Výsledky vyhledávání - "Frédéric Vigant"

Akademický článek

Hexon modification to improve the activity of oncolytic adenovirus vectors against neoplastic and stromal cells in pancreatic cancer.

Autor: Tanja Lucas, Karim Benihoud, Frédéric Vigant, Christoph Q Schmidt, Andreas Wortmann, Max G Bachem, Thomas Simmet, Stefan Kochanek

Publikováno v: PLoS ONE, Vol 10, Iss 2, p e0117254 (2015)

Primary pancreatic carcinoma has an unfavourable prognosis and standard treatment strategies mostly fail in advanced cases. Virotherapy might overcome this resistance to current treatment modalities. However, data from clinical studies with oncolytic

Externí odkaz: https://doaj.org/article/39e263ab526245c381a503ad613e2e16

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Supplementary Table 2 from Intratumoral Induction of CD103 Triggers Tumor-Specific CTL Function and CCR5-Dependent T-Cell Retention

Autor: Fathia Mami-Chouaib, Christophe Combadière, Salem Chouaib, Pierre Validire, Karim Benihoud, Andrzej Mackiewicz, Isabelle Vergnon, Thomas Robert, Frédéric Vigant, Abdelali Jalil, Audrey Le Floc'h, Katarzyna Franciszkiewicz

Supplementary Table 2 from Intratumoral Induction of CD103 Triggers Tumor-Specific CTL Function and CCR5-Dependent T-Cell Retention

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2317aece4a15382502025b940d16747c
https://doi.org/10.1158/0008-5472.22378835

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Data from Intratumoral Induction of CD103 Triggers Tumor-Specific CTL Function and CCR5-Dependent T-Cell Retention

We have reported previously that the interaction of αE(CD103)β7 integrin, expressed on a CD8+ tumor-infiltrating lymphocyte (TIL) clone but not on a peripheral blood lymphocyte (PBL) counterpart, with the epithelial marker E-cadherin on human lung

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d06f6bd654a7105173f52f43c6c061c
https://doi.org/10.1158/0008-5472.c.6499028.v1

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Supplementary Figure 1 from Intratumoral Induction of CD103 Triggers Tumor-Specific CTL Function and CCR5-Dependent T-Cell Retention

Supplementary Figure 1 from Intratumoral Induction of CD103 Triggers Tumor-Specific CTL Function and CCR5-Dependent T-Cell Retention

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf833b8b145f57ee0252953a9c1bd94
https://doi.org/10.1158/0008-5472.22378844.v1

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Supplementary Figure 2 from Intratumoral Induction of CD103 Triggers Tumor-Specific CTL Function and CCR5-Dependent T-Cell Retention

Supplementary Figure 2 from Intratumoral Induction of CD103 Triggers Tumor-Specific CTL Function and CCR5-Dependent T-Cell Retention

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3015a9d255635d3bd98984e470f120af
https://doi.org/10.1158/0008-5472.22378841.v1

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Supplementary Table 1 from Intratumoral Induction of CD103 Triggers Tumor-Specific CTL Function and CCR5-Dependent T-Cell Retention

Supplementary Table 1 from Intratumoral Induction of CD103 Triggers Tumor-Specific CTL Function and CCR5-Dependent T-Cell Retention

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0767ee78c943d200f12e5ebd3cdd458c
https://doi.org/10.1158/0008-5472.22378838

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Pseudotyping Serotype 5 Adenovirus with the Fiber from Other Serotypes Uncovers a Key Role of the Fiber Protein in Adenovirus 5-Induced Thrombocytopenia

Autor: Frédéric Vigant, Najat Raddi, Karim Benihoud, Stéphane Giraudier, Oriane Wagner-Ballon, Silvio Hemmi, Jerome Custers

Publikováno v: Human Gene Therapy. 27:193-201

Adenovirus (Ad) infection in humans is associated with inflammatory responses and thrombocytopenia. Although several studies were conducted in mice models to understand molecular and cellular mechanisms of Ad-induced inflammatory responses, only few

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2eb9e9079a9d0247429d264c4785d87
https://doi.org/10.1089/hum.2015.154

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Intratumoral Induction of CD103 Triggers Tumor-Specific CTL Function and CCR5-Dependent T-Cell Retention

Autor: Christophe Combadière, Thomas Robert, Abdelali Jalil, Audrey Le Floc’h, Katarzyna Franciszkiewicz, Pierre Validire, Andrzej Mackiewicz, Isabelle Vergnon, Karim Benihoud, Salem Chouaib, Fathia Mami-Chouaib, Frédéric Vigant

Publikováno v: Cancer Research. 69:6249-6255

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4fc9e9e6f3bd5d46ebd7be59451888
https://doi.org/10.1158/0008-5472.can-08-3571

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Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid

Autor: Ronan Chaligne, Stéphane Giraudier, E. Muth, Michel Perricaudet, Céline Bouquet, Karim Benihoud, Frédéric Vigant, Betsy Jullienne

Publikováno v: Gene Ther
Gene Ther, 2009, epub ahead of print. ⟨10.1038/gt.2009.97⟩

International audience; Adenovirus (Ad)-mediated delivery of anti-angiogenic molecules into tumors constitutes an appealing approach for growth inhibition. However, lack of expression on tumors of Ad receptors leads to weak tumor transduction. Theref

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6681f09c16597ca80302605587526c1
https://hal.archives-ouvertes.fr/hal-00431360

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Substitution of hexon hypervariable region 5 of adenovirus serotype 5 abrogates blood factor binding and limits gene transfer to liver

Autor: Frédéric Vigant, Betsy Jullienne, Paule Opolon, Stéphanie Esselin, Karim Benihoud, Emmanuelle Vigne, Michel Perricaudet, Thierry Tordjmann, Elisabeth Connault, Delphyne Descamps

Publikováno v: Molecular Therapy
Molecular Therapy, 2008, 16 (8), pp.1474-80. ⟨10.1038/mt.2008.132⟩
Molecular Therapy, Cell Press, 2008, 16 (8), pp.1474-80. ⟨10.1038/mt.2008.132⟩
Molecular Therapy 8 (16), 1474-80. (2008)

Liver tropism potentially leading to massive hepatocyte transduction and hepatotoxicity still represents a major drawback to adenovirus (Ad)-based gene therapy. We previously demonstrated that substitution of the hexon hypervariable region 5 (HVR5),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5031f121bc8db649ef4628eab0d0c1f
https://hal.science/hal-00315859

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