Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Frédéric Sedel"'
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background We proposed to investigate high-dose pharmaceutical-grade biotin in a population of demyelinating neuropathies of different aetiologies, as a proof-of-concept. Methods Phase IIb open label, uncontrolled, single center, pilot study
Externí odkaz:
https://doaj.org/article/e367d3a2891a45cebfb9fbefbfc50812
Autor:
Gilbert Zakine, Anne Perruisseau-Carrier, Corinne Becker, Frédéric Sedel, Luc Téot, Denis Barritault
Publikováno v:
Aesthetic Surgery Journal Open Forum, Vol 5 (2023)
Abstract BackgroundCACIPLIQ20 (OTR3, Paris, France) is a medical device used for the treatment of chronic skin ulcers. It contains a heparan sulfate mimetic that accelerates tissue healing by stabilizing matrix proteins and protecting heparin-bindin
Externí odkaz:
https://doaj.org/article/14147e7ca7c74439afc607ad177f20a2
Autor:
Marion J. F. Levy, Beatriz Garcia-Diaz, Frédéric Sedel, Anne Baron-Van Evercooren, Sabah Mozafari
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15733 (2022)
Accumulating evidences suggest a strong correlation between metabolic changes and neurodegeneration in CNS demyelinating diseases such as multiple sclerosis (MS). Biotin, an essential cofactor for five carboxylases, is expressed by oligodendrocytes a
Externí odkaz:
https://doaj.org/article/e774ea7b67144dd4a0678dc4fc841c3c
Autor:
Raul Juntas-Morales, Nicolas Pageot, Abdelkarim Bendarraz, Sébastien Alphandéry, Frédéric Sedel, Stéphanie Seigle, William Camu
Publikováno v:
EClinicalMedicine, Vol 19, Iss , Pp - (2020)
Background: Oligodendrocytes (OGs) provide metabolic support to motor neurons (MNs) and are implicated in the pathophysiology of amyotrophic lateral sclerosis (ALS). MD1003, or high-dose Pharmaceutical grade Biotin (hdPB), may improve disability in p
Externí odkaz:
https://doaj.org/article/808df3a8ac1b42b99b763bfd9e5f5b3c
Autor:
Jennifer Graves, Adrian Pace, Maria Pia Sormani, Devon S. Conway, Bianca Weinstock-Guttman, Frederick E. Munschauer, Corey C. Ford, Vernon Rowe, Jana Lizrova Preiningerova, Shiv Saidha, Radek Ampapa, Jens Kuhle, Harold L. Moses, Claire S Riley, Tobias Derfuss, Lilyana Amezcua, Joshua Barton, Kottil Rammohan, Pierre Duquette, Thomas Leist, Alexander Rae-Grant, Evanthia Bernitsas, Myla D. Goldman, R. Talab, Jerry S. Wolinsky, Nina De Klippel, Guillermo Izquierdo Ayuso, Bridget Bagert, Virginia Devonshire, Mariko Kita, Hayrettin Tumani, Bhatia Perminder, Scott D. Newsome, Paul S. Giacomini, Frédéric Sedel, Jan Lycke, M. S. Freedman, Stewart Webb, Sanjay Yathiraj, Agata Klosek, Stephen Krieger, Edward Fox, Malgorzata Zajda, Eva Meluzinova, Valerie J Block, Lluís Ramió-Torrentà, John R. Corboy, Aaron E. Miller, Xavier Montalban, Mark A. Agius, Michelle L Apperson, Patricia K. Coyle, Giancarlo Comi, Jose Enrique Martinez Rodriguez, Daniela Rau, Derrick Robertson, Elias Hamp Birte, Douglas L. Arnold, Fred D. Lublin, Galina Vorobeychik, Benjamin Greenberg, Mathias Buttmann, Daniel Bandari, Ludivine Witkowski, Sharon G. Lynch, Victoria Fernandez Sanchez, Jonathan Calkwood, Maria Satori, Tania Kuempfel, Rana K. Zabad, J. Marc Girard, Bruce A.C. Cree, Ahmed T. Toosy, Don J. Mahad, Bruce A. Cohen, Jozef Koscielniak, Jonathan Carter, Daniel Selchen, Paul Friedemann, Sharon Stoll, Fryze Waldemar, Gerd Reifschneider, Mark S. Freedman, Gary Cutter, Franz Fazekas, Robert T. Naismith, Marta Vachova, Richard MacDonell, Mary Ann Picone, Gavin Giovannoni, Randall Trudell, Barbara Willekens, Orhan Aktas, Mark Marriott, Roger McKelvey, Bruce C.A. Cree, Christopher Severson, Rafael Arroyo Gonzalez, Kyle Smoot, Murat Terzi, Joanna Cooper, Lou Brundin, Hans-Peter Hartung, Piotr Sokolowski, Joe Guadagno, Stephen C. Reingold, Klaus Schmierer, Guy Laureys, Robert P. Lisak, Lawrence Samkoff, Carlo Pozzilli, Celia Oreja Guevara, Mitchel Freedman, Anthony T. Reder
Publikováno v:
The lancet neurology
Background: There is an unmet need to develop therapeutic interventions directed at the neurodegeneration that underlies progression in multiple sclerosis. High-dose, pharmaceutical-grade biotin (MD1003) might enhance neuronal and oligodendrocyte ene
Autor:
Sebastien Alphandery, Abdelkarim Bendarraz, Frédéric Sedel, William Camu, Raul Juntas-Morales, Nicolas Pageot, Stéphanie Seigle
Publikováno v:
EClinicalMedicine
EClinicalMedicine, Elsevier, 2020, 19, pp.100254. ⟨10.1016/j.eclinm.2019.100254⟩
EClinicalMedicine, Vol 19, Iss, Pp-(2020)
EClinicalMedicine, Elsevier, 2020, 19, pp.100254. ⟨10.1016/j.eclinm.2019.100254⟩
EClinicalMedicine, Vol 19, Iss, Pp-(2020)
Background: Oligodendrocytes (OGs) provide metabolic support to motor neurons (MNs) and are implicated in the pathophysiology of amyotrophic lateral sclerosis (ALS). MD1003, or high-dose Pharmaceutical grade Biotin (hdPB), may improve disability in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e03419b1ada91da2bf2008d49b6d92
https://hal.archives-ouvertes.fr/hal-03467286
https://hal.archives-ouvertes.fr/hal-03467286
Autor:
Montserrat Ruiz, Agatha Schlüter, Janani Parameswaran, Benoit Colsch, Frédéric Sedel, Isidre Ferrer, Aurora Pujol, Leire Goicoechea, M. Flint Beal, Nathalie Launay, Stéphane Fourcade, Noel Y. Calingasan, Alexandre Seyer
Publikováno v:
Brain Pathology
Brain Pathology, 2020, 30 (5), pp.945-963. ⟨10.1111/bpa.12869⟩
Brain Pathology, Wiley, 2020, 30 (5), pp.945-963. ⟨10.1111/bpa.12869⟩
Brain Pathol
Brain Pathology, 2020, 30 (5), pp.945-963. ⟨10.1111/bpa.12869⟩
Brain Pathology, Wiley, 2020, 30 (5), pp.945-963. ⟨10.1111/bpa.12869⟩
Brain Pathol
International audience; Biotin is an essential cofactor for carboxylases that regulates the energy metabolism. Recently, high-dose pharmaceutical-grade biotin (MD1003) was shown to improve clinical parameters in a subset of patients with chronic prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6b07c9cb152ea4bbcbe6e485c4941d
https://hal.inrae.fr/hal-03349346
https://hal.inrae.fr/hal-03349346
Autor:
Marie-Liesse Piketty, Claude Hercend, Jean-Claude Souberbielle, Delphine Bernard, Dominique Prié, Philippe Chanson, Frédéric Sedel
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 55:817-825
Background: High-dose biotin therapy is beneficial in progressive multiple sclerosis (MS) and is expected to be adopted by a large number of patients. Biotin therapy leads to analytical interference in many immunoassays that utilize streptavidin-biot
Autor:
Marika Rudler, Nicolas Weiss, Dominique Thabut, Foucauld Isnard, Maria del Mar Amador, Foudil Lamari, Frédéric Sedel, Suleiman Attala, Christophe Junot, Pierre Barbier Saint Hilaire, Benoit Colsch, Augustin Schaefer
Publikováno v:
Journal of Hepatology. 65:1120-1130
Background & Aims Hepatic encephalopathy (HE) is a neurological complication observed in patients with liver disease and/or porto-systemic shunt. The proportion of cirrhotic patients developing overt HE is about 20%, and 60–80% of cirrhotic patient
Autor:
Marika Rudler, Charlotte Bouzbib, Augustin Schaefer, Benoit Colsch, Pierre Barbier Saint Hilaire, Christophe Junot, Nicolas Weiss, Frédéric Sedel, Dominique Thabut, Foudil Lamari, Suleiman Attala
Publikováno v:
American Journal of Gastroenterology. 114:S32-S33