Zobrazeno 1 - 10
of 50
pro vyhledávání: '"François Authier"'
Publikováno v:
Arthritis & Rheumatology. 73:1566-1567
We thank Drs Pinal-Fernandez and Mammen for their constructive comments on our article (1). We also thank them about their remark related to the correlations between muscle levels of ISG15 and muscle involvement. We fully agree that an accurate class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f50316909c064eb132c9e35b75fba42
https://doi.org/10.1002/art.41706
https://doi.org/10.1002/art.41706
Publikováno v:
Journal of visualized experiments : JoVE. (154)
The necrosis of muscle fibres (myonecrosis) plays a central role in the pathogenesis of several muscle conditions, including muscular dystrophies. Therapeutic options addressing the causes of muscular dystrophy pathogenesis are expected to alleviate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55263d908948b6894884a19ed53f7569
https://pubmed.ncbi.nlm.nih.gov/31868171
https://pubmed.ncbi.nlm.nih.gov/31868171
Autor:
Séverine Lorin, François Authier, Mojgan Djavaheri-Mergny, Jean-Pierre Frénoy, Bernard Desbuquois
Publikováno v:
Cellular Microbiology. 18:1800-1814
Cytotoxicity of many plant and bacterial toxins requires their endocytosis and retrograde transport from endosomes to the endoplasmic reticulum. Using cell fractionation and immunoblotting procedures, we have assessed the fate and action of the plant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e9470b17cf614bde59996f13d73061c
https://doi.org/10.1111/cmi.12621
https://doi.org/10.1111/cmi.12621
Autor:
Bernard Desbuquois, François Authier
Publikováno v:
Biologie Aujourd'hui. 208:137-150
The insulin receptor and insulin signaling proteins downstream the receptor reside in different subcellular compartments and undergo redistribution within the cell upon insulin activation. Endocytosis of the insulin-receptor complex, by mediating lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f77ecad3672c7ac209b074200b229d78
https://doi.org/10.1051/jbio/2014016
https://doi.org/10.1051/jbio/2014016
Autor:
Mojgan Djavaheri-Mergny, François Authier, Paulette Decottignies, Tatiana El Hage, Séverine Lorin
Publikováno v:
FEBS Journal. 277:3735-3749
To assess Pseudomonas exotoxin A (ETA) compartmentalization, processing and cytotoxicity in vivo, we have studied the fate of internalized ETA with the use of the in vivo rodent liver model following toxin administration, cell-free hepatic endosomes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12471b2dc3809b2f2a1039d287c982c2
https://doi.org/10.1111/j.1742-4658.2010.07775.x
https://doi.org/10.1111/j.1742-4658.2010.07775.x
Publikováno v:
FEBS Journal. 275:4363-4377
The molecular adaptor Grb14 binds in vitro to the activated insulin receptor (IR) and inhibits IR signaling. In this study, we have used rat liver subcellular fractionation to analyze in vivo insulin effects on Grb14 compartmentalization and IR phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c53baa9f5c2822bb6a5991e3431539b
https://doi.org/10.1111/j.1742-4658.2008.06583.x
https://doi.org/10.1111/j.1742-4658.2008.06583.x
Publikováno v:
FEBS Journal. 274:2614-2629
Using the in situ liver model system, we have recently shown that, after cholera toxin binding to hepatic cells, cholera toxin accumulates in a low-density endosomal compartment, and then undergoes endosomal proteolysis by the aspartic acid protease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::146b49a39555d1bf6a92aaed424149a8
https://doi.org/10.1111/j.1742-4658.2007.05797.x
https://doi.org/10.1111/j.1742-4658.2007.05797.x
Autor:
François, Authier, Mojgan, Djavaheri-Mergny, Séverine, Lorin, Jean-Pierre, Frénoy, Bernard, Desbuquois
Publikováno v:
Cellular microbiology. 18(12)
Cytotoxicity of many plant and bacterial toxins requires their endocytosis and retrograde transport from endosomes to the endoplasmic reticulum. Using cell fractionation and immunoblotting procedures, we have assessed the fate and action of the plant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69fb33d2527d122b1a0ee90b76956e9e
https://pubmed.ncbi.nlm.nih.gov/27235692
https://pubmed.ncbi.nlm.nih.gov/27235692
Publikováno v:
FEBS Letters. 579:4309-4316
IGF-I is degraded within the endosomal apparatus as a consequence of receptor-mediated endocytosis. However, the nature of the responsible protease and the position of the cleavage sites in the IGF-I molecule remain undefined. In vitro proteolysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f48bba8dd61cc023ad1a5d4ed81cac
https://doi.org/10.1016/j.febslet.2005.06.066
https://doi.org/10.1016/j.febslet.2005.06.066
Endosomal Proteolysis of Internalized Insulin at the C-terminal Region of the B Chain by Cathepsin D
Publikováno v:
Journal of Biological Chemistry. 277:9437-9446
The endosomal compartment of hepatic parenchymal cells contains an acidic endopeptidase, endosomal acidic insulinase, which hydrolyzes internalized insulin and generates the major primary end product A(1--21)-B(1--24) insulin resulting from a major c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0df1230c8b4511eb4443bae00e7da92
https://doi.org/10.1074/jbc.m110188200
https://doi.org/10.1074/jbc.m110188200