Zobrazeno 1 - 10
of 31
pro vyhledávání: '"François Bertaux"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Optimizing the production of recombinant proteins is a problem of major industrial and pharmaceutical importance. Secretion of the protein by the host cell considerably simplifies downstream purification processes. However, for many proteins
Externí odkaz:
https://doaj.org/article/9101ca7eba1f4167ba2f87cba492c34a
Autor:
François Bertaux, Sebastián Sosa-Carrillo, Viktoriia Gross, Achille Fraisse, Chetan Aditya, Mariela Furstenheim, Gregory Batt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Small-scale bioreactors are increasingly used in quantitative biology. Here, the authors report ReacSight, a software solution to connect reactor arrays with sensitive measurement devices using low-cost pipetting robots and provide applications lever
Externí odkaz:
https://doaj.org/article/5b144b6eba054bb8a1359d205403f63a
Autor:
Zachary R. Fox, Steven Fletcher, Achille Fraisse, Chetan Aditya, Sebastián Sosa-Carrillo, Julienne Petit, Sébastien Gilles, François Bertaux, Jakob Ruess, Gregory Batt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
In microscopy, applications in which reactiveness is needed are multifarious. Here the authors report MicroMator, a Python software package for reactive experiments, which they use for applications requiring real-time tracking and light-targeting at
Externí odkaz:
https://doaj.org/article/3bc80086b5de48f6bcbae6396a5613e1
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Artificial microbial consortia use division-of-labour to optimize production. Here the authors develop an optogenetic differentiation system in yeast to generate consortia from a single strain with tunable composition.
Externí odkaz:
https://doaj.org/article/540ce59a5ca2421cacf952d00a3e20f4
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 9, p e1008245 (2020)
Universal observations in Biology are sometimes described as "laws". In E. coli, experimental studies performed over the past six decades have revealed major growth laws relating ribosomal mass fraction and cell size to the growth rate. Because they
Externí odkaz:
https://doaj.org/article/ce12280154cb4f10a7719f929fbb0aed
Publikováno v:
Royal Society Open Science, Vol 5, Iss 3 (2018)
The cell division rate, size and gene expression programmes change in response to external conditions. These global changes impact on average concentrations of biomolecule and their variability or noise. Gene expression is inherently stochastic, and
Externí odkaz:
https://doaj.org/article/8b5fefe34f624235a781dcbcc9020ed3
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 10, p e1003893 (2014)
Isogenic cells sensing identical external signals can take markedly different decisions. Such decisions often correlate with pre-existing cell-to-cell differences in protein levels. When not neglected in signal transduction models, these differences
Externí odkaz:
https://doaj.org/article/dff2d1d477814014a530c09e09f25eab
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 5, p e1003056 (2013)
Extrinsic apoptosis is a programmed cell death triggered by external ligands, such as the TNF-related apoptosis inducing ligand (TRAIL). Depending on the cell line, the specific molecular mechanisms leading to cell death may significantly differ. Pre
Externí odkaz:
https://doaj.org/article/9ca5abdc7bb740888469515771894b01
Publikováno v:
Nature Communications
Nature Communications, 2023, 14 (1), pp.3028. ⟨10.1038/s41467-023-38807-9⟩
Nature Communications, 2023, 14 (1), pp.3028. ⟨10.1038/s41467-023-38807-9⟩
The production of recombinant proteins is a problem of major industrial and pharmaceutical importance. Secretion of the protein by the host cell considerably simplifies downstream purification processes. However, it is also the limiting production st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38bca4efe33222a67dd3c00aaefc9dfb
https://doi.org/10.1101/2022.11.02.514931
https://doi.org/10.1101/2022.11.02.514931
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (11), pp.e2114438119. ⟨10.1073/pnas.211443811⟩
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (11), pp.e2114438119. ⟨10.1073/pnas.211443811⟩
Posté sur BioRxiv le 4 août 2021; International audience; Mathematical modeling has become a major tool to guide the characterization and synthetic construction of cellular processes. However, models typically lose their capacity to explain or pred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211e96a36e8aab217e08f5a99464bf34
https://doi.org/10.1073/pnas.2114438119
https://doi.org/10.1073/pnas.2114438119