS), since deficiency of its corresponding receptor complex ErbB2/Er
Externí odkaz:
https://doaj.org/article/7e75bd291d43452095db613f1e8b382b
Autor:
Hattermann, Luise Schlotterose, Mariya S. Pravdivtseva, Frowin Ellermann, Olav Jansen, Jan-Bernd Hövener, Frank D. Sönnichsen, François Cossais, Ralph Lucius, Kirsten
Publikováno v:
Antioxidants; Volume 12; Issue 6; Pages: 1248
The recognition of the role of microglia cells in neurodegenerative diseases has steadily increased over the past few years. There is growing evidence that the uncontrolled and persisting activation of microglial cells is involved in the progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::3a2b6e8dda1cd0c817b503a841f72144
Autor:
Björn-Ole Bast, Uta Rickert, Janna Schneppenheim, François Cossais, Henrik Wilms, Philipp Arnold, Ralph Lucius
Publikováno v:
Heliyon, Vol 4, Iss 10, Pp e00826- (2018)
Over the last years, studies on microglia cell function in chronic neuro-inflammation and neuronal necrosis pointed towards an eminent role of these cells in Multiple Sclerosis, Parkinson's and Alzheimer's Disease. It was found, that microglia cell a
Externí odkaz:
https://doaj.org/article/d019fa08174c43dbb77cea036b3667a9
Autor:
Sébastien Paillusson, Roberto De Giorgio, Adrien de Guilhem de Lataillade, François Cossais, Michel Neunlist, Laurène Leclair-Visonneau, Pascal Derkinderen
Publikováno v:
Journal of Neural Transmission. 129:1095-1103
Alpha-synuclein deposits, the pathological hallmarks of Parkinson's disease, are consistently found in the gastrointestinal tract of parkinsonian subjects. These observations have raised the potential that endoscopically obtainable mucosal biopsies c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ddb5c8717a87fee9d4ece553da323c1
https://doi.org/10.1007/s00702-021-02445-6
https://doi.org/10.1007/s00702-021-02445-6