Výsledky vyhledávání - "FragXis Study Group"

Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results

Autor: Youssef, Eriene A, Berry-Kravis, Elizabeth, Czech, Christian, Hagerman, Randi J, Hessl, David, Wong, Chin Y, Rabbia, Michael, Deptula, Dennis, John, Amy, Kinch, Russell, Drewitt, Philip, Lindemann, Lothar, Marcinowski, Moritz, Langland, Rachel, Horn, Carsten, Fontoura, Paulo, Santarelli, Luca, Quiroz, Jorge A, FragXis Study Group

Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol 43, iss 3

Preclinical data suggest that inhibition of the metabotropic glutamate receptor 5 (mGluR5) receptor might hold therapeutic benefits in Fragile X syndrome (FXS). Treatment of Fmr1 knockout mice with mGluR5-negative allosteric modulators (NAMs) has bee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7185f25043980ec818aed96cdd8dbc50
https://escholarship.org/uc/item/7mn4c9f6

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