Emergence of activation or repression in transcriptional control under a fixed molecular context.

Autor: Martinez-Corral R; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.; Centre for Genomic Regulation, Barcelona Collaboratorium for Modelling and Predictive Biology, 08003, Barcelona, SPAIN., Friedrich D; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.; Present address: Bayer AG Pharmaceuticals, 51368 Leverkusen, Germany., Frömel R; Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona 08003, SPAIN.; Universitat Pompeu Fabra (UPF), Barcelona, SPAIN., Velten L; Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona 08003, SPAIN.; Universitat Pompeu Fabra (UPF), Barcelona, SPAIN., Gunawardena J; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA., DePace AH; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.; Howard Hughes Medical Institute.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 02. Date of Electronic Publication: 2024 Jun 02.

Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cells.

Autor: Sarropoulos I; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, D-69120 Heidelberg, Germany. h.kaessmann@zmbh.uni-heidelberg.de s.pfister@dkfz.de i.sarropoulos@zmbh.uni-heidelberg.de m.sepp@zmbh.uni-heidelberg.de., Sepp M; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, D-69120 Heidelberg, Germany. h.kaessmann@zmbh.uni-heidelberg.de s.pfister@dkfz.de i.sarropoulos@zmbh.uni-heidelberg.de m.sepp@zmbh.uni-heidelberg.de., Frömel R; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, D-69120 Heidelberg, Germany., Leiss K; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, D-69120 Heidelberg, Germany., Trost N; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, D-69120 Heidelberg, Germany., Leushkin E; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, D-69120 Heidelberg, Germany., Okonechnikov K; Hopp Children's Cancer Center (KiTZ) Heidelberg, Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), and German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany., Joshi P; Hopp Children's Cancer Center (KiTZ) Heidelberg, Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), and German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany., Giere P; Museum für Naturkunde, Leibniz Institute for Evolution and Biodiversity Science, Berlin, Germany., Kutscher LM; Hopp Children's Cancer Center (KiTZ) Heidelberg, Developmental Origins of Pediatric Cancer Group, German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany., Cardoso-Moreira M; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, D-69120 Heidelberg, Germany.; Evolutionary Developmental Biology Laboratory, Francis Crick Institute, London NW1 1AT, UK., Pfister SM; Hopp Children's Cancer Center (KiTZ) Heidelberg, Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), and German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany. h.kaessmann@zmbh.uni-heidelberg.de s.pfister@dkfz.de i.sarropoulos@zmbh.uni-heidelberg.de m.sepp@zmbh.uni-heidelberg.de.; Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany., Kaessmann H; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, D-69120 Heidelberg, Germany. h.kaessmann@zmbh.uni-heidelberg.de s.pfister@dkfz.de i.sarropoulos@zmbh.uni-heidelberg.de m.sepp@zmbh.uni-heidelberg.de.

Publikováno v: Science (New York, N.Y.) [Science] 2021 Aug 27; Vol. 373 (6558). Date of Electronic Publication: 2021 Jul 29.

Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics.

Autor: Velten L; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain. lars.velten@crg.eu.; Universitat Pompeu Fabra (UPF), Barcelona, Spain. lars.velten@crg.eu., Story BA; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.; Swiss Federal Institute of Technology (ETH) Zurich, Department of Biosystems Science and Engineering, Basel, Switzerland., Hernández-Malmierca P; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany., Raffel S; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany., Leonce DR; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany., Milbank J; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany., Paulsen M; European Molecular Biology Laboratory (EMBL), Flow Cytometry Core Facility, Heidelberg, Germany., Demir A; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany., Szu-Tu C; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Frömel R; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Lutz C; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany., Nowak D; Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Jann JC; Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Pabst C; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.; Molecular Medicine Partnership Unit (MMPU), University of Heidelberg and European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Boch T; Swiss Federal Institute of Technology (ETH) Zurich, Department of Biosystems Science and Engineering, Basel, Switzerland.; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Hofmann WK; Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Müller-Tidow C; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany., Trumpp A; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany., Haas S; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany.; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; Berlin Institute of Health (BIH), Berlin, Germany.; Charité-Universitätsmedizin, Berlin, Germany.; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany., Steinmetz LM; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany. larsms@embl.de.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. larsms@embl.de.; Stanford Genome Technology Center, Palo Alto, CA, USA. larsms@embl.de.

Publikováno v: Nature communications [Nat Commun] 2021 Mar 01; Vol. 12 (1), pp. 1366. Date of Electronic Publication: 2021 Mar 01.

Epithelial–Mesenchymal Transition in Acute Leukemias.

Autor: Varisli, Lokman¹ (AUTHOR), Vlahopoulos, Spiros² (AUTHOR) sblachop@med.uoa.gr

Publikováno v: International Journal of Molecular Sciences. Feb2024, Vol. 25 Issue 4, p2173. 20p.

Characterization of Single-Cell Cis-regulatory Elements Informs Implications for Cell Differentiation.

Autor: Ren, Ying-Ying, Liu, Zhen

Publikováno v: Genome Biology & Evolution; Nov2024, Vol. 16 Issue 11, p1-14, 14p