Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Frédérique, René"'
Autor:
Júlia Canet-Pons, Nesli-Ece Sen, Aleksandar Arsović, Luis-Enrique Almaguer-Mederos, Melanie V. Halbach, Jana Key, Claudia Döring, Anja Kerksiek, Gina Picchiarelli, Raphaelle Cassel, Frédérique René, Stéphane Dieterlé, Nina V. Fuchs, Renate König, Luc Dupuis, Dieter Lütjohann, Suzana Gispert, Georg Auburger
Publikováno v:
Neurobiology of Disease, Vol 152, Iss , Pp 105289- (2021)
Large polyglutamine expansions in Ataxin-2 (ATXN2) cause multi-system nervous atrophy in Spinocerebellar Ataxia type 2 (SCA2). Intermediate size expansions carry a risk for selective motor neuron degeneration, known as Amyotrophic Lateral Sclerosis (
Externí odkaz:
https://doaj.org/article/52a024677ac64e5d9a2e23fc61696b54
Autor:
Robin Waegaert, Sylvie Dirrig-Grosch, Haoyi Liu, Marion Boutry, Ping Luan, Jean-Philippe Loeffler, Frédérique René
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 497 (2022)
CHMP2B is a protein that coordinates membrane scission events as a core component of the ESCRT machinery. Mutations in CHMP2B are an uncommon cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two neurodegenerative diseas
Externí odkaz:
https://doaj.org/article/70e714f51bd5447c8cc1653382503178
Autor:
Robin Waegaert, Sylvie Dirrig-Grosch, Florian Parisot, Céline Keime, Alexandre Henriques, Jean-Philippe Loeffler, Frédérique René
Publikováno v:
Neurobiology of Disease, Vol 136, Iss , Pp 104710- (2020)
Amyotrophic lateral sclerosis and frontotemporal dementia are two neurodegenerative diseases with currently no cure. These two diseases share a clinical continuum with overlapping genetic causes. Mutations in the CHMP2B gene are found in patients wit
Externí odkaz:
https://doaj.org/article/889466d7b8d340a2a6458e0cb99c65fb
Autor:
Cyril Quessada, Alexandra Bouscary, Frédérique René, Cristiana Valle, Alberto Ferri, Shyuan T. Ngo, Jean-Philippe Loeffler
Publikováno v:
Cells, Vol 10, Iss 6, p 1449 (2021)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive and selective loss of motor neurons, amyotrophy and skeletal muscle paralysis usually leading to death due to respiratory failure. While generally c
Externí odkaz:
https://doaj.org/article/1ff75d87f09b464fb571e9ffe82233a0
Autor:
Lavinia Palamiuc, Anna Schlagowski, Shyuan T Ngo, Aurelia Vernay, Sylvie Dirrig‐Grosch, Alexandre Henriques, Anne‐Laurence Boutillier, Joffrey Zoll, Andoni Echaniz‐Laguna, Jean‐Philippe Loeffler, Frédérique René
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 5, Pp 526-546 (2015)
Abstract Amyotrophic lateral sclerosis (ALS) is the most common fatal motor neuron disease in adults. Numerous studies indicate that ALS is a systemic disease that affects whole body physiology and metabolic homeostasis. Using a mouse model of the di
Externí odkaz:
https://doaj.org/article/41d9b19abb1b404ca75e031658be746d
Autor:
Judith Eschbach, Jérôme Sinniger, Jamal Bouitbir, Anissa Fergani, Anna-Isabel Schlagowski, Joffrey Zoll, Bernard Geny, Frédérique René, Yves Larmet, Vincent Marion, Robert H. Baloh, Matthew B. Harms, Michael E. Shy, Nadia Messadeq, Patrick Weydt, Jean-Philippe Loeffler, Albert C. Ludolph, Luc Dupuis
Publikováno v:
Neurobiology of Disease, Vol 58, Iss , Pp 220-230 (2013)
Mutations in the DYNC1H1 gene encoding for dynein heavy chain cause two closely related human motor neuropathies, dominant spinal muscular atrophy with lower extremity predominance (SMA–LED) and axonal Charcot–Marie–Tooth (CMT) disease, and lea
Externí odkaz:
https://doaj.org/article/7d3226828a914e8f87d56033c9cb35bf
Autor:
Michela Gloriani, Luisa Pieroni, Cristiana Valle, Cyril Quessada, Silvia Scaricamazza, Elisabetta Ferraro, Giacomo Giacovazzo, Gabriella Dobrowolny, Hao Wang, Valentina Nesci, Antonio Musarò, Niccolò Candelise, Cinzia Volonté, Illari Salvatori, Shyuan T. Ngo, Jean-Philippe Loeffler, Alberto Ferri, Frédérique René, Tesfaye Wolde Tefera, Susanna Amadio, Aniello Primiano, Andrea Urbani, Elisa Lepore, Alessio Torcinaro, Frederik J. Steyn, Roberto Coccurello
Publikováno v:
British journal of pharmacology 179 (2022): 1732–1752. doi:10.1111/bph.15738
info:cnr-pdr/source/autori:Silvia Scaricamazza, Illari Salvatori, Susanna Amadio, Valentina Nesci, Alessio Torcinaro, Giacomo Giacovazzo, Aniello Primiano, Michela Gloriani, Niccolò Candelise, Luisa Pieroni, Jean-Philippe Loeffler, Frederique Renè, Cyril Quessada, Tesfaye W Tefera, Hao Wang, Frederik J Steyn, Shyuan T Ngo, Gabriella Dobrowolny, Elisa Lepore, Andrea Urbani, Antonio Musarò, Cinzia Volonté, Elisabetta Ferraro, Roberto Coccurello, Cristiana Valle, Alberto Ferri/titolo:Repurposing of Trimetazidine for Amyotrophic Lateral Sclerosis: a study in SOD1 G93A mice/doi:10.1111%2Fbph.15738/rivista:British journal of pharmacology/anno:2022/pagina_da:1732/pagina_a:1752/intervallo_pagine:1732–1752/volume:179
info:cnr-pdr/source/autori:Silvia Scaricamazza, Illari Salvatori, Susanna Amadio, Valentina Nesci, Alessio Torcinaro, Giacomo Giacovazzo, Aniello Primiano, Michela Gloriani, Niccolò Candelise, Luisa Pieroni, Jean-Philippe Loeffler, Frederique Renè, Cyril Quessada, Tesfaye W Tefera, Hao Wang, Frederik J Steyn, Shyuan T Ngo, Gabriella Dobrowolny, Elisa Lepore, Andrea Urbani, Antonio Musarò, Cinzia Volonté, Elisabetta Ferraro, Roberto Coccurello, Cristiana Valle, Alberto Ferri/titolo:Repurposing of Trimetazidine for Amyotrophic Lateral Sclerosis: a study in SOD1 G93A mice/doi:10.1111%2Fbph.15738/rivista:British journal of pharmacology/anno:2022/pagina_da:1732/pagina_a:1752/intervallo_pagine:1732–1752/volume:179
Background and purpose: Amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by the degeneration of upper and lower motor neurons, progressive wasting and paralysis of voluntary muscles is currently incurable despite intense
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8a38f2d23b43968f6a89d83159402a
Autor:
Robin, Waegaert, Sylvie, Dirrig-Grosch, Haoyi, Liu, Marion, Boutry, Ping, Luan, Jean-Philippe, Loeffler, Frédérique, René
Publikováno v:
Biomolecules. 12(4)
CHMP2B is a protein that coordinates membrane scission events as a core component of the ESCRT machinery. Mutations in CHMP2B are an uncommon cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two neurodegenerative diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d568f78163d9b2a90ae89dcfc92eadc
https://pubmed.ncbi.nlm.nih.gov/35454086
https://pubmed.ncbi.nlm.nih.gov/35454086
Autor:
Anissa Fergani, Hugues Oudart, Jose-Luis Gonzalez De Aguilar, Bastien Fricker, Frédérique René, Jean-François Hocquette, Vincent Meininger, Luc Dupuis, Jean-Philippe Loeffler
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 7, Pp 1571-1580 (2007)
Amyotrophic lateral sclerosis (ALS) is the most common adult motor neuron disease, causing motor neuron degeneration, muscle atrophy, paralysis, and death. Despite this degenerative process, a stable hypermetabolic state has been observed in a large
Externí odkaz:
https://doaj.org/article/5d8e59cc20d24c319fb6b046d2d78211
Autor:
Frédérique René, Alberto Ferri, Cristiana Valle, Cyril Quessada, Jean Philippe Loeffler, Shyuan T. Ngo, Alexandra Bouscary
Publikováno v:
Cells
Cells, MDPI, 2021, 10 (6), pp.1449. ⟨10.3390/cells10061449⟩
Cells 10 (2021). doi:10.3390/cells10061449
info:cnr-pdr/source/autori:Quessada C.; Bouscary A.; Rene F.; Valle C.; Ferri A.; Ngo S.T.; Loeffler J.-P./titolo:Skeletal muscle metabolism: Origin or prognostic factor for amyotrophic lateral sclerosis (als) development?/doi:10.3390%2Fcells10061449/rivista:Cells/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Cells, Vol 10, Iss 1449, p 1449 (2021)
Cells, 2021, 10 (6), pp.1449. ⟨10.3390/cells10061449⟩
Cells, MDPI, 2021, 10 (6), pp.1449. ⟨10.3390/cells10061449⟩
Cells 10 (2021). doi:10.3390/cells10061449
info:cnr-pdr/source/autori:Quessada C.; Bouscary A.; Rene F.; Valle C.; Ferri A.; Ngo S.T.; Loeffler J.-P./titolo:Skeletal muscle metabolism: Origin or prognostic factor for amyotrophic lateral sclerosis (als) development?/doi:10.3390%2Fcells10061449/rivista:Cells/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Cells, Vol 10, Iss 1449, p 1449 (2021)
Cells, 2021, 10 (6), pp.1449. ⟨10.3390/cells10061449⟩
International audience; Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive and selective loss of motor neurons, amyotrophy and skeletal muscle paralysis usually leading to death due to respiratory fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8313c852549dd0b4b3baa05c2ac28ae9
https://www.hal.inserm.fr/inserm-03376344/document
https://www.hal.inserm.fr/inserm-03376344/document