Zobrazeno 1 - 10
of 139
pro vyhledávání: '"François, Bénard"'
Autor:
Sara Harsini, Patrick Martineau, Sonia Plaha, Heather Saprunoff, Catherine Chen, Julia Bishop, Scott Tyldesley, Don Wilson, François Bénard
Publikováno v:
Cancer Imaging, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) is becoming standard of care for men with biochemical recurrence (BCR) of prostate cancer. The implications of a negative PSMA PET
Externí odkaz:
https://doaj.org/article/fc63f15514ae4d34906295b7b16f298f
Autor:
Lei Wang, Hsiou-Ting Kuo, Zhengxing Zhang, Chengcheng Zhang, Chao-Cheng Chen, Devon Chapple, Ryan Wilson, Nadine Colpo, François Bénard, Kuo-Shyan Lin
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Background Overexpressed in various solid tumors, gastrin-releasing peptide receptor (GRPR) is a promising cancer imaging marker and therapeutic target. Although antagonists are preferable for the development of GRPR-targeted radiopharmaceut
Externí odkaz:
https://doaj.org/article/24ff8b25475b4173968a9c483ac5e550
Autor:
Marin Simunic, Jay T. Joshi, Helen Merkens, Nadine Colpo, Hsiou-Ting Kuo, Julian J. Lum, François Bénard
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-7 (2024)
Externí odkaz:
https://doaj.org/article/d7a3c8e0d16a4df99867cf7dee5f8f2d
Autor:
Parmissa Randhawa, Imma Carbo-Bague, Patrick R. W. J. Davey, Shaohuang Chen, Helen Merkens, Carlos F. Uribe, Chengcheng Zhang, Marianna Tosato, François Bénard, Valery Radchenko, Caterina F. Ramogida
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
A comprehensive investigation of the Hg2+ coordination chemistry and 197m/gHg radiolabeling capabilities of cyclen-based commercial chelators, namely, DOTA and DOTAM (aka TCMC), along with their bifunctional counterparts, p-SCN-Bn-DOTA and p-SCN-Bn-T
Externí odkaz:
https://doaj.org/article/2d2c5a23232b4b0aa52bcf207a58b8ad
Autor:
Nancy Guo, Aijun Yang, Fabiha Binte Farooq, Shreena Kalaria, Elena Moss, Lindsay DeVorkin, Mary Lesperance, François Bénard, Don Wilson, Anna V. Tinker, Farouk S. Nathoo, Phineas T. Hamilton, Julian J. Lum
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Unlike other histological types of epithelial ovarian carcinoma, clear cell ovarian carcinoma (CCOC) has poor response to therapy. In many other carcinomas, expression of the hypoxia-related enzyme Carbonic anhydrase IX (CAIX) by cancer cell
Externí odkaz:
https://doaj.org/article/95ede8de1ca14914bdce66a61cd611f5
Autor:
Lei Wang, Hsiou-Ting Kuo, Chao-Cheng Chen, Devon Chapple, Nadine Colpo, Pauline Ng, Wing Sum Lau, Shireen Jozi, François Bénard, Kuo-Shyan Lin
Publikováno v:
Molecules, Vol 29, Iss 13, p 3102 (2024)
Gastrin-releasing peptide receptor (GRPR), overexpressed in many solid tumors, is a promising imaging marker and therapeutic target. Most reported GRPR-targeted radioligands contain a C-terminal amide. Based on the reported potent antagonist D-Phe-Gl
Externí odkaz:
https://doaj.org/article/90a3007f690d4f83bd84d2472d76249b
Autor:
Lei Wang, Chao-Cheng Chen, Zhengxing Zhang, Hsiou-Ting Kuo, Chengcheng Zhang, Nadine Colpo, Helen Merkens, François Bénard, Kuo-Shyan Lin
Publikováno v:
Pharmaceuticals, Vol 17, Iss 5, p 621 (2024)
Gastrin-releasing peptide receptor (GRPR) is overexpressed in various cancers and is a promising target for cancer diagnosis and therapy. However, the high pancreas uptake and/or metabolic instability observed for most reported GRPR-targeted radiolig
Externí odkaz:
https://doaj.org/article/16c02e200e2b477db4930b5913cbb995
Autor:
Sara Harsini, Don Wilson, Heather Saprunoff, Hayley Allan, Martin Gleave, Larry Goldenberg, Kim N. Chi, Charmaine Kim-Sing, Scott Tyldesley, François Bénard
Publikováno v:
Cancer Imaging, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Radiotherapy (RT) and surgery are potential treatment options in patients with biochemical recurrence (BCR) following primary prostate cancer treatment. This study examines the value of prostate-specific membrane antigen (PSMA) po
Externí odkaz:
https://doaj.org/article/5f8751b6c9444577adc256ab103c63e4
Autor:
Scott W. McNeil, Michiel Van de Voorde, Chengcheng Zhang, Maarten Ooms, François Bénard, Valery Radchenko, Hua Yang
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 7, Iss 1, Pp 1-17 (2022)
Abstract Background 161Tb is a radiolanthanide with the potential to replace 177Lu in targeted radionuclide therapy. 161Tb is produced via the neutron irradiation of [160Gd]Gd2O3 targets, and must be purified from 160Gd and the decay product 161Dy pr
Externí odkaz:
https://doaj.org/article/52199cec9dcf42fbae361825ab1fe278
Autor:
Arsyangela Verena, Helen Merkens, Chao-Cheng Chen, Devon E. Chapple, Lei Wang, Shreya Bendre, Antonio A. W. L. Wong, François Bénard, Kuo-Shyan Lin
Publikováno v:
Molecules, Vol 29, Iss 4, p 800 (2024)
Some bispecific radiotracers have been developed to overcome the limitations of monospecific tracers and improve detection sensitivity for heterogeneous tumor lesions. Here, we aim to synthesize two bispecific tracers targeting prostate-specific memb
Externí odkaz:
https://doaj.org/article/faeba61c8ec04d788d0dcd4a501cd17d