Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Frédéric P Lemaigre"'
Autor:
Paul Van Liedekerke, Lila Gannoun, Axelle Loriot, Tim Johann, Frédéric P Lemaigre, Dirk Drasdo
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2, p e1009653 (2022)
Biliary ducts collect bile from liver lobules, the smallest functional and anatomical units of liver, and carry it to the gallbladder. Disruptions in this process caused by defective embryonic development, or through ductal reaction in liver disease
Externí odkaz:
https://doaj.org/article/63d0be599a614ee3bfc0e8aeb4bbd09c
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 4, p e1008854 (2021)
Colony Stimulating Factor 1 Receptor (CSF1R) is a potential target for anti-epileptic drugs. However, inhibition of CSF1R is not well tolerated by patients, thereby prompting the need for alternative targets. To develop a framework for identification
Externí odkaz:
https://doaj.org/article/f0701f2d6cc841c086bc9d2ad2ad8268
Autor:
Sophie Pirenne, Fátima Manzano-Núñez, Axelle Loriot, Sabine Cordi, Lieven Desmet, Selda Aydin, Catherine Hubert, Sébastien Toffoli, Nisha Limaye, Christine Sempoux, Mina Komuta, Laurent Gatto, Frédéric P. Lemaigre
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Most studies on tumour progression from precursor lesion toward gallbladder adenocarcinoma investigate lesions sampled from distinct patients, providing an overarching view of pathogenic cascades. Whether this reflects the tumouri
Externí odkaz:
https://doaj.org/article/888ee42661c44f70b730f4a7d0dccaca
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157140 (2016)
The differentiation status of tumor cells, defined by histomorphological criteria, is a prognostic factor for survival of patients affected with intrahepatic cholangiocarcinoma (ICC). To strengthen the value of morphological differentiation criteria,
Externí odkaz:
https://doaj.org/article/34fd588680e4428999e498e1f0fdc5a3
Autor:
Jean-Bernard Beaudry, Sabine Cordi, Céline Demarez, Sébastien Lepreux, Christophe E Pierreux, Frédéric P Lemaigre
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0132295 (2015)
Biliary cysts in adult patients affected by polycystic liver disease are lined by cholangiocytes that proliferate, suggesting that initiation of cyst formation depends on proliferation. Here, we challenge this view by analyzing cyst-lining cell proli
Externí odkaz:
https://doaj.org/article/fe5de6316ad443bd9d3d3e83f198082f
Autor:
Frédéric P. Lemaigre
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 6, Pp 1064-1065 (2024)
Externí odkaz:
https://doaj.org/article/3e29846b9bd84e3891ec916eb5a91e0e
Autor:
Patrick Jacquemin, Frédéric P. Lemaigre, Mariano Barbacid, Luc Bouwens, Carmen Guerra, Jean S. Fain, Maxime Libert, Jonathan Baldan, Hajar Dahou, Nicolas Dauguet, Axelle Loriot, Younes Achouri, Mohamad Assi
Document describing important findings related to the main manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7365ea47b69027aa0851951d5bd97b51
https://doi.org/10.1158/0008-5472.22426914
https://doi.org/10.1158/0008-5472.22426914
Autor:
Patrick Jacquemin, Frédéric P. Lemaigre, Mariano Barbacid, Luc Bouwens, Carmen Guerra, Jean S. Fain, Maxime Libert, Jonathan Baldan, Hajar Dahou, Nicolas Dauguet, Axelle Loriot, Younes Achouri, Mohamad Assi
Document describing important mouse lines, treatment protocols, antibodies and primers used in the present study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa7f094f4b7e772e21332935d3ccddc
https://doi.org/10.1158/0008-5472.22426911.v1
https://doi.org/10.1158/0008-5472.22426911.v1
Autor:
Patrick Jacquemin, Frédéric P. Lemaigre, Mariano Barbacid, Luc Bouwens, Carmen Guerra, Jean S. Fain, Maxime Libert, Jonathan Baldan, Hajar Dahou, Nicolas Dauguet, Axelle Loriot, Younes Achouri, Mohamad Assi
Pancreatic acinar cells are a cell type of origin for pancreatic cancer that become progressively less sensitive to tumorigenesis induced by oncogenic Kras mutations after birth. This sensitivity is increased when Kras mutations are combined with pan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f600343301e489bb372050ce770fb44
https://doi.org/10.1158/0008-5472.c.6512493.v1
https://doi.org/10.1158/0008-5472.c.6512493.v1
Autor:
Frédéric P. Lemaigre
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol. 13, no.6, p. 1847-1848 (2022)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c870d7f483eb79a39dc93fb92a5b755
https://hdl.handle.net/2078.1/262566
https://hdl.handle.net/2078.1/262566