Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Frédéric van den Brûle"'
Autor:
Frédéric van den Brûle, Christine Gilles, Jean-Michel Foidart, Carlos López-Otín, Silvia Blacher, Caroline J. Pennington, Vincent Chabottaux, Nor Eddine Sounni, William R. English, Carine Munaut, Dylan R. Edwards, Gillian Murphy, Erik Maquoi, Agnès Noël
Publikováno v:
Cancer Research. 66:5165-5172
Membrane-type matrix metalloproteinases (MT-MMP) constitute a subfamily of six distinct membrane-associated MMPs. Although the contribution of MT1-MMP during different steps of cancer progression has been well documented, the significance of other MT
Autor:
Stéphane Germain, Jean-Michel Foidart, Frédéric van den Brûle, Pierre Corvol, Catherine Monnot, Agnès Noël, Marianne Gervais, Annie Michaud, Xavier Houard
Publikováno v:
International Journal of Cancer. 116:378-384
Like most extracellular matrix (ECM) components, fibronectin (Fn) is proteolyzed generating specific activities. Fibronectin proteinase (Fn-proteinase) represents such a cryptic activity located in the gelatin-binding domain (GBD) of Fn and displays
Autor:
Frédérique Garnier, Vincenzo Castronovo, Stéphane Califice, Frédéric van den Brûle, Pedro L. Fernández, Andrew Berchuck
Publikováno v:
Laboratory Investigation. 83:377-386
Galectin-1 (gal-1) is a 14-kDa laminin-binding galectin involved in several biologic events including regulation of cancer cell proliferation and adhesion to the matrix. In this study, we examined gal-1 expression in 30 human epithelial ovary carcino
Publikováno v:
The Journal of Pathology. 193:80-87
Galectin-1, a member of the beta-galactoside-binding galectin family, is a pleiotropic dimeric protein participating in a variety of normal and pathological processes, including cancer progression. Modulation of the interactions with the basement mem
Publikováno v:
International Journal of Cancer. 89:361-367
Galectin-3, a member of the beta-galactoside-binding lectin family, is involved in a variety of biological events including interactions with galactose-containing glycoconjugates, cell proliferation, differentiation and apoptosis. Galectin-3 appears
Autor:
Pascale Hubert, Sandra L. Giannini, Elizabeth Franzen-Detrooz, Philippe Delvenne, Jacques Boniver, Frédéric van den Brûle
Publikováno v:
The American Journal of Pathology. 154:775-784
The purpose of this study was to investigate the ability of CD1a+ Langerhans/dendritic cells (LCs/DCs) to infiltrate human papillomavirus (HPV)-associated (pre)neoplastic lesions of the uterine cervix. Migration of LCs/DCs in the presence of keratino
Autor:
David Waltregny, Frédéric van den Brûle, Vincenzo Castronovo, Nathalie Clausse, Frédérique Garnier
Publikováno v:
Angiogenesis. 3:317-325
Besides providing tumors with nutrients, newly formed capillaries constitute a potential escape route for tumor cells favoring metastatic dissemination, and constitute an access for the anti-tumoral host immune cells. Galectin-1, a soluble human lect
Autor:
Sylvie Ménard, Alessandra Magnifico, Mark E. Sobel, C. Ghirelli, Frédéric van den Brûle, Vincent Castronovo, Elena Ardini, Elda Tagliabue, Simona Butò, Maria I. Colnaghi
Publikováno v:
Journal of Cellular Biochemistry. 69:244-251
Even though the involvement of the 67-kDa laminin receptor (67LR) in tumor invasiveness has been clearly demonstrated, its molecular structure remains an open problem, since only a full-length gene encoding a 37-kDa precursor protein (37LRP) has been
Autor:
Frédéric van den Brûle, René Lambotte, Crina Buicu, Pedro L. Fernández, Pascale Jackers, Fu-Tong Liu, Vincent Castronovo
Publikováno v:
Developmental Dynamics. 209:399-405
Development of complex organisms requires specific temporospatial differentiation and expression of the correct phenotype through activation of a variety of genes. Galectins are mammalian lectins able to interact with various extracellular matrix gly
Autor:
Frédéric van den Brûle, Manuel Deprez, Douglas N.W. Cooper, Mark E. Sobel, Crina Buicu, Vincent Castronovo, Robert C. Bast, Claudette Pieters, Andrew Berchuck, Fu-Tong Liu
Publikováno v:
Human Pathology. 27:1185-1191
Alterations of tumor cell interactions with laminin, a basement membrane glycoprotein, are consistent features of the invasive and metastatic phenotype. Qualitative and quantitative changes in the expression of cell surface laminin-binding proteins h