Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Frédéric Saltel"'
Autor:
Sara Basbous, Lydia Dif, Camille Dantzer, Sylvaine Di-Tommaso, Jean-William Dupuy, Paulette Bioulac-Sage, Anne-Aurélie Raymond, Chantal Desdouets, Frédéric Saltel, Violaine Moreau
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Entosis is a process that leads to the formation of cell-in-cell structures commonly found in cancers. Here, we identified entosis in hepatocellular carcinoma and the loss of Rnd3 (also known as RhoE) as an efficient inducer of this mechanis
Externí odkaz:
https://doaj.org/article/00a999658bed44e197ffd3d054843606
Autor:
Sylvaine Di Tommaso, Cyril Dourthe, Jean-William Dupuy, Nathalie Dugot-Senant, David Cappellen, Hélène Cazier, Valérie Paradis, Jean-Frédéric Blanc, Brigitte Le Bail, Charles Balabaud, Paulette Bioulac-Sage, Frédéric Saltel, Anne-Aurélie Raymond
Publikováno v:
JHEP Reports, Vol 6, Iss 2, Pp 100913- (2024)
Background & Aims: Hepatocellular adenomas (HCAs) are rare, benign, liver tumours classified at the clinicopathological, genetic, and proteomic levels. The β-catenin-activated (b-HCA) subtypes harbour several mutation types in the β-catenin gene (C
Externí odkaz:
https://doaj.org/article/88ae01c559c44a39946de35c754a7779
Autor:
Bertrand Chauveau, Antoine Garric, Sylvaine Di Tommaso, Anne-Aurélie Raymond, Jonathan Visentin, Agathe Vermorel, Nathalie Dugot-Senant, Julie Déchanet-Merville, Jean-Paul Duong Van Huyen, Marion Rabant, Lionel Couzi, Frédéric Saltel, Pierre Merville
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Antibody-mediated rejection (ABMR) is the leading cause of allograft failure in kidney transplantation. Defined by the Banff classification, its gold standard diagnosis remains a challenge, with limited inter-observer reproducibility of the
Externí odkaz:
https://doaj.org/article/3388bc24064846ebb66e5222bec96961
Autor:
Caroline Gest, Sandra Sena, Lydia Dif, Véronique Neaud, Robin Loesch, Nathalie Dugot-Senant, Lisa Paysan, Léo Piquet, Terezinha Robbe, Nathalie Allain, Doulaye Dembele, Catherine Guettier, Paulette Bioulac-Sage, Anne Rullier, Brigitte Le Bail, Christophe F. Grosset, Frédéric Saltel, Valérie Lagrée, Sabine Colnot, Violaine Moreau
Publikováno v:
JHEP Reports, Vol 5, Iss 5, Pp 100691- (2023)
Background & Aims: β-catenin is a well-known effector of the Wnt pathway, and a key player in cadherin-mediated cell adhesion. Oncogenic mutations of β-catenin are very frequent in paediatric liver primary tumours. Those mutations are mostly hetero
Externí odkaz:
https://doaj.org/article/842490d9fd564a5d9087b3a228132176
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Type I collagen, the major components of breast interstitial stroma, is able to regulate breast carcinoma cell behavior. Discoidin domain receptor 1 (DDR1) is a type I collagen receptor playing a key role in this process. In fact, collagen/DDR1 axis
Externí odkaz:
https://doaj.org/article/f0fa8acde1f741b58429178db5e6fcf9
Autor:
Margaux Sala, Delphine Gonzales, Thierry Leste‐Lasserre, Nathalie Dugot‐Senant, Valérie Paradis, Sylvaine Di Tommaso, Jean‐William Dupuy, Vincent Pitard, Cyril Dourthe, Amedeo Sciarra, Christine Sempoux, Linda D. Ferrell, Andrew D. Clouston, Gregory Miller, Mathew M. Yeh, Swan Thung, Annette S.H. Gouw, Alberto Quaglia, Jing Han, Ji Huan, Cathy Fan, James Crawford, Yasuni Nakanuma, Kenichi Harada, Brigitte leBail, Claire Castain, Nora Frulio, Hervé Trillaud, Laurent Possenti, Jean‐Frédéric Blanc, Laurence Chiche, Christophe Laurent, Charles Balabaud, Paulette Bioulac‐Sage, Anne Aurélie Raymond, Frédéric Saltel
Publikováno v:
Hepatology Communications, Vol 4, Iss 6, Pp 809-824 (2020)
Until recently, 10% of hepatocellular adenomas (HCAs) remained unclassified (UHCA). Among the UHCAs, the sonic hedgehog HCA (shHCA) was defined by focal deletions that fuse the promoter of Inhibin beta E chain with GLI1. Prostaglandin D2 synthase was
Externí odkaz:
https://doaj.org/article/a964102491fb4c51a8bbff73d7a74e81
Autor:
Esra Karatas, Anne-Aurélie Raymond, Céline Leon, Jean-William Dupuy, Sylvaine Di-Tommaso, Nathalie Senant, Sophie Collardeau-Frachon, Mathias Ruiz, Alain Lachaux, Frédéric Saltel, Marion Bouchecareilh
Publikováno v:
JHEP Reports, Vol 3, Iss 4, Pp 100297- (2021)
Background & Aims: A single point mutation in the Z-variant of alpha 1-antitrypsin (Z-AAT) alone can lead to both a protein folding and trafficking defect, preventing its exit from the endoplasmic reticulum (ER), and the formation of aggregates that
Externí odkaz:
https://doaj.org/article/cd2a5379a66d4260bbcd81ed38d213f3
Autor:
Bertrand Chauveau, Anne-Aurélie Raymond, Sylvaine Di Tommaso, Jonathan Visentin, Agathe Vermorel, Nathalie Dugot-Senant, Cyril Dourthe, Jean-William Dupuy, Julie Déchanet-Merville, Jean-Paul Duong Van Huyen, Marion Rabant, Lionel Couzi, Frédéric Saltel, Pierre Merville
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 569 (2022)
Antibody-mediated rejection (ABMR) is the leading cause of allograft failure in kidney transplantation. Its histological hallmark is represented by lesions of glomerulitis i.e., inflammatory cells within glomeruli. Current therapies for ABMR fail to
Externí odkaz:
https://doaj.org/article/9a5ca9a691d748268da69b7689dcdeec
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Tumor microenvironment, including extracellular matrix (ECM) and stromal cells, is a key player during tumor development, from initiation, growth and progression to metastasis. During all of these steps, remodeling of matrix components occurs, changi
Externí odkaz:
https://doaj.org/article/3980cd2763b74e58a719bfaacb915ebf
Autor:
Zakaria Ezzoukhry, Elodie Henriet, Fabrice P. Cordelières, Jean-William Dupuy, Marlène Maître, Nathan Gay, Sylvaine Di-Tommaso, Luc Mercier, Jacky G. Goetz, Marion Peter, Frédéric Bard, Violaine Moreau, Anne-Aurélie Raymond, Frédéric Saltel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Invadosomes degrade extracellular matrix and facilitate cell invasion but their molecular composition is not fully understood. Here, the authors combine laser capture and mass spectrometry to map the proteome of invadosomes, showing that they rely on
Externí odkaz:
https://doaj.org/article/2c995818d6d044ceb85f3e411b0ea6e8