Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Frédéric Gaspar"'
Autor:
Jean Terrier, Frédéric Gaspar, Pauline Gosselin, Olivier Raboud, Camille Lenoir, Victoria Rollason, Chantal Csajka, Caroline Samer, Pierre Fontana, Youssef Daali, Jean‐Luc Reny, for the OptimAT study group
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 12, Pp 1872-1883 (2023)
Abstract When used in real‐world conditions, substantial interindividual variations in direct oral anticoagulant (DOAC) plasma concentrations are observed for a given dose, leading to a risk of over‐ or under‐exposure and clinically significant
Externí odkaz:
https://doaj.org/article/1a99f15a9a8e4eef9631ce2e055ca3a6
Autor:
Frédéric Gaspar, Jean Terrier, Samantha Favre, Pauline Gosselin, Pierre Fontana, Youssef Daali, Camille Lenoir, Caroline Flora Samer, Victoria Rollason, Jean‐Luc Reny, Chantal Csajka, Monia Guidi
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 10, Pp 1541-1552 (2023)
Abstract This study aimed to characterize apixaban pharmacokinetics (PKs) and its variability in a real‐world clinical setting of hospitalized patients using a population PK (PopPK) approach. Model‐based simulations helped to identify factors tha
Externí odkaz:
https://doaj.org/article/12bfdd438de34a6eaf7cee9749ed2cb1
Autor:
Jean Terrier, Frédéric Gaspar, Monia Guidi, Pierre Fontana, Youssef Daali, Chantal Csajka, Jean‐Luc Reny
Publikováno v:
Clinical Pharmacology & Therapeutics. 112:353-363
Available data have shown an association between direct oral anticoagulant (DOAC) plasma concentration and clinical, particularly bleeding, events. Factors that may influence DOAC plasma concentration are therefore the focus of particular attention.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a286ffbbc74c66c6df9524ff21b72354
https://doi.org/10.1002/cpt.2649
https://doi.org/10.1002/cpt.2649
Autor:
Jean-Luc Reny, Frédéric Gaspar, Caroline Flora Samer, Pierre Fontana, Chantal Csajka, Daali Youssef, Jean Terrier
Publikováno v:
The American Journal of Medicine. 134:939-942
Even though direct oral anticoagulants (DOAC) are at risk for drug-drug interactions, they are barely mentioned in the dose adjustment guidelines and contradictory information is found in the summary of product characteristics of individual DOACs. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66225ab27a6b94bd90df01d14b9f68ba
https://doi.org/10.1016/j.amjmed.2021.04.003
https://doi.org/10.1016/j.amjmed.2021.04.003
Autor:
Claire Coumau, Frederic Gaspar, Jean Terrier, Angela Schulthess-Lisibach, Monika Lutters, Marie-Annick Le Pogam, Chantal Csajka
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Toxicity or treatment failure related to drug-drug interactions (DDIs) are known to significantly affect morbidity and hospitalization rates. Despite the availability of numerous databases for DDIs identification and management, their inf
Externí odkaz:
https://doaj.org/article/1c60891baf2e4fc6b4d1b63ac225f268
Autor:
Catalina, Barceló, Frédéric, Gaspar, Manel, Aouri, Alice, Panchaud, Margalida, Rotger, Monia, Guidi, Matthias, Cavassini, Thierry, Buclin, Laurent A, Decosterd, Chantal, Csajka, S, Yerly
Publikováno v:
The Journal of antimicrobial chemotherapy. 71(7)
OBJECTIVES Co-formulated elvitegravir, cobicistat, tenofovir disoproxil fumarate and emtricitabine is among the preferred regimens for first-line ART. A population approach was used to characterize the pharmacokinetics of elvitegravir and cobicistat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b152f6a5dbb647cc8dd84c055c43d635
https://pubmed.ncbi.nlm.nih.gov/27029846
https://pubmed.ncbi.nlm.nih.gov/27029846
Autor:
Frederic Gaspar, Monika Lutters, Patrick Emanuel Beeler, Pierre Olivier Lang, Bernard Burnand, Fabio Rinaldi, Christian Lovis, Chantal Csajka, Marie-Annick Le Pogam
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 11, p e40456 (2022)
BackgroundOne-third of older inpatients experience adverse drug events (ADEs), which increase their mortality, morbidity, and health care use and costs. In particular, antithrombotic drugs are among the most at-risk medications for this population. R
Externí odkaz:
https://doaj.org/article/2092b630904a42268d50fec77e89ec24
Autor:
Mélanie Ahoba, Frédéric Gaspart
Publikováno v:
Agricultural and Food Economics, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract This article analyzes the link between world prices and producer prices of rubber in Côte d’Ivoire. Using monthly data from 2006 to 2016, we gave special attention to structural breaks in the data and asymmetry in the transmission process
Externí odkaz:
https://doaj.org/article/e6cbeed0fbb14d18a8b410099daac355
Publikováno v:
Forests, Vol 12, Iss 4, p 431 (2021)
Forest dynamics are changing at a local and global level, with multiple social and environmental implications. The current literature points to different theories and hypotheses to explain these forest dynamics. In this paper, we formalized some of t
Externí odkaz:
https://doaj.org/article/45200f302f8f46d0b3352eb5770665e4
Publikováno v:
Environmental Research Letters, Vol 15, Iss 8, p 085007 (2020)
In the context of growing societal demands for land-based products, crop production can be increased through expanding cropland or intensifying production on cultivated land. Intensification can allow sparing land for nature, but it can also drive fu
Externí odkaz:
https://doaj.org/article/26c6c0b1e6b94dc2bc181d8af9790da0