The new nitric oxide donor cyclohexane nitrate induces vasorelaxation, hypotension, and antihypertensive effects via NO/cGMP/PKG pathway.

Autor: Mendes-Júnior Ld; Biotechnology Center, Federal University of Paraíba João Pessoa, Brazil., Guimarães DD; Biotechnology Center, Federal University of Paraíba João Pessoa, Brazil., Gadelha DD; Biotechnology Center, Federal University of Paraíba João Pessoa, Brazil., Diniz TF; Department of Physiology and Biophysics, Institute of Biological Sciences, Federal University of Minas Gerais Belo Horizonte, Brazil., Brandão MC; Department of Chemistry, Federal University of Paraíba João Pessoa, Brazil., Athayde-Filho PF; Department of Chemistry, Federal University of Paraíba João Pessoa, Brazil., Lemos VS; Department of Physiology and Biophysics, Institute of Biological Sciences, Federal University of Minas Gerais Belo Horizonte, Brazil., França-Silva Mdo S; Biotechnology Center, Federal University of Paraíba João Pessoa, Brazil., Braga VA; Biotechnology Center, Federal University of Paraíba João Pessoa, Brazil.

Publikováno v: Frontiers in physiology [Front Physiol] 2015 Aug 31; Vol. 6, pp. 243. Date of Electronic Publication: 2015 Aug 31 (Print Publication: 2015).