Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Frédéric R. Santer"'
Publikováno v:
Nutrients, Vol 15, Iss 10, p 2384 (2023)
Isochromosome 12p (iChr12p) is typical in almost all invasive testicular cancers. Increased copy number of genes on 12p is associated with the development of a clinically manifest tumor; however, the causative genes have not yet been identified. Chro
Externí odkaz:
https://doaj.org/article/e8b39393ab704bdcb5773ae42630305d
Autor:
Gertrud E. Feiersinger, Kristina Trattnig, Peter D. Leitner, Fabian Guggenberger, Alexander Oberhuber, Sarah Peer, Martin Hermann, Ira Skvortsova, Jana Vrbkova, Jan Bouchal, Zoran Culig, Frédéric R. Santer
Publikováno v:
Molecular Oncology, Vol 12, Iss 4, Pp 561-576 (2018)
A number of prostate cancer (PCa)‐specific genomic aberrations (denominated BRCAness genes) have been discovered implicating sensitivity to PARP inhibition within the concept of synthetic lethality. Recent clinical studies show favorable results fo
Externí odkaz:
https://doaj.org/article/d6ce9ba31a4a4172989bdef9eb2f89e3
Autor:
Zoran Culig, Holger H.H. Erb, Frank Claessens, Wytske M. van Weerden, Rute B. Marques, Frédéric R. Santer, Fabian Guggenberger, Martina Gruber, Julia Hoefer, Nicla Lorito, Georg Schaefer, Martin Puhr, Florian Handle
Canonical activation of the AR (by R1881) and of STAT3 (by IL6) are rapid processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b08085bc5ac3499c6ab8401e340cfa4
https://doi.org/10.1158/1535-7163.22504522
https://doi.org/10.1158/1535-7163.22504522
Autor:
Zoran Culig, Frédéric R. Santer, Glen Kristiansen, Walther Parson, Dimo Dietrich, Julia Hoefer, Birgit Luef, Holger H.H. Erb, Florian Handle
Supplementary Fig. S1 Epigenetic regulation of SOCS3 in cell lines. A, SOCS3 mRNA was measured in AR positive prostate cancer cell lines after treatement with 10 mM 5-Aza-2'deoxycytidine for 72 hours. B, publicly available Bisulfite-Seq. data for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71723634754f9ca32a56ba6aabeaece8
https://doi.org/10.1158/1541-7786.22515106.v1
https://doi.org/10.1158/1541-7786.22515106.v1
Autor:
Zoran Culig, Philip A. Cole, David J. Meyers, Walther Parson, Ilaria T. Cavarretta, Jan Bouchal, Holger H.H. Erb, Su Jung Oh, Philipp P.S. Höschele, Frédéric R. Santer
Supplementary Figure 2 from Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5411d7a5ca4c4abceede5d014fcdcfdf
https://doi.org/10.1158/1535-7163.22497157
https://doi.org/10.1158/1535-7163.22497157
Autor:
Zoran Culig, Holger H.H. Erb, Frank Claessens, Wytske M. van Weerden, Rute B. Marques, Frédéric R. Santer, Fabian Guggenberger, Martina Gruber, Julia Hoefer, Nicla Lorito, Georg Schaefer, Martin Puhr, Florian Handle
IL6/STAT3 signaling is associated with endocrine therapy resistance in prostate cancer, but therapies targeting this pathway in prostate cancer were unsuccessful in clinical trials so far. The mechanistic explanation for this phenomenon is currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d1d48a3c096b978cdd814264163248
https://doi.org/10.1158/1535-7163.c.6537760
https://doi.org/10.1158/1535-7163.c.6537760
Autor:
Zoran Culig, Frédéric R. Santer, Glen Kristiansen, Walther Parson, Dimo Dietrich, Julia Hoefer, Birgit Luef, Holger H.H. Erb, Florian Handle
SOCS3 is not regulated on post-transcriptional level by R1881. A luciferase reporter vector containing the coding sequence (CDS) and the 3'UTR of SOCS3 in the untranslated region after the luciferase stop codon was transfected into LNCaP cells. Treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dde517ca0156c9253d7e51711749df8
https://doi.org/10.1158/1541-7786.22515112
https://doi.org/10.1158/1541-7786.22515112
Autor:
Zoran Culig, Philip A. Cole, David J. Meyers, Walther Parson, Ilaria T. Cavarretta, Jan Bouchal, Holger H.H. Erb, Su Jung Oh, Philipp P.S. Höschele, Frédéric R. Santer
Supplementary Figure 4 from Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96afaf7c5fd2b994885c108c55aab2ad
https://doi.org/10.1158/1535-7163.22497151.v1
https://doi.org/10.1158/1535-7163.22497151.v1
Autor:
Zoran Culig, Holger H.H. Erb, Frank Claessens, Wytske M. van Weerden, Rute B. Marques, Frédéric R. Santer, Fabian Guggenberger, Martina Gruber, Julia Hoefer, Nicla Lorito, Georg Schaefer, Martin Puhr, Florian Handle
The GR is expressed in some of the used cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc4a8fe43c086946990ab95a91767dd
https://doi.org/10.1158/1535-7163.22504516
https://doi.org/10.1158/1535-7163.22504516
Autor:
Zoran Culig, Philip A. Cole, David J. Meyers, Walther Parson, Ilaria T. Cavarretta, Jan Bouchal, Holger H.H. Erb, Su Jung Oh, Philipp P.S. Höschele, Frédéric R. Santer
Supplementary Table Legends 1-5 from Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2d78338af7e4f8e256107335e9212f
https://doi.org/10.1158/1535-7163.22497145.v1
https://doi.org/10.1158/1535-7163.22497145.v1