Výsledky vyhledávání - "François, Davodeau"

Akademický článek

SPECT-CT Imaging of Dog Spontaneous Diffuse Large B-Cell Lymphoma Targeting CD22 for the Implementation of a Relevant Preclinical Model for Human

Autor: Floriane Etienne, Maxime Berthaud, Frédérique Nguyen, Karine Bernardeau, Catherine Maurel, Caroline Bodet-Milin, Maya Diab, Jérôme Abadie, Valérie Gouilleux-Gruart, Aurélien Vidal, Mickaël Bourgeois, Nicolas Chouin, Catherine Ibisch, François Davodeau

Publikováno v: Frontiers in Oncology, Vol 10 (2020)

Antibodies directed against CD22 have been used in radioimmunotherapy (RIT) clinical trials to treat patients with diffuse large B-cell lymphoma (DLBCL) with promising results. However, relevant preclinical models are needed to facilitate the evaluat

Externí odkaz: https://doaj.org/article/7e71b67d23e4426780eb2e53d47f0a08

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Akademický článek

Antitumor Immunity Induced after α Irradiation

Autor: Jean-Baptiste Gorin, Jérémie Ménager, Sébastien Gouard, Catherine Maurel, Yannick Guilloux, Alain Faivre-Chauvet, Alfred Morgenstern, Frank Bruchertseifer, Michel Chérel, François Davodeau, Joëlle Gaschet

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 4, Pp 319-328 (2014)

Radioimmunotherapy (RIT) is a therapeutic modality that allows delivering of ionizing radiation directly to targeted cancer cells. Conventional RIT uses β-emitting radioisotopes, but recently, a growing interest has emerged for the clinical developm

Externí odkaz: https://doaj.org/article/256472fb83534cd293b09b0b436d237a

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Akademický článek

Long-Term Toxicity of 213Bi-Labelled BSA in Mice.

Autor: Laëtitia Dorso, Edith Bigot-Corbel, Jérôme Abadie, Maya Diab, Sébastien Gouard, Frank Bruchertseifer, Alfred Morgenstern, Catherine Maurel, Michel Chérel, François Davodeau

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0151330 (2016)

Short-term toxicological evaluations of alpha-radioimmunotherapy have been reported in preclinical assays, particularly using bismuth-213 (213Bi). Toxicity is greatly influenced not only by the pharmacokinetics and binding specificity of the vector b

Externí odkaz: https://doaj.org/article/6b9082b483f14a40be2de1e420330e30

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Akademický článek

Combining α-Radioimmunotherapy and Adoptive T Cell Therapy to Potentiate Tumor Destruction.

Autor: Jérémie Ménager, Jean-Baptiste Gorin, Catherine Maurel, Lucile Drujont, Sébastien Gouard, Cédric Louvet, Michel Chérel, Alain Faivre-Chauvet, Alfred Morgenstern, Frank Bruchertseifer, François Davodeau, Joëlle Gaschet, Yannick Guilloux

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0130249 (2015)

Ionizing radiation induces direct and indirect killing of cancer cells and for long has been considered as immunosuppressive. However, this concept has evolved over the past few years with the demonstration that irradiation can increase tumor immunog

Externí odkaz: https://doaj.org/article/b3759baf927d447e88b80403dbb76309

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Radioimmunotherapy of Lymphomas

Autor: François Davodeau, Joëlle Gaschet, Clément Bailly, Mickaël Bourgeois, Alain Faivre-Chauvet, Michel Chérel, Nicolas Chouin, Caroline Bodet-Milin, François Guérard, Françoise Kraeber-Bodéré

Publikováno v: Nuclear Medicine Therapy
Nuclear Medicine Therapy, 2019, ⟨10.1007/978-3-030-17494-1_8⟩
Nuclear Medicine Therapy ISBN: 9783030174934

Lymphomas are a diverse range of hematologic tumors that arise from cells of the immune system. This chapter discusses recent available clinical data on the use of radioimmunotherapy (RIT) to treat this indication. RIT is a targeted therapy where rad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11b97a88430829a5e0f308355df88ba
https://www.hal.inserm.fr/inserm-02309716

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Production and characterization of monoclonal antibodies specific for canine CD138 (syndecan-1) for nuclear medicine preclinical trials on spontaneous tumours

Autor: François Davodeau, Caroline Rousseau, Joëlle Gaschet, Jérôme Abadie, Catherine Ibisch, E. Verger, M. Berthaud, Catherine Maurel, F. Nguyen, M. Diab, Michel Chérel

Publikováno v: Veterinary and Comparative Oncology. 15:932-951

We isolated 11 antibodies specific for canine CD138 (cCD138) to validate the interest of CD138 antigen targeting in dogs with spontaneous mammary carcinoma. The affinity of the monoclonal antibodies in the nanomolar range is suitable for immunohistoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75b63ecef0846ec272d5b68e0d2ee8fc
https://doi.org/10.1111/vco.12233

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Efficacy of Astatine-211 radioimmunotherapy of Multiple Myeloma using an anti-mCD138 monoclonal antibody in a syngeneic murine model

Autor: Sébastien Gouard, Benjamin Chalopin, Catherine Saï-Maurel, François Guérard, Laurent Navarro, jean-françois GESTIN, Nicolas Chouin, Ferid Haddad, Cyrille Alliot, Françoise Kraeber-Bodéré, François Davodeau, Michel Chérel

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging
EANM 2018: 31st Annual Congress of the European Association of Nuclear Medicine
European Journal of Nuclear Medicine and Molecular Imaging, Springer Verlag (Germany), 2018, 45 (1), pp.S166-S167
Publons
Web of Science
HAL
European Journal of Nuclear Medicine and Molecular Imaging, 2018, 45 (1), pp.S166-S167

s of Annual Congress of the European Association of Nuclear Medicine October 13 – 17, 2018 Düsseldorf, Germany; International audience; Aim: Multiple myeloma is a B-cell malignancy of terminally differentiated plasma cells within the bone marrow.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5bdf0d50705d203b648e1517a1b47162
https://www.hal.inserm.fr/inserm-02341491/document

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Radioimmunoconjugates for the Treatment of Cancer

Autor: Michel Chérel, Jacques Barbet, Joëlle Gaschet, Jean-François Gestin, Amandine Pallardy, Thomas Carlier, François Davodeau, Alain Faivre-Chauvet, Françoise Kraeber-Bodéré, Caroline Rousseau, Caroline Bodet-Milin, Ludovic Ferrer, T. Eugène, Eric Frampas

Publikováno v: Seminars in Oncology. 41:613-622

Radioimmunotherapy (RIT) has been developed for more than 30 years. Two products targeting the CD20 antigen are approved in the treatment of non-Hodgkin B-cell lymphoma (NHBL): iodine 131-tositumomab and yttrium 90-ibritumomab tiuxetan. RIT can be in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd276f2696d5375a7f7da1b4f706f28f
https://doi.org/10.1053/j.seminoncol.2014.07.004

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Comparative analysis of multiple myeloma treatment by CD138 antigen targeting with bismuth-213 and Melphalan chemotherapy

Autor: Joëlle Gaschet, Alain Faivre-Chauvet, A. Pallardy, Catherine Maurel, François Davodeau, E. Matous, F. Kraeber-Bodéré, Frank Bruchertseifer, Michel Chérel, Alfred Morgenstern, Sébastien Gouard

Publikováno v: Nuclear Medicine and Biology. 41:e30-e35

Introduction Multiple myeloma (MM) is a B-cell malignancy of terminally differentiated plasma cells within the bone marrow. Despite intense research to develop new treatments, cure is almost never achieved. Alpha-radioimmunotherapy (RIT) has been sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967be196b8284a6a07b07bda5166f007
https://doi.org/10.1016/j.nucmedbio.2014.02.008

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[Alpha-Radioimmunotherapy: principle and relevance in anti-tumor immunity]

Autor: Jérémie, Ménager, Jean-Baptiste, Gorin, Nolwenn, Fichou, Sébastien, Gouard, Alfred, Morgenstern, Frank, Bruchertseifer, François, Davodeau, Françoise, Kraeber-Bodéré, Michel, Chérel, Joëlle, Gaschet, Yannick, Guilloux

Publikováno v: Medecine sciences : M/S. 32(4)

Alpha-radioimmunotherapy (α-RIT) is a targeted anti-tumor therapy using usually a monoclonal antibody specific for a tumor antigen that is coupled to an α-particle emitter. α-emitters represent an ideal tool to eradicate disseminated tumors or met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76c2aee3fad869ddb6fcc4fcb31f27b4
https://pubmed.ncbi.nlm.nih.gov/27137693

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