Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Frédéric Peyrane"'
Publikováno v:
Drug Discovery Today. 26:2182-2189
Antimicrobial susceptibility tests (AST) are based on the minimal inhibitory concentration (MIC), the method used worldwide to guide antimicrobial therapy. Despite its relevance in correctly predicting clinical outcome for most acute infections, this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4cb7330e137dd06f527b9007d1771a
https://doi.org/10.1016/j.drudis.2021.05.018
https://doi.org/10.1016/j.drudis.2021.05.018
Publikováno v:
Photochemistry and Photobiology
Photochemistry and Photobiology, Wiley, 2021, ⟨10.1111/php.13541⟩
Photochemistry and Photobiology, Wiley, 2021, ⟨10.1111/php.13541⟩
International audience; The [2 + 2] photocycloaddition of natural pyrimidine nucleobases is devoid of regioselectivity. Although modified pyrimidines have been developed to selectively obtain syn-cyclobutane isomers, the targeted formation of anti-cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8198dbb893bdd6cd8bbe46b722b18da9
https://hal.archives-ouvertes.fr/hal-03429572
https://hal.archives-ouvertes.fr/hal-03429572
Autor:
Ian H. Gilbert, Kenneth Pfarr, Timo Jaeger, Mika Lindvall, Anders Karlén, Philippe Glaser, Jennifer Herrmann, Marco Pieroni, Bertrand Aigle, Evi Stegmann, Heather Graz, Andrea Schiefer, Jean-Luc Pernodet, Thomas Hesterkamp, Rui Moreira, Heike Brötz-Oesterhelt, Andrew W. Truman, Andreas Keller, Ludovic Halby, Alexander Titz, José R. Tormo, Michael Graz, Kira J. Weissman, Olga Genilloud, Marc Stadler, Claus-Michael Lehr, Paola B. Arimondo, Mark Brönstrup, Savithri Ramurthy, Eriko Takano, Frédéric Peyrane, Mathias Winterhalter, Marnix H. Medema, Maarten van Dongen, Anna K. H. Hirsch, Achim Hoerauf, Helge B. Bode, Laurent Fraisse, Laura J. V. Piddock, Martin Empting, Brigitta Loretz, Yanyan Li, Heinz E. Moser, Tilmann Weber, Marcus Miethke, Silke Alt, Stefano Sabatini, Wolfgang Wohlleben, Peter Hammann, Stefano Donadio, Andriy Luzhetskyy, Myriam Seemann, Rolf Müller, Hrvoje Petković
Publikováno v:
Nature Reviews. Chemistry
Nature Reviews Chemistry
Nature Reviews Chemistry, Nature Publishing Group, 2021, 5 (10), pp.726-749. ⟨10.1038/s41570-021-00313-1⟩
Nature Reviews Chemistry, 5, 726-749
Nature Reviews Chemistry, 2021, 5 (10), pp.726-749. ⟨10.1038/s41570-021-00313-1⟩
Nature Reviews Chemistry 5 (2021)
Nature Reviews Chemistry
Nature Reviews Chemistry, Nature Publishing Group, 2021, 5 (10), pp.726-749. ⟨10.1038/s41570-021-00313-1⟩
Nature Reviews Chemistry, 5, 726-749
Nature Reviews Chemistry, 2021, 5 (10), pp.726-749. ⟨10.1038/s41570-021-00313-1⟩
Nature Reviews Chemistry 5 (2021)
An ever-increasing demand for novel antimicrobials to treat life-threatening infections caused by the global spread of multidrug-resistant bacterial pathogens stands in stark contrast to the current level of investment in their development, particula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6afeefa93064508d90818e2ce9e55e
https://pubmed.ncbi.nlm.nih.gov/34426795
https://pubmed.ncbi.nlm.nih.gov/34426795
Autor:
Frédéric Peyrane, Pascale Clivio
Publikováno v:
Photochemical & Photobiological Sciences. 12:1366-1374
The DNA cis-syn cyclobutane photoproduct formed between two adjacent cytosine residues is highly mutagenic and responsible for the tandem CC to TT transition. However, its instability has prevented its in vitro study, so far. With a view to prepare o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4580a4667d8c5eaacd33463d156346f4
https://doi.org/10.1039/c3pp25402j
https://doi.org/10.1039/c3pp25402j
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2006, 71(4), pp.1742-1745. ⟨10.1021/jo0524066⟩
Journal of Organic Chemistry, American Chemical Society, 2006, 71(4), pp.1742-1745. ⟨10.1021/jo0524066⟩
Under aqueous conditions, 4-azidouracil/tetrazolo[1,5-c]pyrimidin-5(6H)-one nucleosides undergo a very efficient photochemical nitrogen elimination and ring expansion to 1,3,5-triazepin-2,4-dione nucleosides whose structure has been confirmed by X-ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b72d0efe0b868c4292b908de6b65a7
https://hal.archives-ouvertes.fr/hal-00020660
https://hal.archives-ouvertes.fr/hal-00020660
Autor:
Pascale Clivio, Frédéric Peyrane
Publikováno v:
Organicbiomolecular chemistry. 3(9)
4-Thio oxathiaphosphepane nucleosides 2–4 undergo a rearrangement in pyridine that leads selectively to the β anomer of the 2′-deoxy-5,6-dihydro-4-thiouridine derivative 5. This diastereoselective reaction proceeds through a multistep mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f782c3417dd9380eafd71b19a658afd
https://pubmed.ncbi.nlm.nih.gov/15858650
https://pubmed.ncbi.nlm.nih.gov/15858650
Publikováno v:
ChemInform. 34
Treatment of 2'-deoxy-3',5'-dithexyldimethylsilyl-5,6-dihydrouridine with Lawesson's reagent led to the expected C4-thiolated derivative together with a number of oxathiaphosphepane isomers which resulted from the heat reversible incorporation of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b765f8b8c3d93b7ef23ae6dd8e9c71f
https://doi.org/10.1002/chin.200327182
https://doi.org/10.1002/chin.200327182
Autor:
Pascale Clivio, Frédéric Peyrane
Publikováno v:
The Journal of Organic Chemistry. 70:1961-1962
Treatment of 4-azido-2-pyrimidinone nucleoside 1 with MeOH/K2CO3 or ammonium hydroxide led to derivatives 2 and 3, respectively. Both compounds derived from a nucleophilic addition at the modified base 2-position. These results contrast with the prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdca98d149d2c47ef98eca5be42fc97
https://doi.org/10.1021/jo0479765
https://doi.org/10.1021/jo0479765