Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Fréderique Magdinier"'
Autor:
Nausica Arnoult, Caroline Schluth-Bolard, Anne Letessier, Irena Drascovic, Rachida Bouarich-Bourimi, Judith Campisi, Sahn-Ho Kim, Amina Boussouar, Alexandre Ottaviani, Frédérique Magdinier, Eric Gilson, Arturo Londoño-Vallejo
Publikováno v:
PLoS Genetics, Vol 6, Iss 4, p e1000920 (2010)
The mechanisms governing telomere replication in humans are still poorly understood. To fill this gap, we investigated the timing of replication of single telomeres in human cells. Using in situ hybridization techniques, we have found that specific t
Externí odkaz:
https://doaj.org/article/3e341172847d40159be7b61dc626ac57
Autor:
Chiara Uboldi, Marcos Sanles Sobrido, Elodie Bernard, Virginie Tassistro, Nathalie Herlin-Boime, Dominique Vrel, Sébastien Garcia-Argote, Stéphane Roche, Fréderique Magdinier, Gheorghe Dinescu, Véronique Malard, Laurence Lebaron-Jacobs, Jerome Rose, Bernard Rousseau, Philippe Delaporte, Christian Grisolia, Thierry Orsière
Publikováno v:
Nanomaterials, Vol 9, Iss 9, p 1233 (2019)
Tungsten was chosen as a wall component to interact with the plasma generated by the International Thermonuclear Experimental fusion Reactor (ITER). Nevertheless, during plasma operation tritiated tungsten nanoparticles (W-NPs) will be formed and pot
Externí odkaz:
https://doaj.org/article/bbca4492531c4e7bb9ce1d2dd92ccb0e
Autor:
Julien Van Gils, Slim Karkar, Aurélien Barre, Seyta Ley-Ngardigal, Sophie Nothof, Stéphane Claverol, Caroline Tokarski, Jean-Philippe Trani, Raphael Chevalier, Natacha Broucqsault, Claire El Yazidi, Didier Lacombe, Patricia Fergelot, Frédérique Magdinier
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Rubinstein-Taybi syndrome (RTS) is a rare and severe genetic developmental disorder characterized by multiple congenital anomalies and intellectual disability. CREBBP and EP300, the two genes known to cause RTS encode transcriptional coactiv
Externí odkaz:
https://doaj.org/article/5ca15b01bb7840f3b1cb9bd06d1fa239
Autor:
Alizée Sebastian, Monique Silvy, Benjamin Coiffard, Martine Reynaud-Gaubert, Frédérique Magdinier, Jacques Chiaroni, Christophe Picard, Pascal Pedini
Publikováno v:
Frontiers in Transplantation, Vol 3 (2024)
IntroductionCirculating cell-free DNA (cfDNA) is emerging as a non-invasive biomarker in solid organ transplantation (SOT) monitoring and data on its diagnostic potential have been increasing in recent years. This review aims to summarize the main ad
Externí odkaz:
https://doaj.org/article/7083ba869df34d05a0e578be9540d58f
Autor:
Hager Jaouadi, Victor Morel, Helene Martel, Pierre Lindenbaum, Lorcan Lamy de la Chapelle, Marine Herbane, Claire Lucas, Frédérique Magdinier, Habib Gilbert, Jean-Jacques Schott, Stéphane Zaffran, Karine Nguyen
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundApproximately half of hypertrophic cardiomyopathy (HCM) patients lack a precise genetic diagnosis. The likelihood of identifying clinically relevant variants increased over time.MethodsIn this study, we conducted a gene-centric reanalysis o
Externí odkaz:
https://doaj.org/article/130cb58808844f979f98d6641a127d63
Autor:
Maria Sol Jacome Burbano, Jérôme D. Robin, Serge Bauwens, Marjorie Martin, Emma Donati, Lucia Martínez, Peipei Lin, Sabrina Sacconi, Frédérique Magdinier, Eric Gilson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Telomeric repeat binding factor 2 (TRF2) binds to telomeres and protects chromosome ends against the DNA damage response and senescence. Although the expression of TRF2 is downregulated upon cellular senescence and in various aging tissues,
Externí odkaz:
https://doaj.org/article/d600b22df10d459d9d7664b5a9e0f266
Autor:
Shifeng Xue, Thanh Thao Nguyen Ly, Raunak S. Vijayakar, Jingyi Chen, Joel Ng, Ajay S. Mathuru, Frederique Magdinier, Bruno Reversade
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Hox genes are known to control anteroposterior patterning, including the vertebrate spine. Here Xue et al. show that maternal Smchd1 regulates Hox expression in an epigenetic manner, and that wild type offspring from heterozygous mothers show skeleta
Externí odkaz:
https://doaj.org/article/4b6dee71e17346d4bd2f45a200af55bd
Autor:
Camille Laberthonnière, Elva‐Maria Novoa‐del‐Toro, Mégane Delourme, Raphaël Chevalier, Natacha Broucqsault, Kilian Mazaleyrat, Nathalie Streichenberger, Véronique Manel, Rafaëlle Bernard, Emmanuelle Salort Campana, Shahram Attarian, Karine Nguyen, Jérôme D. Robin, Anais Baudot, Frédérique Magdinier
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 621-635 (2022)
Abstract Background Facioscapulohumeral dystrophy (FSHD) is a late‐onset autosomal dominant form of muscular dystrophy involving specific groups of muscles with variable weakness that precedes inflammatory response, fat infiltration, and muscle atr
Externí odkaz:
https://doaj.org/article/8f932ee1e4384c53a16531a5f4c02563
Autor:
Laetitia Dard, Christophe Hubert, Pauline Esteves, Wendy Blanchard, Ghina Bou About, Lyla Baldasseroni, Elodie Dumon, Chloe Angelini, Mégane Delourme, Véronique Guyonnet-Dupérat, Stéphane Claverol, Laura Fontenille, Karima Kissa, Pierre-Emmanuel Séguéla, Jean-Benoît Thambo, Lévy Nicolas, Yann Herault, Nadège Bellance, Nivea Dias Amoedo, Frédérique Magdinier, Tania Sorg, Didier Lacombe, Rodrigue Rossignol
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 8 (2022)
Germline mutations that activate genes in the canonical RAS/MAPK signaling pathway are responsible for rare human developmental disorders known as RASopathies. Here, we analyzed the molecular determinants of Costello syndrome (CS) using a mouse model
Externí odkaz:
https://doaj.org/article/efecf1351ff2484ba90767b2754d4938
Autor:
Diane Frankel, Valérie Delecourt, Elva-María Novoa-del-Toro, Jérôme D. Robin, Coraline Airault, Catherine Bartoli, Aurélie Carabalona, Sophie Perrin, Kilian Mazaleyrat, Annachiara De Sandre-Giovannoli, Frederique Magdinier, Anaïs Baudot, Nicolas Lévy, Elise Kaspi, Patrice Roll
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103757- (2022)
Summary: Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder, in which an abnormal and toxic protein called progerin, accumulates in cell nuclei, leading to major cellular defects. Among them, chromatin remodeling drives gene expre
Externí odkaz:
https://doaj.org/article/1068381b12894a3784d9ad1250954c43