Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Frédéric Van Gool"'
Autor:
Hind Hussein, Sébastien Denanglaire, Frédéric Van Gool, Abdulkader Azouz, Yousra Ajouaou, Hana El-Khatib, Guillaume Oldenhove, Oberdan Leo, Fabienne Andris
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
RORγt-expressing Tregs form a specialized subset of intestinal CD4+ Foxp3+ cells which is essential to maintain gut homeostasis and tolerance to commensal microbiota. Recently, c-Maf emerged as a critical factor in the regulation of RORγt expressio
Externí odkaz:
https://doaj.org/article/5b6f4b76b978471a84b84521bf3b3619
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0217728 (2019)
Regulatory T cells (Tregs) are an immunosuppressive population that are identified based on the stable expression of the fate-determining transcription factor forkhead box P3 (Foxp3). Tregs can be divided into distinct subsets based on whether they d
Externí odkaz:
https://doaj.org/article/523031b6ab2d4d76bedf4d8c8c01d313
Autor:
Benjamin Bondue, Olivier Vosters, Patricia de Nadai, Stéphanie Glineur, Olivier De Henau, Souphalone Luangsay, Frédéric Van Gool, David Communi, Paul De Vuyst, Daniel Desmecht, Marc Parmentier
Publikováno v:
PLoS Pathogens, Vol 7, Iss 11, p e1002358 (2011)
Viral diseases of the respiratory tract, which include influenza pandemic, children acute bronchiolitis, and viral pneumonia of the elderly, represent major health problems. Plasmacytoid dendritic cells play an important role in anti-viral immunity,
Externí odkaz:
https://doaj.org/article/a3b2689ce35844febb0ab1d8bc628207
Autor:
Nathalie Busso, Mahir Karababa, Massimo Nobile, Aline Rolaz, Frédéric Van Gool, Mara Galli, Oberdan Leo, Alexander So, Thibaut De Smedt
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2267 (2008)
Nicotinamide phosphoribosyltransferase (NAMPT), also known as visfatin, is the rate-limiting enzyme in the salvage pathway of NAD biosynthesis from nicotinamide. Since its expression is upregulated during inflammation, NAMPT represents a novel clinic
Externí odkaz:
https://doaj.org/article/47341f4c91b14572a6d75de2584587a5
Autor:
Roxxana Valeria Beltran Valencia, Alexander Marson, Frédéric Van Gool, Patrick Ho, Justin Eyquem, Theodore L. Roth, Jeffrey A. Bluestone, James A. Wells, Caroline Raffin, Qizhi Tang, Duy P. Nguyen, Leonardo M. R. Ferreira, Zion Congrave-Wilson, Yannick D. Muller
Anti-CD19 chimeric antigen receptor (CD19-CAR)-engineered T cells are approved therapeutics for malignancies. The impact of the hinge (HD) and transmembrane (TMD) domains between the extracellular antigen-targeting and the intracellular signaling mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bbb4d87b70c6585fe9002a153d70427
https://doi.org/10.1101/2020.09.18.296913
https://doi.org/10.1101/2020.09.18.296913
Autor:
Bin Zhang, Ian A. Vogel, Zhaolin Sun, Eric Shifrut, Siqi Chen, Igal Ifergan, Grace Y. Prator, Yana Zhang, Youjin V. Lee, Oren Shaked, Frédéric Van Gool, Zhongmei Li, Jessica T. Cortez, Yuanming Xu, Jeffrey A. Bluestone, Dimitre R. Simeonov, Theodore L. Roth, Elena Montauti, Deyu Fang, Y Zhang, Alexander Marson
Regulatory T cells (Tregs) are required to control immune responses and maintain homeostasis but are a significant barrier to anti-tumor immunity1. Conversely, Treg instability, characterized by loss of the master transcription factor Foxp3 and acqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852ebc7166052cd61655467b8118b2f5
Autor:
Youjin V. Lee, Siqi Chen, Zhongmei Li, Eric Shifrut, Dimitre R. Simeonov, Igal Ifergan, Diana C. Hargreaves, Jonathan M. Woo, Jessica T. Cortez, Y Zhang, Alexander Marson, Oren Shaked, Ian A. Vogel, Jeffrey A. Bluestone, Zhaolin Sun, Yuanming Xu, Theodore L. Roth, Frédéric Van Gool, Elena Montauti, Deyu Fang, Josephine Ho, Grace Y. Prator, Jovylyn Gatchalian, Yana Zhang, Bin Zhang
Publikováno v:
Nature
Regulatory T (Treg) cells are required to control immune responses and maintain homeostasis, but are a significant barrier to antitumour immunity1. Conversely, Treg instability, characterized by loss of the master transcription factor Foxp3 and acqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ea7eb08b62650018583c58c62c2ee1
https://pubmed.ncbi.nlm.nih.gov/32499641
https://pubmed.ncbi.nlm.nih.gov/32499641
Autor:
Stephan Ehl, Olle Kämpe, Olov Ekwall, Outi Mäkitie, Eystein S. Husebye, Anders Rönnblom, Sophie Bensing, Federica Barzaghi, Nils Landegren, Fabian Sardh, Hörður Ingi Gunnarsson, Rosa Bacchetta, Frédéric Van Gool, Saila Laakso, Åsa Hallgren, Mark S. Anderson, Christina Lundqvist, Alice Y. Chan, Daniel Eriksson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbdd5369fdcbe29962dc14eda897bfec
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-390434
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-390434
Autor:
Maxwell R. Mumbach, Nicki Naddaf, Theodore L. Roth, Nicolas Bray, Ruize Liu, Chun Jimmie Ye, K. Mark Ansel, Graham J. Ray, Mark S. Anderson, Dmytro Lituiev, Benjamin G. Gowen, Zhongmei Li, Therese Mitros, John D. Gagnon, Kyle Kai-How Farh, Hong Ma, Jacob E. Corn, Eric Boyer, Hailiang Huang, Youjin Lee, William J. Greenleaf, Rachel E. Gate, Victoria Tobin, Julia S. Chu, Meena Subramaniam, Ansuman T. Satpathy, Kathrin Schumann, Gemma L. Curie, Alexander Marson, Alice Y. Chan, Jonathan M. Woo, Mandy Boontanrart, Mark J. Daly, Michelle L.T. Nguyen, Frédéric Van Gool, Dimitre R. Simeonov, Howard Y. Chang, Jeffrey A. Bluestone
Publikováno v:
Nature. 559(7715)
The majority of genetic variants associated with common human diseases map to enhancers, non-coding elements that shape cell-type-specific transcriptional programs and responses to extracellular cues1–3. Systematic mapping of functional enhancers a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daab57aa610b3723cc39edf7c3e3365b
https://pubmed.ncbi.nlm.nih.gov/28854172
https://pubmed.ncbi.nlm.nih.gov/28854172
Autor:
Ajit Shah, Frédéric Van Gool, Anil Bhushan, Mark A. Atkinson, Peter Thompson, Vasilis Ntranos
Publikováno v:
Cell metabolism. 29(5)
Type 1 diabetes (T1D) is an organ-specific autoimmune disease characterized by hyperglycemia due to progressive loss of pancreatic beta cells. Immune-mediated beta cell destruction drives the disease, but whether beta cells actively participate in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fab3767d8ff6067f68778ea49f6042b
https://pubmed.ncbi.nlm.nih.gov/30799288
https://pubmed.ncbi.nlm.nih.gov/30799288