Zobrazeno 1 - 7
of 7
pro vyhledávání: '"François Cesbron"'
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83660 (2013)
We show that firefly luciferase is a stable protein when expressed at 25 °C in Neurospora, which limits its use as transcription reporter. We created a short-lived luciferase by fusing a PEST signal to its C-terminus (LUC-PEST) and applied the LUC-P
Externí odkaz:
https://doaj.org/article/e74ed0b819264b5ba247a23c9639f497
Publikováno v:
PLoS Biology, Vol 9, Iss 2, p e1000595 (2011)
The mammalian circadian clock uses interlocked negative feedback loops in which the heterodimeric basic helix-loop-helix transcription factor BMAL1/CLOCK is a master regulator. While there is prominent control of liver functions by the circadian cloc
Externí odkaz:
https://doaj.org/article/c2ee8c98031d4142ad02218a776e5d72
Publikováno v:
Cell systems. 6(4)
Gene regulation is a complex non-equilibrium process. Here, we show that quantitating the temporal regulation of key gene states (transcriptionally inactive, active, and refractory) provides a parsimonious framework for analyzing gene regulation. Our
Publikováno v:
BMC Biology
Background Circadian clocks control rhythmic expression of a large number of genes in coordination with the 24 hour day-night cycle. The mechanisms generating circadian rhythms, their amplitude and circadian phase are dependent on a transcriptional n
Publikováno v:
Nature communications. 6
Genes are often transcribed in random bursts followed by long periods of inactivity. Here we employ the light-activatable white collar complex (WCC) of Neurospora to study the transcriptional bursting with a population approach. Activation of WCC by
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e83660 (2013)
PLoS ONE, Vol 8, Iss 12, p e83660 (2013)
We show that firefly luciferase is a stable protein when expressed at 25 °C in Neurospora, which limits its use as transcription reporter. We created a short-lived luciferase by fusing a PEST signal to its C-terminus (LUC-PEST) and applied the LUC-P
Publikováno v:
PLoS Biology
PLoS biology
PLoS Biology, Vol 9, Iss 2, p e1000595 (2011)
PLoS biology
PLoS Biology, Vol 9, Iss 2, p e1000595 (2011)
Temporal mapping during a circadian day of binding sites for the BMAL1 transcription factor in mouse liver reveals genome-wide daily rhythms in DNA binding and uncovers output functions that are controlled by the circadian oscillator.
The mammal
The mammal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3eebb838c855af0b622e489181a37a
https://infoscience.epfl.ch/record/164134
https://infoscience.epfl.ch/record/164134