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Bronchial Remodeling-based Latent Class Analysis Predicts Exacerbations in Severe Preschool Wheezers
Autor:
Michael Fayon, Fabien Beaufils, Pauline Esteves, Maryline Campagnac, Elise Maurat, Marine Michelet, Valerie Siao-Him-Fa, Frederic Lavrand, Guillaume Simon, Hugues Begueret, Patrick Berger, Françoise Auriol, Sylvain Blanchon, Dominique Carles, Vincent Boisserie-Lacroix, François Brémont, Stéphanie Bui, Marie-Luce Choukroun, Stéphane Debelleix, Hala Feghali, Géraldine Labouret, Audrey Martin Blondel, Sébastien Marais, Marie Mittaine, Fabienne Nacka, Olga Ousova, Isabelle Rouquette, François Semjen, Frédérique Sgoifo, Thomas Trian
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 207:416-426
Children with preschool wheezing represent a very heterogeneous population with wide variability regarding their clinical, inflammatory, obstructive, and/or remodeling patterns. We hypothesized that assessing bronchial remodeling would help clinician