Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Frédéric Perraud"'
Autor:
Serge Braun, Andrea Pavirani, Frédéric Perraud, Christine Thioudellet, Reiner Bischoff, Horst Homann, Majid Mehtali, Marie-Christine Claudepierre, Monika Lusky, Catherine Escriou
Publikováno v:
Cytotechnology. 30:181-189
We have developed and characterized cultures of healthy and dystrophic canine myoblasts for the evaluation of various gene transfer protocols. The number of desmin-positive myoblasts was elevated (>>80%) in cultures of myoblasts obtained from differe
Autor:
Wilfried Dalemans, Eve Devinoy, Dominique Thépot, Louis-Marie Houdebine, Andrea Pavirani, Frédéric Perraud, Rainer Bischoff, Dalila Ali-Hadji, Eric Degryse
Publikováno v:
FEBS Letters
FEBS Letters, Wiley, 1992, 305 (3), pp.265-268
FEBS Lett., 305(3), 265-268
FEBS Letters, Wiley, 1992, 305 (3), pp.265-268
FEBS Lett., 305(3), 265-268
We have investigated whether DNA regions present in the rabbit whey acidic protein (WAP) promoter/5′ flanking sequence could potentially confer. in vivo, high level expression or reporter genes. Transgenic mice were generated expressing a variant o
Publikováno v:
Cytotechnology. 9:69-75
We have used transgenic mouse technology to establish immortalized hepatoma cell lines stably secreting heterologous proteins, such as human alpha 1-antitrypsin and human factor IX. Hepatocyte-specific regulatory DNA sequences were used to target bot
Autor:
Cavallini B, Halluard C, Bruce Acres, Frédéric Perraud, N. Accart, C. Thioudellet, Patrick Rodriguez, Jean-Marc Balloul, Andrea Pavirani, S. Braun, Ali-Hadji D
Publikováno v:
Gene therapy. 7(17)
Intramuscular administration of plasmid expressing full-length human dystrophin in dystrophin-deficient adult mdx mice resulted in humoral and weak specific T cell responses against the human dystrophin protein. Following plasmid injection, human dys
Autor:
Christine Thioudellet, Françoise Längle-Rouault, Frédéric Perraud, Marie-Christine Claudepierre, Dalila Ali-Hadji, Klaus Schughart, Christine Jenny, Andrea Pavirani, Serge Braun
Publikováno v:
FEBS letters. 454(3)
As a pharmacological approach to potentially improve gene transfer efficiency into skeletal muscle cells, glucocorticoids were shown here to allow efficient transfection of cultured and mouse human myoblasts, human pulmonary A549 cells, but not dog m
Autor:
Rainer Bischoff, Andrea Pavirani, N. Silvestre, Frédéric Perraud, Otmane Boussif, Y. Cordier, Ulla B. Rasmussen, Klaus Schughart, D.A. Hadji, N. Accart, Hanno Kolbe
Publikováno v:
Human Gene Therapy, 10(18), 2891-2905. MARY ANN LIEBERT, INC
A novel type of synthetic vector, termed solvoplex, is described that can greatly enhance gene expression in lung after intrapulmonary delivery. Solvoplexes consist of plasmid DNA and organic solvents. Several organic solvents were analyzed, and luci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5082c6e4099c0bfafce00430f2c1ad29
https://research.rug.nl/en/publications/160b948a-0e58-4620-936c-a006b55000f3
https://research.rug.nl/en/publications/160b948a-0e58-4620-936c-a006b55000f3
Autor:
Andrea Pavirani, Frédéric Perraud, Hanno V. J. Kolbe, D.A. Hadji, N. Accart, Rainer Bischoff, Klaus Schughart, O. Boussif, N. van Rooijen, U.B. Rasmussen
Publikováno v:
Gene Ther., 6(3), 448-453. Nature Publishing Group
One of the main limitations for the use of synthetic vectors in gene therapy is their relatively low in vivo efficiency when compared with viral vectors. Here, we describe a pretreatment protocol with liposome-encapsulated clodronate in mice by which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb8f237e196bd37a743906294bd20af
https://research.rug.nl/en/publications/cf41f492-1707-4913-bfdc-994b651c734b
https://research.rug.nl/en/publications/cf41f492-1707-4913-bfdc-994b651c734b
Autor:
Yves Cordier, Frédéric Perraud, Christine Thioudellet, Andrea Pavirani, Serge Braun, Rainer Bischoff
Publikováno v:
Analytical Biochemistry, 254(1), 69-81. ACADEMIC PRESS INC ELSEVIER SCIENCE
Transfection of satellite cells from dog muscle (myoblasts) in primary culture has been optimized with respect to the position of the cholesteryl moiety along the polyamine chain of spermidine or spermine. Spermidine or spermine were derivatized with
Autor:
Frédéric Perraud, Laurence Michel-Calemard, Hélène Levrey, Claude Sene, Christophe Malcus, Jacques Bienvenu, Michèle Aymard, Andrea Pavirani, Satta So, Marie Pierre Layani, Christian Paulin, Véronique Jagneaux, Christian Schatz, Michael Courtney, Gerd Döring, Yves Morel, Danièle Thouvenot, Didier Lamy, Bernard Gilly, Laurence Rodillon, Nathalie Accart, Françoise Poitevin, Hélène Bernon, Robert Gilly, Gabriel Bellon, Françoise Touraine-Moulin
Publikováno v:
Human gene therapy. 8(1)
Ad CFTR, a replication-deficient adenovirus expressing the human cystic fibrosis transmembrane conductance regulator (CFTR), was administered by aerosolization in a single escalating dose to three pairs (cohorts) of cystic fibrosis (CF) patients. Buf
Autor:
Andrea Pavirani, Dominique Dreyer, Wilfried Dalemans, Frédéric Perraud, Thérèse Faure, Jean-Louis Gendrault, Dalila Ali-Hadji
Publikováno v:
Experimental cell research. 195(1)
Hepato-speciflc regulatory (promoter/enhancer) DNA sequences were used for targeting the expression of onc genes, such as murine c-myc and Simian Virus 40 T Antigen, to hepatocytes of transgenic mice which subsequently developed hepatocellular carcin