Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Frédéric Heitz"'
Autor:
Roger S. Goody, Gilles Divita, Véronique Robert-Hebmann, Christian Devaux, Jean Mery, May C. Morris, Laurent Chaloin, Frédéric Heitz
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2019, 294 (16), pp.6658. ⟨10.1074/jbc.AAC119.008640⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2019, 294 (16), pp.6658. ⟨10.1074/jbc.AAC119.008640⟩
The biologically relevant and active forms of human immunodeficiency viruses type 1 and 2 reverse transcriptase found in infectious virions are heterodimers produced in a two-step dimerization process. Dimerization involves first the rapid associatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65b2506ebe74e4947d77c389f7d621f
https://europepmc.org/articles/PMC6484107/
https://europepmc.org/articles/PMC6484107/
Publikováno v:
International Journal of Peptide and Protein Research. 33:379-385
A 31-residue peptide, retro gramicidin A-dAla-gramicidin A, mimicking a gramicidin A dimer was prepared by solid phase method using a 4-(oxymethyl)-Pam resin and BOC as α amino protecting group. To avoid any possible formation of gramicidin A, coupl
Publikováno v:
International Journal of Peptide and Protein Research. 47:62-69
Gelsolin and thymosin β4 appear to be two important actin-associated proteins involved in the regulation of actin polymerization. It has been widely demonstrated that thymosin is the major cellular actin-sequestering factor shifting the polymerizati
Publikováno v:
International Journal of Peptide and Protein Research. 34:387-393
The conformations of a cyclic octapeptide built with an alternation of D and L residues are investigated on the basis of 1H n.m.r. and CD data. The cyclooctapeptide can form structures which are specific to the alternating D-L sequence. This peptide
Autor:
Frédéric Heitz, Myriam Chentouf, Cédric Bès, Andreas Plückthun, Hélène Breton, Anne Dominique Lajoix, René Gross, Samuel Troadec, Thierry Chardès
Publikováno v:
Biochemical and Biophysical Research Communications. 343:334-344
By inserting the CB1 paratope-derived peptide (PDP) from the anti-CD4 13B8.2 antibody binding pocket into each of the three exposed loops of the protein inhibitor of neuronal nitric oxide synthase (PIN), we have combined the anti-CD4 specificity of t
Autor:
May C. Morris, Edwige Gros, Julien Depollier, Sébastien Deshayes, Gilles Divita, Frédéric Heitz, Gudrun Aldrian-Herrada
Publikováno v:
Biochimica et Biophysica Acta:Biomembranes
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2006, 1758 (3), pp.384-393. ⟨10.1016/j.bbamem.2006.02.006⟩
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2006, 1758 (3), pp.384-393. ⟨10.1016/j.bbamem.2006.02.006⟩
International audience; The development of therapeutic peptides and proteins is limited by the poor permeability and the selectivity of the cell membrane. The discovery of protein transduction domains has given a new hope for administration of large
Publikováno v:
ChemBioChem. 6:1254-1262
The ability of cationic phosphoramidate pyrimidine alpha-oligonucleotides (ONs) to form triplexes with DNA duplexes was investigated by UV melting experiments, circular dichroism spectroscopy and gel mobility shift experiments. Replacement of the pho
Autor:
Sébastien Deshayes, Richard B. Cole, Frédéric Heitz, Pierre-Emmanuel Milhiet, Christian Le Grimellec, Thomas Plénat, Sylvie Boichot
Publikováno v:
Langmuir. 20:9255-9261
The mesoscopic organization adopted by two primary amphipathic peptides, P(beta) and P(alpha), in Langmuir-Blodgett (LB) films made of either the pure peptide or peptide-phospholipid mixtures was examined by atomic force microscopy. P(beta), a potent
Autor:
Frédéric Heitz, Sylvie Boichot, Ulrike Krauss, Kerstin Wagner, Annette G. Beck-Sickinger, Christian Le Grimellec, Andrey V. Kajava, Nicole Van Mau
Publikováno v:
Biophysical Journal. 87:386-395
Human calcitonin and its C-terminal fragment 9–32 (hCT(9–32)) administered in a spray translocate into respiratory nasal epithelium with an effect similar to intravenous injection. hCT(9–32) is an efficient carrier to transfer the green fluores
Autor:
Gilles Divita, Sébastien Deshayes, Frédéric Heitz, Christian Le Grimellec, Thomas Plénat, Gudrun Aldrian-Herrada
Publikováno v:
Biochemistry. 43:7698-7706
To identify rules for the design of efficient cell-penetrating peptides that deliver therapeutic agents into subcellular compartments, we compared the properties of two closely related primary amphipathic peptides that mainly differ by their conforma