Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Frédéric Hague"'
Autor:
Stefan Djordjevic, Raphaël Itzykson, Frédéric Hague, Delphine Lebon, Julien Legrand, Hakim Ouled‐Haddou, Guillaume Jedraszak, Juliette Harbonnier, Louison Collet, Etienne Paubelle, Jean‐Pierre Marolleau, Loïc Garçon, Thomas Boyer
Publikováno v:
Molecular Oncology, Vol 18, Iss 6, Pp 1571-1592 (2024)
Calcium is a ubiquitous messenger that regulates a wide range of cellular functions, but its involvement in the pathophysiology of acute myeloid leukemia (AML) is not widely investigated. Here, we identified, from an analysis of The Cancer Genome Atl
Externí odkaz:
https://doaj.org/article/f6cb7082898f4542b2cf244700888f91
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10687 (2022)
In the fight against cancer, therapeutic strategies using cisplatin are severely limited by the appearance of a resistant phenotype. While cisplatin is usually efficient at the beginning of the treatment, several patients endure resistance to this ag
Externí odkaz:
https://doaj.org/article/f2ad9d49e33e4bb183cbac6d7fb27d04
Autor:
Julie Schnipper, Sana Kouba, Frédéric Hague, Alban Girault, Pierre Rybarczyk, Marie-Sophie Telliez, Stéphanie Guénin, Riad Tebbakha, Henri Sevestre, Ahmed Ahidouch, Stine Falsig Pedersen, Halima Ouadid-Ahidouch
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7923 (2022)
Dysregulation of the transient receptor canonical ion channel (TRPC1) has been found in several cancer types, yet the underlying molecular mechanisms through which TRPC1 impacts pancreatic ductal adenocarcinoma (PDAC) cell proliferation are incomplet
Externí odkaz:
https://doaj.org/article/51597b621c1c4cb897885542fed1f27c
Autor:
Julie, Schnipper, Sana, Kouba, Frédéric, Hague, Alban, Girault, Marie-Sophie, Telliez, Stéphanie, Guénin, Ahmed, Ahidouch, Stine Falsig, Pedersen, Halima, Ouadid-Ahidouch
Publikováno v:
Cancers. 14(19)
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with a low overall survival rate of less than 10% and limited therapeutic options. Fluctuations in tumor microenvironment pH are a hallmark of PDAC development and p
Publikováno v:
International journal of molecular sciences. 23(18)
In the fight against cancer, therapeutic strategies using cisplatin are severely limited by the appearance of a resistant phenotype. While cisplatin is usually efficient at the beginning of the treatment, several patients endure resistance to this ag
Autor:
Loïc Louvet, Gaëlle Lenglet, A. Michaela Krautzberger, Romuald Mentaverri, Frédéric Hague, Clara Kowalewski, Nassim Mahtal, Julie Lesieur, Anne‐Laure Bonnet, Caroline Andrique, Céline Gaucher, Cathy Gomila, Heinrich Schrewe, Pierre‐Louis Tharaux, Said Kamel, Catherine Chaussain, Isabelle Six
Publikováno v:
Journal of Cellular Physiology
Journal of Cellular Physiology, 2022, ⟨10.1002/jcp.30838⟩
Journal of Cellular Physiology, 2022, ⟨10.1002/jcp.30838⟩
International audience; Within the cardiovascular system, the protein vasorin (Vasn) is predominantly expressed by vascular smooth muscle cells (VSMCs) in the coronary arteries and the aorta. Vasn knockout (Vasn(-/-) ) mice die within 3 weeks of birt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127ad9bb4d4cd3e79beff4793a7792cb
https://u-picardie.hal.science/hal-03740510
https://u-picardie.hal.science/hal-03740510
Autor:
Nazim Benzerdjeb, Halima Ouadid-Ahidouch, Hakim Ouled-Haddou, Henri Sevestre, Loïc Garçon, Sana Kouba, Hiba Abou Daya, Frédéric Hague, Marie-Sophie Telliez, Charles Dayen
Publikováno v:
Cancers, Vol 13, Iss 2314, p 2314 (2021)
Cancers
Volume 13
Issue 10
Cancers
Volume 13
Issue 10
Simple Summary Lung cancer is recognized for having a very poor prognosis with an overall survival rate of 5-years not exceeding 15%. Platinum-doublet therapy is the most current chemotherapeutic treatment used to treat lung tumors. However, resistan
Autor:
Pierre Rybarczyk, Halima Ouadid-Ahidouch, Frédéric Hague, Alison Vanlaeys, Philippe Kischel, Bertrand Brassart, Sylvie Pasco-Brassart, Isabelle Dhennin-Duthille, Grégory Fouquet, Mathieu Gautier, Thibaut Lefebvre
Publikováno v:
Archives of Toxicology
Archives of Toxicology, Springer Verlag, 2020, 94 (3), pp.735-747. ⟨10.1007/s00204-020-02674-w⟩
Archives of Toxicology, 2020, 94 (3), pp.735-747. ⟨10.1007/s00204-020-02674-w⟩
Archives of Toxicology, Springer Verlag, 2020, 94 (3), pp.735-747. ⟨10.1007/s00204-020-02674-W⟩
Archives of Toxicology, Springer Verlag, 2020, 94 (3), pp.735-747. ⟨10.1007/s00204-020-02674-w⟩
Archives of Toxicology, 2020, 94 (3), pp.735-747. ⟨10.1007/s00204-020-02674-w⟩
Archives of Toxicology, Springer Verlag, 2020, 94 (3), pp.735-747. ⟨10.1007/s00204-020-02674-W⟩
Cadmium is a xenobiotic involved in neoplastic transformation. Cadmium enters the cells through divalent cation transporters including the Transient Receptor Potential Melastatin-related 7 (TRPM7) which is known to be involved in cancer cell fate. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60872e02da46f636d025a212d79be639
https://hal.univ-reims.fr/hal-02933064/document
https://hal.univ-reims.fr/hal-02933064/document
Autor:
Frédéric Hague, Catherine Leroy, Philippe Kischel, Lise Rodat-Despoix, Dirk Geerts, David Tulasne, Halima Ouadid-Ahidouch, Jessy Hasna
Publikováno v:
Hasna, J, Hague, F, Rodat-Despoix, L, Geerts, D, Leroy, C, Tulasne, D, Ouadid-Ahidouch, H & Kischel, P 2018, ' Orai3 calcium channel and resistance to chemotherapy in breast cancer cells : the p53 connection ', Cell Death and Differentiation, vol. 25, no. 4, pp. 693-707 . https://doi.org/10.1038/s41418-017-0007-1
Cell death and differentiation, 25, 691-705. Nature Publishing Group
Cell Death and Differentiation, 25(4), 693-707. Nature Publishing Group
Cell death and differentiation, 25, 691-705. Nature Publishing Group
Cell Death and Differentiation, 25(4), 693-707. Nature Publishing Group
Orai proteins are highly selective calcium channels playing an important role in calcium entry. Orai3 channels are overexpressed in breast cancer (BC) tissues, and involved in their proliferation, cell cycle progression and survival. Herein, we sough
Autor:
Frédéric Hague, Abdallah Mound, Béatrice Botia, Jan B. Parys, Alexia Vautrin-Glabik, Halima Ouadid-Ahidouch, Lise Rodat-Despoix, Arthur Foulon
Publikováno v:
Oncotarget
Breast cancer remains a research priority due to its invasive phenotype. Although the role of ion channels in cancer is now well established, the role of inositol (1,4,5)-trisphosphate (IP3) receptors (IP3Rs) remains enigmatic. If the three IP3Rs sub