Zobrazeno 1 - 10
of 85
pro vyhledávání: '"François, Kuonen"'
Publikováno v:
Acta Dermato-Venereologica, Vol 104 (2024)
Martorell hypertensive ulcer (MHU) represents a painful, difficult-to-handle condition associated with peri-pheral, subcutaneous arteriolosclerosis caused by chronic hypertensive disease. Betablockers are effective for and widely used to treat hypert
Externí odkaz:
https://doaj.org/article/0362a97b622848b69bb082dd1a5002f8
Autor:
Yun-Tsan Chang, Pacôme Prompsy, Susanne Kimeswenger, Yi-Chien Tsai, Desislava Ignatova, Olesya Pavlova, Christoph Iselin, Lars E. French, Mitchell P. Levesque, François Kuonen, Malgorzata Bobrowicz, Patrick M. Brunner, Steve Pascolo, Wolfram Hoetzenecker, Emmanuella Guenova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Cancer-associated immune dysfunction is a major challenge for effective therapies. The emergence of antibodies targeting tumor cell-surface antigens led to advancements in the treatment of hematopoietic malignancies, particularly blood cance
Externí odkaz:
https://doaj.org/article/1a3bf0a991644740869501ab71bb08ef
Autor:
Anissa Fries, Fanny Saidoune, François Kuonen, Isabelle Dupanloup, Nadine Fournier, Ana Cristina Guerra de Souza, Muzlifah Haniffa, Feiyang Ma, Johann E. Gudjonsson, Lennart Roesner, Yang Li, Thomas Werfel, Curdin Conrad, Raphael Gottardo, Robert L. Modlin, Jeremy Di Domizio, Michel Gilliet
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Interleukin (IL)-26 is a TH17 cytokine with known antimicrobial and pro-inflammatory functions. However, the precise role of IL-26 in the context of pathogenic TH17 responses is unknown. Here we identify a population of blood TH17 intermedia
Externí odkaz:
https://doaj.org/article/9a6badc4e12148d591a4960524014626
Autor:
Nebiha Kechrid, MD, Luca Tonellotto, MD, Sandra Monnier, MD, Severin A. Rossi, MD, Franzisca Ulrich, MD, François Kuonen, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 27, Iss , Pp 41-45 (2022)
Externí odkaz:
https://doaj.org/article/7e98649681984ce680ffc6e73c6bf491
Autor:
Laura Yerly, Christine Pich-Bavastro, Jeremy Di Domizio, Tania Wyss, Stéphanie Tissot-Renaud, Michael Cangkrama, Michel Gilliet, Sabine Werner, François Kuonen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The role of reciprocal tumour-stroma interactions in tumour invasion remains poorly characterised. Here, single-cell and spatial transcriptomics identifies the cell populations and their transcriptional reprogramming contributing to the spatial organ
Externí odkaz:
https://doaj.org/article/ea3f55ef4f1f4bc89b960a13a7cc8b39
Autor:
Jasmin Bartl, Marco Zanini, Flavia Bernardi, Antoine Forget, Lena Blümel, Julie Talbot, Daniel Picard, Nan Qin, Gabriele Cancila, Qingsong Gao, Soumav Nath, Idriss Mahoungou Koumba, Marietta Wolter, François Kuonen, Maike Langini, Thomas Beez, Christopher Munoz, David Pauck, Viktoria Marquardt, Hua Yu, Judith Souphron, Mascha Korsch, Christina Mölders, Daniel Berger, Sarah Göbbels, Frauke-Dorothee Meyer, Björn Scheffler, Barak Rotblat, Sven Diederichs, Vijay Ramaswamy, Hiromishi Suzuki, Anthony Oro, Kai Stühler, Anja Stefanski, Ute Fischer, Gabriel Leprivier, Dieter Willbold, Gerhard Steger, Alexander Buell, Marcel Kool, Peter Lichter, Stefan M. Pfister, Paul A. Northcott, Michael D. Taylor, Arndt Borkhardt, Guido Reifenberger, Olivier Ayrault, Marc Remke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Long non-coding RNAs (lncRNAs) can contribute to cancers that are driven by Sonic hedgehog (SHH) signaling. Here the authors report that lncRNA HHIP-AS1 stabilises the mRNA of dynein complex 1, thereby, promoting the pro-mitotic effects of SHH-driven
Externí odkaz:
https://doaj.org/article/73686bb8743949ee8fd430a7515a3767
Autor:
François Kuonen, Nancy Yanzhe Li, Daniel Haensel, Tiffany Patel, Sadhana Gaddam, Laura Yerly, Kerri Rieger, Sumaira Aasi, Anthony E. Oro
Publikováno v:
Cell Reports, Vol 37, Iss 1, Pp 109774- (2021)
Summary: While squamous transdifferentiation within subpopulations of adenocarcinomas represents an important drug resistance problem, its underlying mechanism remains poorly understood. Here, using surface markers of resistant basal cell carcinomas
Externí odkaz:
https://doaj.org/article/9aa5bd39daa94ef991f899bb661af1b2
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The extracellular matrix (ECM) is a complex network composed of a multitude of different macromolecules. ECM components typically provide a supportive structure to the tissue and engender positional information and crosstalk with neighboring cells in
Externí odkaz:
https://doaj.org/article/704909dfc4764ee590c1d61ba18e1512
Autor:
Curzio Rüegg, René-Olivier Mirimanoff, Snezana Andrejevic-Blant, Reto Schwendener, Gian-Carlo Alghisi, Grégory Bieler, Eveline Faes-van't Hull, Thierry Rausch, Jean-Christophe Stehle, Girieca Lorusso, Chiara Secondini, Julien Laurent, François Kuonen
PDF file, 111KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85fa26b96885a2c48084c0f4d2ac9f6a
https://doi.org/10.1158/1078-0432.22442604
https://doi.org/10.1158/1078-0432.22442604
Autor:
Curzio Rüegg, René-Olivier Mirimanoff, Snezana Andrejevic-Blant, Reto Schwendener, Gian-Carlo Alghisi, Grégory Bieler, Eveline Faes-van't Hull, Thierry Rausch, Jean-Christophe Stehle, Girieca Lorusso, Chiara Secondini, Julien Laurent, François Kuonen
PDF file, 42KB, Effect of mammary gland pre-irradiation on primary tumor growth and liver metastases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060a8eb441047fb708bbf4045c7c43d4
https://doi.org/10.1158/1078-0432.22442628
https://doi.org/10.1158/1078-0432.22442628