Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Frédéric Mievis"'
Autor:
Maria Elisa Serrano, Guillaume Becker, Mohamed Ali Bahri, Alain Seret, Nathalie Mestdagh, Joël Mercier, Frédéric Mievis, Fabrice Giacomelli, Christian Lemaire, Eric Salmon, André Luxen, Alain Plenevaux
Publikováno v:
Molecules, Vol 24, Iss 9, p 1705 (2019)
The synaptic vesicle protein 2 (SV2) is involved in synaptic vesicle trafficking. The SV2A isoform is the most studied and its implication in epilepsy therapy led to the development of the first SV2A PET radiotracer [18F]UCB-H. The objective of this
Externí odkaz:
https://doaj.org/article/84ac241c4d9c406ca812308191683699
Autor:
Guillaume Becker, Robrecht Raedt, Alain Seret, Fabrice Giacomelli, Alain Plenevaux, André Luxen, Eric Salmon, Christian Lemaire, Frédéric Mievis, Mohamed Ali Bahri, Bernard Rogister, Charlotte Germonpré, Maria Elisa Serrano
Publikováno v:
Molecular Imaging and Biology
MOLECULAR IMAGING AND BIOLOGY
MOLECULAR IMAGING AND BIOLOGY
Purpose The main purpose of this study was to understand how the positron emission tomography (PET) measure of the synaptic vesicle 2A (SV2A) protein varies in vivo during the development of temporal lobe epilepsy (TLE) in the kainic acid rat model.
Autor:
Bénédicte Guillaume, Frédéric Mievis, Fabrice Giacomelli, Mohamed Ali Bahri, Christian Degueldre, Christian Lemaire, Evelyne Balteau, Eric Salmon, Christine Bastin
Publikováno v:
Alzheimer disease and associated disorders. 35(4)
OBJECTIVES The current study addresses the nature of memory difficulties in amnestic mild cognitive impairment (aMCI). Whereas recollection is consistently found to be impaired in aMCI, the results on familiarity are divergent. One potential factor t
Autor:
Fabrice Giacomelli, Mohamed Ali Bahri, Alain Plenevaux, Guillaume Becker, Alain Seret, Frédéric Mievis, Christian Lemaire, Maria Elisa Serrano, André Luxen, Eric Salmon
Publikováno v:
Molecular Imaging and Biology. 21:888-897
[18F]UCB-H is a specific positron emission tomography (PET) biomarker for the Synaptic Vesicle protein 2A (SV2A), the binding site of the antiepileptic drug levetiracetam. With a view to optimising acquisition time and simplifying data analysis with
Autor:
Maria Elisa, Serrano, Mohamed Ali, Bahri, Guillaume, Becker, Alain, Seret, Frédéric, Mievis, Fabrice, Giacomelli, Christian, Lemaire, Eric, Salmon, André, Luxen, Alain, Plenevaux
Publikováno v:
Molecular imaging and biology. 21(5)
[Twelve Sprague Dawley male rats, pre-treated with three different doses of levetiracetam were employed to develop the methodology. Three additional kainic acid (KA) treated rats (temporal lobe epilepsy model) were also used to test the procedure. Im
Autor:
Irène Scagnol, Noëlla Bletard, Philippe Coucke, Philippe Delvenne, Frédéric Mievis, Philippe Martinive, Fabrice Giacomelli, Nadia Withofs, Roland Hustinx, Didier Cataldo, Sanjiv S. Gambhir, Jean Vanderick
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 43:654-662
Our primary objective was to determine if [(18)F]FPRGD2 PET/CT performed at baseline and/or after chemoradiotherapy (CRT) could predict tumour regression grade (TRG) in locally advanced rectal cancer (LARC). Secondary objectives were to compare basel
Autor:
Dominique de Seny, Sanjiv S. Gambhir, Edith Charlier, Nadia Withofs, Christine Mella, Fabrice Giacomelli, Frédéric Mievis, Paolo Simoni, Victoria Alvarez-Miezentseva, Roland Hustinx, Michel Malaise, Olivier Malaise
Publikováno v:
Annals of Nuclear Medicine. 29:839-847
This work reports on musculoskeletal uptake of 18F-FPRGD2, targeting the integrin αvβ3, in patients who had undergone 18F-FPRGD2 positron emission tomography combined with computed tomography (PET/CT) for oncologic purposes. Whole-body 18F-FPRGD2 P
Autor:
David Waltregny, Nadia Withofs, Roland Hustinx, Nicolas Signolle, Pierre Lovinfosse, Fabrice Giacomelli, Didier Cataldo, Sanjiv S. Gambhir, Eugène Mutijima Nzaramba, Joan Somja, Frédéric Mievis
Publikováno v:
Journal of Nuclear Medicine. 56:361-364
This study aimed to correlate (18)F-FB-mini-PEG-E[c(RGDyK)](2) ((18)F-FPRGD2) uptake to integrin αvβ3 expression and angiogenesis in renal tumors.(18)F-FPRGD2 PET/CT was performed on 27 patients before surgical resection (median 4 d) of a renal mas
Autor:
Alain Seret, Tim Buchanan, Christian Otoul, Frédéric Mievis, Florian Bretin, Fabrice Giacomelli, Nathalie Mestdagh, F Koestler, Geoffrey Warnock, André Luxen, Joël Aerts, Eric Salmon, Alain Plenevaux, Claire Bernard, Roland Hustinx, Mohamed Ali Bahri, Christian Degueldre
Publikováno v:
Molecular Imaging and Biology. 17:557-564
[(18)F]UCB-H is a novel radiotracer with a high affinity for synaptic vesicle glycoprotein 2A (SV2A), a protein expressed in synaptic vesicles. SV2A is the binding site of levetiracetam, a "first-in-class" antiepileptic drug with a distinct but still
Autor:
Frédéric Mievis, Bénédicte Guillaume, Fabienne Collette, Sarah Genon, Christian Lemaire, Christine Bastin, Eric Salmon, Jessica Simon, Mohamed Ali Bahri, Rachel A. Diana, Andrew P. Yonelinas
Publikováno v:
Neuropsychologia, vol 63, iss 1
This study investigated the impact of Alzheimer׳s disease (AD) on conjunctive and relational binding in episodic memory. Mild AD patients and controls had to remember item–color associations by imagining color either as a contextual association (r