Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Frédérique Braun"'
Autor:
Jessie Pécot, Laurent Maillet, Janic Le Pen, Céline Vuillier, Sophie de Carné Trécesson, Aurélie Fétiveau, Kristopher A. Sarosiek, Florian J. Bock, Frédérique Braun, Anthony Letai, Stephen W.G. Tait, Fabien Gautier, Philippe P. Juin
Publikováno v:
Cell Reports, Vol 17, Iss 12, Pp 3347-3358 (2016)
Anti-apoptotic BCL-2 family members bind to BH3-only proteins and multidomain BAX/BAK to preserve mitochondrial integrity and maintain survival. Whereas inhibition of these interactions is the biological basis of BH3-mimetic anti-cancer therapy, the
Externí odkaz:
https://doaj.org/article/4eb4166ad1e942d9be0e2a92a8e876df
Publikováno v:
eLife, Vol 6 (2017)
Post-transcriptional control by small regulatory RNA (sRNA) is critical for rapid adaptive processes. sRNAs can directly modulate mRNA degradation in Proteobacteria without interfering with translation. However, Firmicutes have a fundamentally differ
Externí odkaz:
https://doaj.org/article/9d7514fd183a4110ac30ecc87d0692c2
Autor:
Sylvain Durand, Frédérique Braun, Efthimia Lioliou, Cédric Romilly, Anne-Catherine Helfer, Laurianne Kuhn, Noé Quittot, Pierre Nicolas, Pascale Romby, Ciarán Condon
Publikováno v:
PLoS Genetics, Vol 11, Iss 2, p e1004957 (2015)
RsaE is the only known trans-acting small regulatory RNA (sRNA) besides the ubiquitous 6S RNA that is conserved between the human pathogen Staphylococcus aureus and the soil-dwelling Firmicute Bacillus subtilis. Although a number of RsaE targets are
Externí odkaz:
https://doaj.org/article/781e319b3a3c4bd5b91bab1f07daa1c6
Autor:
Frédérique Braun, Joséphine Bertin-Ciftci, Anne-Sophie Gallouet, Julie Millour, Philippe Juin
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23577 (2011)
The cyclin-dependent kinase inhibitor p21 (p21WAF1/Cip1) is a multifunctional protein known to promote cell cycle arrest and survival in response to p53-dependent and p53 independent stimuli. We herein investigated whether and how it might contribute
Externí odkaz:
https://doaj.org/article/932e3a96b1bf4d789c7ecafe3dcb8edf
Publikováno v:
Microbiology Spectrum. 11
The passage of ribosomes across individual mRNAs during translation can have different effects on their degradation, ranging from a protective effect by shielding from ribonucleases to, in some cases, making the mRNA more vulnerable to RNase action.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85c3662d3da773e04f6d794832c97e0f
https://doi.org/10.1128/spectrum.05134-22
https://doi.org/10.1128/spectrum.05134-22
Autor:
James C. Taggart, Jean-Benoit Lalanne, Sylvain Durand, Frédérique Braun, Ciarán Condon, Gene-Wei Li
RNA endonucleases are the rate-limiting initiator of decay for many bacterial mRNAs. Subsequent decay by exonucleases typically obscures these cleavage events, and even for the well-studiedBacillus subtilis, few precise positions of cleavage have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b43149fa71770a80e1e06c1cc604818f
https://doi.org/10.1101/2023.03.12.532304
https://doi.org/10.1101/2023.03.12.532304
Autor:
Valentin Deves, Aude Trinquier, Laetitia Gilet, Jawad Alharake, Magali Leroy, Ciarán Condon, Frédérique Braun
Rae1 is a well-conserved endoribonuclease among Gram-positive bacteria, cyanobacteria and the chloroplasts of higher plants. We have previously shown that Rae1 cleaves theBacillus subtilis yrzIoperon mRNA in a translation-dependent manner, within a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06955c2a6df4623326e3c6d26050196f
https://doi.org/10.1101/2023.02.16.528812
https://doi.org/10.1101/2023.02.16.528812
The impact of translation on mRNA stability can be varied, ranging from a protective effect of ribosomes that shield mRNA from ribonucleases (RNases), to preferentially exposing sites of RNase cleavage. These effects can change depending on whether r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07415ea6fd175b6be7bdada2a944920b
https://doi.org/10.1101/2022.11.23.517781
https://doi.org/10.1101/2022.11.23.517781
Publikováno v:
Comptes Rendus Biologies
Comptes Rendus Biologies, Elsevier, In press
Comptes Rendus Biologies, Elsevier, In press
Most bacterial ribonucleases (RNases) known to date have been identified in either Escherichia coli or Bacillus subtilis. These two organisms lie on opposite poles of the phylogenetic spectrum, separated by 1-3 billion years of evolution. As a result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a41a5614a4510e9ac393aaef896084
https://hal.archives-ouvertes.fr/hal-03405514/document
https://hal.archives-ouvertes.fr/hal-03405514/document
Autor:
Anastasia Tolcan, Laetitia Gilet, Olivier Pellegrini, Sylvain Durand, Aude Trinquier, Frédérique Braun, Delphine Allouche, Ciarán Condon
Publikováno v:
Methods in Molecular Biology ISBN: 9781071609347
Ribonucleases remodel RNAs to render them functional or to send them on their way toward degradation. In our laboratory, we study these pathways in detail using a plethora of different techniques. These can range from the isolation of RNAs in various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ac4b301b986941b3ea8a4bdfe69c48d
https://doi.org/10.1007/978-1-0716-0935-4_24
https://doi.org/10.1007/978-1-0716-0935-4_24