A multifaceted approach towards understanding the peculiar behavior of (α)-hydroxyiminophosphonates

Autor: Jean-Christophe Monbaliu, Loïc Quinton, Thomas Toupy, Kristof Van Hecke, Christopher Kune

Publikováno v: Organic Chemistry Frontiers. 9:173-182

The peculiar isomer-selective reduction of (α)-hydroxyiminophosphonates (oxime isomers) into (α)-hydroxyaminophosphonate (hydroxylamine) derivatives is presented. A library of 16 (α)-hydroxyiminophosphonates is prepared and studied via a unique mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::05defd8a4de8c166de0061fb6a8a7610
https://doi.org/10.1039/d1qo01564h

Characterization of Mycobacterium tuberculosis Mycolic Acids by Multiple-Stage Linear Ion-Trap Mass Spectrometry

Autor: Hideji Fujiwara, Spencer J. Williams, Cheryl Frankfater, Adriaan J. Minnaard, Fong-Fu Hsu

Publikováno v: Journal of the American Society for Mass Spectrometry, 33(1). SPRINGER

Mycobacterium tuberculosis (Mtb) cells are known to synthesize very long chain (C60-90) structurally complex mycolic acids with various functional groups. In this study, we applied linear ion-trap (LIT) multiple-stage mass spectrometry (MSn), combine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6a02bdcddbb1f1fb6a29806b4b6967
https://doi.org/10.1021/jasms.1c00310

Disentangling Lipid Isomers by High-Resolution Differential Ion Mobility Spectrometry/Ozone-Induced Dissociation of Metalated Species

Autor: Alexandre A. Shvartsburg, Berwyck L. J. Poad, Stephen J. Blanksby, Francis Berthias, Hayden A. Thurman, Andrew P. Bowman

Publikováno v: Journal of the American Society for Mass Spectrometry. 32:2827-2836

The preponderance and functional importance of isomeric biomolecules have become topical in biochemistry. Therefore, one must distinguish and identify all such forms across compound classes, over a wide dynamic range as minor species often have criti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7618158be1376f2bb938df9aae3ab0e8
https://doi.org/10.1021/jasms.1c00251

Efficient Isothiocyanate Modification of Peptides Facilitates Structural Analysis by Radical-Directed Dissociation

Autor: Tyler R. Lambeth, Ryan R. Julian

Publikováno v: Journal of the American Society for Mass Spectrometry. 33:1338-1345

Radical-directed dissociation (RDD) is a powerful technique for structural characterization of peptides in mass spectrometry experiments. Prior to analysis, a radical precursor must typically be appended to facilitate generation of a free radical. To

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8120f8900d439d4cccd8897d0111ea98
https://doi.org/10.1021/jasms.1c00237

Ionization of 2‐ and 4(5)‐Nitroimidazoles Radiosensitizers: A 'Kinetic Competition' Between NO 2 and NO Losses

Autor: Lorenzo Avaldi, Paola Bolognesi, Jacopo Chiarinelli, Mauro Satta, Antonella Cartoni, Daniele Catone, Anna Rita Casavola, Stefano Borocci, Mattea Carmen Castrovilli

Publikováno v: ChemPhysChem
22 (2021): 2387–2391. doi:10.1002/cphc.202100629
info:cnr-pdr/source/autori:Satta, Mauro; Casavola, Anna Rita; Cartoni, Antonella; Castrovilli, Mattea Carmen; Catone, Daniele; Chiarinelli, Jacopo; Borocci, Stefano; Avaldi, Lorenzo; Bolognesi, Paola/titolo:Ionization of 2-and 4(5)-Nitroimidazoles Radiosensitizers: a "Kinetic Competition" Between NO2 and NO Losses/doi:10.1002%2Fcphc.202100629/rivista:ChemPhysChem (Print)/anno:2021/pagina_da:2387/pagina_a:2391/intervallo_pagine:2387–2391/volume:22

Nitroimidazoles are a class of chemicals with a remarkable broad spectrum of applications from the production of explosives to the use as radiosensitizers in radiotherapy. The understanding of thedynamics of their fragmentation induced by ionizing so

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6b86475f332b9f19172ddbe9f93fa6
https://doi.org/10.1002/cphc.202100629