Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Frédéric Gambino"'
Autor:
Elisabete Augusto, Frédéric Gambino
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Intelligence is the ability to learn appropriate responses to stimuli and the capacity to master new skills. Synaptic integration at the dendritic level is thought to be essential for this ability through linear and non-linear processing, by allowing
Externí odkaz:
https://doaj.org/article/1c76c66337a24c8f8b53eb5561ca8b63
Autor:
Rajesh Jayachandran, Xiaolong Liu, Somdeb Bosedasgupta, Philipp Müller, Chun-Lei Zhang, Despina Moshous, Vera Studer, Jacques Schneider, Christel Genoud, Catherine Fossoud, Frédéric Gambino, Malik Khelfaoui, Christian Müller, Deborah Bartholdi, Helene Rossez, Michael Stiess, Xander Houbaert, Rolf Jaussi, Daniel Frey, Richard A Kammerer, Xavier Deupi, Jean-Pierre de Villartay, Andreas Lüthi, Yann Humeau, Jean Pieters
Publikováno v:
PLoS Biology, Vol 12, Iss 3, p e1001820 (2014)
Cognitive and behavioral disorders are thought to be a result of neuronal dysfunction, but the underlying molecular defects remain largely unknown. An important signaling pathway involved in the regulation of neuronal function is the cyclic AMP/Prote
Externí odkaz:
https://doaj.org/article/5f217f7498134941886d3e2799f2c271
Autor:
Etienne Lonchamp, Frédéric Gambino, Jean Luc Dupont, Frédéric Doussau, Antoine Valera, Bernard Poulain, Jean-Louis Bossu
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30180 (2012)
N-methyl-D-aspartate (NMDA) receptors are associated with many forms of synaptic plasticity. Their expression level and subunit composition undergo developmental changes in several brain regions. In the mouse cerebellum, beside a developmental switch
Externí odkaz:
https://doaj.org/article/24eba025e7c44e47ae75d6d65b50445e
Autor:
Veronica Bianchi, Frédéric Gambino, Luca Muzio, Daniela Toniolo, Yann Humeau, Patrizia D'Adamo
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29763 (2012)
The GDI1 gene encodes αGDI, which retrieves inactive GDP-bound RAB from membranes to form a cytosolic pool awaiting vesicular release. Mutations in GDI1 are responsible for X-linked Intellectual Disability. Characterization of the Gdi1-null mice has
Externí odkaz:
https://doaj.org/article/6853150c802f488abaf4638ca73ba208
Autor:
Frédéric Gambino, Malik Khelfaoui, Bernard Poulain, Thierry Bienvenu, Jamel Chelly, Yann Humeau
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11399 (2010)
Rett syndrome (RTT) is a neuro-developmental disorder caused by loss of function of Mecp2--methyl-CpG-binding protein 2--an epigenetic factor controlling DNA transcription. In mice, removal of Mecp2 in the forebrain recapitulates most of behavioral d
Externí odkaz:
https://doaj.org/article/495d893b635c46309e444019b6683202
Autor:
Marjorie Varilh, Frédéric Gambino, Bénédicte Salin, Andrea Ruiz, Francisca Julio-Kalajzić, Giovanni Marsicano, Ana Covelo, Severine Deforges, Astrid Cannich, Vladimir Kouskoff, Carol Stella, Roman Serrat, Anna Beyeler, Sandrine Pouvreau, Federico Massa, Arnau Busquets-Garcia, Corinne Blancard, Nicolas Chenouard, Diego Destefani, Sebastien Delcasso, Laurie Robin
SummaryIntracellular calcium signaling underlies the astroglial control of synaptic transmission and plasticity. Mitochondria-endoplasmic reticulum contacts (MERCs) are key determinants of calcium dynamics, but their functional impact on astroglial r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b370bc81d46ff0d1f4f63b00787aa80d
https://hal.archives-ouvertes.fr/hal-03429979
https://hal.archives-ouvertes.fr/hal-03429979
Autor:
Anna Beyeler, Andrea Ruiz-Calvo, Ana Covelo, Arnau Busquets-Garcia, Severine Deforges, Vladimir Kouskoff, Astrid Cannich, Nicolas Chenouard, Corinne Blancard, Diego De Stefani, Marjorie Varilh, Giovanni Marsicano, Laurie M. Robin, Bénédicte Salin, Sandrine Pouvreau, Francisca Julio-Kalajzić, Frédéric Gambino, Federico Massa, Carol Stella, Roman Serrat, Sebastien Delcasso
Publikováno v:
Research Square
Intracellular calcium signaling underlies the astroglial control of brain functions. However, the cellular mechanisms regulating calcium handling by astrocytes are far from being understood. Mitochondria-endoplasmic reticulum contacts (MERCs) are key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12069c878211fc23aa15aede38249a3b
https://doi.org/10.21203/rs.3.rs-567001/v1
https://doi.org/10.21203/rs.3.rs-567001/v1
Autor:
Vladimir Kouskoff, Stéphane Pagès, Frédéric Gambino, Nicolas Chenouard, Anthony Holtmaat, Ronan Chéreau
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, ⟨10.1073/pnas.2024920118⟩
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (9), pp.e2024920118. ⟨10.1073/pnas.2024920118⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, ⟨10.1073/pnas.2024920118⟩
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (9), pp.e2024920118. ⟨10.1073/pnas.2024920118⟩
Significance Here we describe a mechanism for cortical map plasticity. Classically, representational map changes are thought to be driven by changes within cortico-cortical circuits, e.g., Hebbian plasticity of synaptic circuits that lost vs. maintai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81d7e29466a9fbb5bd53c1931074149
https://hal.archives-ouvertes.fr/hal-03429986
https://hal.archives-ouvertes.fr/hal-03429986
Autor:
Mattia Aime, Yann Humeau, Vladimir Kouskoff, Tiago Campelo, Nicolas Chenouard, Elisabete Augusto, Frédéric Gambino, Christelle Martin
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2020, 9, ⟨10.7554/elife.62594⟩
eLife, Vol 9 (2020)
eLife, eLife Sciences Publication, 2020, 9, ⟨10.7554/elife.62594⟩
eLife, Vol 9 (2020)
International audience; Survival depends on the ability of animals to select the appropriate behavior in response to threat and safety sensory cues. However, the synaptic and circuit mechanisms by which the brain learns to encode accurate predictors
Autor:
Nicolas Chenouard, Elisabete Augusto, Mattia Aime, Vladimir Kouskoff, Christelle Martin, Frédéric Gambino, Yann Humeau
Publikováno v:
bioRxiv
Survival depends on the ability of animals to select the appropriate behavior in response to threat and safety sensory cues. However, the synaptic and circuit mechanisms by which the brain learns to encode accurate predictors of threat and safety rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff4483366f767e6016c7eae3c6dc270
https://hal.archives-ouvertes.fr/hal-03006642
https://hal.archives-ouvertes.fr/hal-03006642