Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Frédéric J. J. Chain"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Modifications to highly conserved developmental gene regulatory networks are thought to underlie morphological diversification in evolution and contribute to human congenital malformations. Relationships between gene expression and morpholog
Externí odkaz:
https://doaj.org/article/0154bdbf2a834df3ac7f2f5a4d822819
Autor:
Frédéric J. J. Chain, Britta S. Meyer, Melanie J. Heckwolf, Sören Franzenburg, Christophe Eizaguirre, Thorsten B. H. Reusch
Publikováno v:
Evolutionary Applications, Vol 17, Iss 7, Pp n/a-n/a (2024)
Abstract Duplicated genes provide the opportunity for evolutionary novelty and adaptive divergence. In many cases, having more gene copies increases gene expression, which might facilitate adaptation to stressful or novel environments. Conversely, ov
Externí odkaz:
https://doaj.org/article/86cd5e1cd9d640cd98e91a1237d51d38
Autor:
Daniel P. Dacey, Frédéric J. J. Chain
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-25 (2021)
Abstract Background Taxonomic classification of genetic markers for microbiome analysis is affected by the numerous choices made from sample preparation to bioinformatics analysis. Paired-end read merging is routinely used to capture the entire ampli
Externí odkaz:
https://doaj.org/article/5b33838102ab49208383deb255b6765f
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Despite being one of the primary mechanisms of gene expression regulation in eukaryotes, alternative splicing is often overlooked in ecotoxicogenomic studies. The process of alternative splicing facilitates the production of multi
Externí odkaz:
https://doaj.org/article/c32875525174479890268ad5c6cffaba
Autor:
Daniel P. Dacey, Frédéric J. J. Chain
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Mosquitoes are one of the deadliest animals on earth because of their ability to transmit a wide range of human pathogens. Traditional mosquito control methods use chemical insecticides, but with dwindling long-term effectiveness and negative effects
Externí odkaz:
https://doaj.org/article/d6c016f659134e2785a49fc79f1ba61d
Autor:
Shelbi E. Gill, Frédéric J. J. Chain
Publikováno v:
Journal of Molecular Evolution. 91:24-32
The study of spontaneous mutation rates has revealed a wide range of heritable point mutation rates across species, but there are comparatively few estimates for large-scale deletion and duplication rates. The handful of studies that have directly ca
To safeguard biodiversity in a changing climate, we require taxonomic information about species turnover and insights into the health of organisms. Environmental DNA approaches are increasingly used for species identification, but cannot provide func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::061c758cacd86fbfa03506e874093892
https://doi.org/10.1101/2022.10.06.510878
https://doi.org/10.1101/2022.10.06.510878
Autor:
Frédéric J J Chain, Katherine M. Huang
Publikováno v:
Evolution. 75:706-718
Gene duplication is an important driver of genomic diversity that can promote adaptive evolution. However, like most mutations, a newly duplicated gene is often deleterious and removed from the genome by drift or natural selection. The early molecula
Publikováno v:
Heredity
Eukaryotic genomes frequently acquire new protein-coding genes which may significantly impact an organism’s fitness. Novel genes can be created, for example, by duplication of large genomic regions or de novo, from previously non-coding DNA. Either
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-14 (2020)
BMC Genomics
BMC Genomics
Background Despite being one of the primary mechanisms of gene expression regulation in eukaryotes, alternative splicing is often overlooked in ecotoxicogenomic studies. The process of alternative splicing facilitates the production of multiple mRNA