Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Fraction K Dzinjalamala"'
Autor:
Miriam K Laufer, Phillip C Thesing, Fraction K Dzinjalamala, Osward M Nyirenda, Rhoda Masonga, Matthew B Laurens, Abbie Stokes-Riner, Terrie E Taylor, Christopher V Plowe
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42284 (2012)
The predominance of chloroquine-susceptible falciparum malaria in Malawi more than a decade after chloroquine's withdrawal permits contemplation of re-introducing chloroquine for targeted uses. We aimed to compare the ability of different partner dru
Externí odkaz:
https://doaj.org/article/643831e292fb432594186a5d25d1e77b
Autor:
Gretchen L. Birbeck, Susan T. Herman, Edmund V. Capparelli, Fraction K. Dzinjalamala, Samah G. Abdel Baki, Macpherson Mallewa, Neema M. Toto, Douglas G. Postels, Joseph C. Gardiner, Terrie E. Taylor, Karl B. Seydel
Publikováno v:
BMC Pediatrics, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Acute seizures are common in pediatric cerebral malaria (CM), but usual care with phenobarbital risks respiratory suppression. We undertook studies of enteral levetiracetam (eLVT) to evaluate pharmacokinetics (PK), safety and effi
Externí odkaz:
https://doaj.org/article/6600377b119e4395bbbb1702f9b8751d
Autor:
Gerry Davies, Alessandro Schipani, Elizabeth Molyneux, Steve A. Ward, Rachel Mlota, Fraction K. Dzinjalamala, Saye Khoo, Henry Pertinez, Joep J. van Oosterhout, Nuria Lopez
Publikováno v:
British Journal of Clinical Pharmacology. 81:679-687
AIMS Low rifampicin plasma concentrations can lead to treatment failure and increased risk of developing drug resistant tuberculosis. The objectives of this study were to characterize the population pharmacokinetics (popPK) of rifampicin in Malawian
Autor:
Mavuto Mukaka, Jane Mallewa, Victor Maiden, Dianne J. Terlouw, David G. Lalloo, Fraction K. Dzinjalamala, Victor Mwapasa, Saye Khoo, Clifford G. Banda
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62(11)
There is conflicting evidence of the impact of commonly used antiretroviral therapies (ARTs) on the pharmacokinetics of lumefantrine and safety profile of artemether-lumefantrine. We compared the area under the concentration-time curve (AUC0-14 days)
Autor:
Mwayi Madanitsa, Ebbie Chaluluka, Feiko O. ter Kuile, Kyaw L. Thwai, Steve Meshnick, Carole Khairallah, Ya Ping Shi, Don P. Mathanga, Steve M. Taylor, Ryan E. Wiegand, Jacek Skarbinski, Dyson Mwandama, Zhiyong Zhou, Fraction K. Dzinjalamala, Doreen Ali, Linda Kalilani, Julie Gutman
Publikováno v:
Journal of infectious diseases, 211(12), 1997-2005. Oxford University Press
Background. The A581G mutation in the gene encoding Plasmodium falciparum dihydropteroate synthase (dhps), in combination with the quintuple mutant involving mutations in both dhps and the gene encoding dihydrofolate reductase (dhfr), the so-called s
Autor:
Jacek Skarbinski, Cassidy W. Claassen, Shannon Takala-Harrison, Anne E. P. Frosch, Miriam K. Laufer, Don P. Mathanga, Fraction K. Dzinjalamala, Christopher V. Plowe
Publikováno v:
The Journal of Infectious Diseases. 210:1110-1114
Background. The return of chloroquine-sensitive Plasmodium falciparum to the limited area of Blantyre, Malawi, has been well demonstrated in several studies. Methods. To characterize chloroquine susceptibility over a wide geographic area, infants and
Autor:
Fraction K. Dzinjalamala, O. Colin Stine, Christopher V. Plowe, Shannon Takala-Harrison, Miriam K. Laufer, Terrie E. Taylor
Publikováno v:
The Journal of Infectious Diseases. 202:801-808
The spread of drug-resistant Plasmodium falciparum malaria has been a major impediment to malaria control and threatens prospects for elimination. We recently demonstrated the return of chloroquine-susceptible malaria in Malawi after chloroquine use
Autor:
Phillip C. Thesing, Lorraine Beraho, Stephen M. Graham, Christopher V. Plowe, Teresa Hsi, Fraction K. Dzinjalamala, Terrie E. Taylor, Joep J. van Oosterhout, Miriam K. Laufer
Publikováno v:
Scopus-Elsevier
American Journal of Tropical Medicine and Hygiene, 77, 4, pp. 627-32
American Journal of Tropical Medicine and Hygiene, 77, 627-32
American Journal of Tropical Medicine and Hygiene, 77, 4, pp. 627-32
American Journal of Tropical Medicine and Hygiene, 77, 627-32
Identification of an effect of HIV-associated immunosuppression on response to antimalarial therapy would help guide management of malaria infection in areas of high HIV prevalence. Therefore, we conducted an observational study of people living with
Autor:
Miriam K. Laufer, James G. Kublin, Elena Artimovich, Shannon Takala-Harrison, Kristan A. Schneider, Ananias A. Escalante, Christopher V. Plowe, Fraction K. Dzinjalamala, Terrie E. Taylor
Background. In 2007, Malawi replaced sulfadoxine-pyrimethamine (SP) with an artemisinin-based combination therapy as the first-line treatment for uncomplicated Plasmodium falciparum malaria in response to failing SP efficacy. Here we estimate the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d41aa9ad45fc77f4d38fc35340f39a
https://europepmc.org/articles/PMC4539899/
https://europepmc.org/articles/PMC4539899/
Autor:
Shannon L. Takala, Fraction K. Dzinjalamala, Nicole D. Eddington, Phillip C. Thesing, Miriam K. Laufer, Christopher V. Plowe, Rhoda Masonga, Terrie E. Taylor
Publikováno v:
New England Journal of Medicine. 355:1959-1966
BACKGROUND In 1993, Malawi became the first country in Africa to replace chloroquine with the combination of sulfadoxine and pyrimethamine for the treatment of malaria. At that time, the clinical efficacy of chloroquine was less than 50%. The molecul