Three Decades of Ultrasound Contrast Agents: A Review of the Past, Present and Future Improvements

Autor: Peter Frinking, François Tranquart, Tim Segers, Ying Luan

Publikováno v: Ultrasound in Medicine & Biology. 46:892-908

Initial reports from the 1960s describing the observations of ultrasound contrast enhancement by tiny gaseous bubbles during echocardiographic examinations prompted the development of the first ultrasound contrast agent in the 1980s. Current commerci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ea47c3733b307ad9fd73c19a37f6f0
https://doi.org/10.1016/j.ultrasmedbio.2019.12.008

Intranasal Vaccination With Salmonella -Derived Serodominant Secreted Effector Protein B Associated With Gas-Filled Microbubbles Partially Protects Against Gut Infection in Mice

Autor: François Tranquart, Anne Lassus, Blaise Corthésy, Gilles Bioley, Fiona Pigny, Jacques Terrettaz

Publikováno v: Journal of Infectious Diseases

Salmonella infection is an increasingly important public health problem owing to the emergence of multidrug resistance and the lack of broadly efficient vaccines. Novel strategies of vaccination are required to induce protective immune responses at m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bf441497fc49ea88bf635be5132e4f

Microbubbles combined with ultrasound therapy in ischemic stroke: A systematic review of in-vivo preclinical studies

Autor: Jean-Marc Hyvelin, Ayache Bouakaz, Jean-Michel Escoffre, François Tranquart, Laurent Auboire, Charles A. Sennoga, Frédéric Ossant

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2018, 13 (2), pp.e0191788. ⟨10.1371/journal.pone.0191788⟩
PLoS ONE, Vol 13, Iss 2, p e0191788 (2018)

Background Microbubbles (MBs) combined with ultrasound sonothrombolysis (STL) appears to be an alternative therapeutic strategy for acute ischemic stroke (IS), but clinical results remain controversial. Objective The aim of this systematic review is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3abb38dc430538b90168f862484255
https://hal.archives-ouvertes.fr/hal-01761337

First-in-human ultrasound molecular imaging with a VEGFR2-specific ultrasound molecular contrast agent (BR55) in prostate cancer a safety and feasibility pilot study

Autor: Jean J.M.C.H. de la Rosette, Theo M. de Reijke, Hessel Wijkstra, Christophe K. Mannaerts, François Tranquart, M. Pilar Laguna, Marc J. van de Vijver, Martijn Smeenge, Sibylle Pochon

Publikováno v: Investigative Radiology, 52(7), 419-427. Lippincott Williams and Wilkins Ltd.
Investigative radiology, 52(7), 419-427. Lippincott Williams and Wilkins

Objective: BR55, a vascular endothelial growth factor receptor 2 (VEGFR2)–specific ultrasound molecular contrast agent (MCA), has shown promising results in multiple preclinical models regarding cancer imaging. In this first-in-human, phase 0, expl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6a0a40b25794549858a95de7f6f1e2
https://research.tue.nl/nl/publications/7abab343-130e-4587-a60f-7ee3bced64a3

Ultrasound Contrast Agents For Ultrasound Molecular Imaging

Autor: S. Pochon, A. D. Nunn, T. Bettinger, P. Frinking, M. Arditi, J. M. Hyvelin, Isabelle Tardy, François Tranquart

Publikováno v: Zeitschrift für Gastroenterologie. 52:1268-1276

Ultrasound is a real-time imaging technique which is widely used in many clinical applications for its capacity to provide anatomic information with high spatial and temporal resolution. The advent of ultrasound contrast agents in combination with co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778659366425f62ccab7ad4b9c697e4a
https://doi.org/10.1055/s-0034-1384999