Zobrazeno 1 - 10
of 41
pro vyhledávání: '"François B. Michel"'
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 198:745-756
Asthma and allergic diseases generally start early in life and persist throughout life but, for reasons we do not yet understand, they sometimes appear later Prevention, early diagnosis and treatment of these major chronic respiratory diseases is a r
Publikováno v:
Clinical Reviews in Allergy and Immunology. 14:247-252
Most of the current trends in the management of asthma are devoted to environmental and pharmacological interventions. The major drawbacks of the so-called controversial therapies remain the lack of convincing proof of efficacy and safety. They are c
Autor:
Giovanni Bonsignore, Pascal Chanez, Antonio M. Vignola, François-B. Michel, Jean Bousquet, Alison M. Campbell
Publikováno v:
International Archives of Allergy and Immunology. 107:211-214
Asthma is a chronic inflammatory disease of the airways invariably associated with healing. Remodelling of the airways can be demonstrated by the activation of airways macrophages, the release of growth factors and fibrogenic cytokines, the activatio
Autor:
Pascal Chanez, Antonio M. Vignola, Philippe Godard, Alison M. Campbell, Jean Bousquet, François B. Michel
Publikováno v:
Clinical Immunotherapeutics. 2:468-477
The bronchial epithelium has metabolic and immunological properties that involve the release of a range of mediators and interaction with other cell types within the lung. It also acts as a dynamic barrier, regulating the penetration and the traffic
Autor:
Lawrence B. Schwartz, Bernard Guerrier, Pascal Demoly, François B. Michel, I. Enander, Michel Mondain, Nadine Lequeuxc, Jean Bousquet, Alison M. Campbell, Louis Crampette
Publikováno v:
Journal of Allergy and Clinical Immunology. 94:95-108
Background and aim: Pathologic examination of the sinus mucosa and titration of inflammatory mediators in the sinus fluid were carried out to characterize inflammation in chronic sinusitis and determine whether patients with chronic allergic rhinitis
Autor:
Jean Bousquet, François-B. Michel
Publikováno v:
Journal of Allergy and Clinical Immunology. 94:1-11
Autor:
H. Dhivert, A. Chicoye, Jean Bousquet, A. Richard, François B. Michel, John E. Ware, J. Knani
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 149:371-375
Asthma is a chronic disease in which social life is altered. The importance of restrictions on social life may be greater in severe asthma or when symptoms are not adequately controlled. General scales of quality-of-life (QOL) may be used to detect t
Autor:
Pascal Chanez, Philippe Vago, Pascal Demoly, Jean Bousquet, Jean Paul Bureau, Laure Cornillac, Philippe Godard, François B. Michel
Publikováno v:
Journal of Allergy and Clinical Immunology. 92:869-877
Background: Macrophages are involved in asthma, but their pulmonary turnover is unknown. We compared the ability of bronchoalveolar lavage (BAL) and bronchial macrophages to proliferate in normal subjects and patients with asthma. Methods: BAL cells
Autor:
Antonio M. Vignola, Pascale Paul-Lacoste, Pascal Chanez, Philippe Godard, Alison M. Campbell, Jean Bousquet, François-B. Michel
Publikováno v:
American Review of Respiratory Disease. 148:689-694
HLA-DR and ICAM-I molecules play an important role in cellular interactions, and their expression can be induced by inflammatory stimuli. We evaluated the spontaneous expression of HLA-DR and ICAM-1 on epithelial cells obtained by bronchial brushing
Autor:
André Crastes de Paulet, Isabelle Vachier, Philipe Godard, Pascal Chanez, François B. Michel, Christian Le Doucen, M. Damon
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
Besides eosinophils, inflammatory processes in asthma are characterized by an infiltration of inflammatory cells, including mononuclear phagocytes, such as alveolar macrophages (AM) and blood monocytes, in the airways. Monocyte activation has been ob