New susceptibility loci associated with kidney disease in type 1 diabetes.

Autor: Niina Sandholm, Rany M Salem, Amy Jayne McKnight, Eoin P Brennan, Carol Forsblom, Tamara Isakova, Gareth J McKay, Winfred W Williams, Denise M Sadlier, Ville-Petteri Mäkinen, Elizabeth J Swan, Cameron Palmer, Andrew P Boright, Emma Ahlqvist, Harshal A Deshmukh, Benjamin J Keller, Huateng Huang, Aila J Ahola, Emma Fagerholm, Daniel Gordin, Valma Harjutsalo, Bing He, Outi Heikkilä, Kustaa Hietala, Janne Kytö, Päivi Lahermo, Markku Lehto, Raija Lithovius, Anne-May Osterholm, Maija Parkkonen, Janne Pitkäniemi, Milla Rosengård-Bärlund, Markku Saraheimo, Cinzia Sarti, Jenny Söderlund, Aino Soro-Paavonen, Anna Syreeni, Lena M Thorn, Heikki Tikkanen, Nina Tolonen, Karl Tryggvason, Jaakko Tuomilehto, Johan Wadén, Geoffrey V Gill, Sarah Prior, Candace Guiducci, Daniel B Mirel, Andrew Taylor, S Mohsen Hosseini, DCCT/EDIC Research Group, Hans-Henrik Parving, Peter Rossing, Lise Tarnow, Claes Ladenvall, François Alhenc-Gelas, Pierre Lefebvre, Vincent Rigalleau, Ronan Roussel, David-Alexandre Tregouet, Anna Maestroni, Silvia Maestroni, Henrik Falhammar, Tianwei Gu, Anna Möllsten, Danut Cimponeriu, Mihai Ioana, Maria Mota, Eugen Mota, Cristian Serafinceanu, Monica Stavarachi, Robert L Hanson, Robert G Nelson, Matthias Kretzler, Helen M Colhoun, Nicolae Mircea Panduru, Harvest F Gu, Kerstin Brismar, Gianpaolo Zerbini, Samy Hadjadj, Michel Marre, Leif Groop, Maria Lajer, Shelley B Bull, Daryl Waggott, Andrew D Paterson, David A Savage, Stephen C Bain, Finian Martin, Joel N Hirschhorn, Catherine Godson, Jose C Florez, Per-Henrik Groop, Alexander P Maxwell

Publikováno v: PLoS Genetics, Vol 8, Iss 9, p e1002921 (2012)

Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or kidney transplantation. In addition to the decrease in the quality

Externí odkaz: https://doaj.org/article/818e5a61debb4667aafbe14358bd9b2a

Ervin G. Erdös, MD, (October 16, 1922–November 17, 2019)

Autor: François Alhenc-Gelas, William B. Campbell, Randal A. Skidgel

Publikováno v: Hypertension. 75:1360-1362

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c59ad153481444555279a65c1337f79
https://doi.org/10.1161/hypertensionaha.120.14394

ACE I/D Polymorphism, Plasma ACE Levels, and Long-term Kidney Outcomes or All-Cause Death in Patients With Type 1 Diabetes

Autor: Séverine Dubois, André Scheen, Charlyne Carpentier, Samy Hadjadj, François Alhenc-Gelas, Pierre Gourdy, Ronan Roussel, Michel Marre, Yawa Abouleka, Jean-François Gautier, Gilberto Velho, Kamel Mohammedi

Publikováno v: Diabetes Care

OBJECTIVE The deletion (D) allele of the ACE insertion/deletion (I/D) polymorphism is a risk factor for diabetic kidney disease. We assessed its contribution to long-term kidney outcomes and all-cause death in patients with long-standing type 1 diabe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1bcb60544d11ed14e5e0b4e53c4644
https://europepmc.org/articles/PMC8247517/

Blockade of SARS-CoV-2 infection by recombinant soluble ACE2

Autor: Tilman B. Drüeke, François Alhenc-Gelas

Publikováno v: Kidney International

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83517673e10fff3f1d4ff4d2b90f5a4f

Is Plasma Renin Activity Genetically Determined and How Much Does It Matter for Treating Hypertension?

Autor: François Alhenc-Gelas, Joël Ménard

Publikováno v: Circulation: Genomic and Precision Medicine. 11

See Article by McDonough et al Abundance of a protein in tissues or fluids is probably a quantitative genetic trait in most or even all cases. This can, however, be difficult recognizing and quantifying, depending on whether cellular or secreted prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eae4b5cba2cac53b129616c8de42f602
https://doi.org/10.1161/circgen.118.002139